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  1. 6081
    “…Background: The mTOR pathway is altered in a multitude of cancers, including lung cancer; however, abnormal activation in this pathway is less common in lung adenocarcinoma (LUAD) than in lung squamous cell carcinoma (LUSC). …”
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    Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation
  2. 6082
    “…Glioblastoma is a highly lethal type of primary brain tumor that exhibits unrestricted growth and aggressive invasion capabilities, leading to a dismal prognosis despite a multitude of therapies. Multiple alterations in the expression level of genes and/or proteins have been identified in glioblastomas, including the activation of oncogenes and/or silencing of tumor-suppressor genes. …”
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    The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma
  3. 6083
    “…BACKGROUND: A multitude of epidemiological studies have shown that ambient fine particulate matter 2.5 (diameter < 2.5um; PM(2.5)) was associated with increased morbidity and mortality of chronic obstructive pulmonary disease (COPD). …”
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    Role of PM(2.5) in the development and progression of COPD and its mechanisms
  4. 6084
    “…Endothelial cells (ECs) are required for a multitude of cardiovascular clinical applications, such as revascularization of ischemic tissues or endothelialization of tissue engineered grafts. …”
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    Environmental Specification of Pluripotent Stem Cell Derived Endothelial Cells Toward Arterial and Venous Subtypes
  5. 6085
    “…In the present report, we review evidence indicating that the rodent CLA also has connections with structures identified in the rodent homolog of the salience network (SN), a circuit that directs attention towards the most relevant stimuli among a multitude of sensory inputs (Seeley et al., 2007; Menon and Uddin, 2010). …”
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    A Role for the Claustrum in Salience Processing?
  6. 6086
    “…The bacterial pathogen Pseudomonas aeruginosa uses three type VI secretion systems (T6SSs) to drive a multitude of effector proteins into eukaryotic or prokaryotic target cells. …”
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    Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner
  7. 6087
    “…Some software packages contain a multitude of features which are superfluous for most users. …”
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    Software solutions for evaluation and visualization of laser ablation inductively coupled plasma mass spectrometry imaging (LA-ICP-MSI) data: a short overview
  8. 6088
    “…This applies also to schizophrenia, for which genome-wide association studies have identified a large number of genetic risk loci, spanning hundreds of genes with diverse functionalities. Importantly, the multitude of the associated variants and their prevalence in the healthy population limit the potential of a reductionist functional genetics approach as a stand-alone solution to discover the disease pathology. …”
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    Biophysical Psychiatry—How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
  9. 6089
    por Xv, Fang-Yi, Sun, Alex, Gan, Yi, Hu, Hong-Jie
    Publicado 2019
    “…CONCLUSION: GDCs are quite rare in adults, with a multitude of symptoms, which is quite challenging for precise diagnosis before histological examination. …”
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    Gastric duplication cyst mimicking large cystic lymphangioma in an adult: A rare case report and review of the literature
  10. 6090
    por Helbich, Marco
    Publicado 2019
    “…People are exposed to the environments in which they currently live, and to a multitude of environments along their daily movements and through their residential relocations. …”
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    Dynamic Urban Environmental Exposures on Depression and Suicide (NEEDS) in the Netherlands: a protocol for a cross-sectional smartphone tracking study and a longitudinal population register study
  11. 6091
    “…Uropathogenic Escherichia coli (UPEC) express a multitude of virulence factors, which enable the bacteria to establish UTI. …”
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    Virulence factors of uropathogenic Escherichia coli (UPEC) and correlation with antimicrobial resistance
  12. 6092
    “…Biotherapeutics may contain a multitude of different post-translational modifications (PTMs) that need to be assessed and possibly monitored and controlled to ensure reproducible product quality. …”
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    Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics
  13. 6093
    “…The brain atlas is a fundamental resource for neuroimaging research, and have been created for a multitude animal models, however, none currently exist for the equine brain. …”
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    Equine Stereotaxtic Population Average Brain Atlas With Neuroanatomic Correlation
  14. 6094
    “…However, animals living in urban habitats are exposed to a multitude of anthropogenic disturbances, and it is likely that even species that appear to be thriving in noisy environments may suffer cumulative effects of these multiple disturbances that may together impact their fitness in urban environments.…”
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    Traffic noise exposure depresses plasma corticosterone and delays offspring growth in breeding zebra finches
  15. 6095
    “…However, the specific role of physician adoption of brand name drugs on the variation in patient-level prescription drug spending is still being investigated across a multitude of drug classes. Our study aims to add to the literature by determining the association between physician adoption of a first-in-class anti-diabetic (AD) drug, sitagliptin, and AD drug spending in the Medicare and Medicaid populations in Pennsylvania. …”
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    Association between physician adoption of a new oral anti-diabetic medication and Medicare and Medicaid drug spending
  16. 6096
    “…RESULTS: Students owned a multitude of devices however their preferences were for the 11 in. …”
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    The ‘connectaholic’ behind the curtain: medical student use of computer devices in the clinical setting and the influence of patients
  17. 6097
    “…KEY MESSAGE: Doubled-haploid libraries from landraces capture native genetic diversity for a multitude of quantitative traits and make it accessible for breeding and genome-based studies. …”
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    European maize landraces made accessible for plant breeding and genome-based studies
  18. 6098
    “…Function and dysfunction of endothelial cells are regulated by a multitude of factors. Endothelial cell research often requires in vitro cell culture experiments. …”
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    Outgrowth, proliferation, viability, angiogenesis and phenotype of primary human endothelial cells in different purchasable endothelial culture media: feed wisely
  19. 6099
    “…The regression model accounted for only 19% of the variability in the outcome of delay time, indicating a multitude of additional unidentified factors contributing to operating room efficiency.…”
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    Operating room first case start times: a metric to assess systems-based practice milestones?
  20. 6100
    “…Chronic inflammation and oxidative stress lead to a multitude of adverse cellular responses in target organs of chronic diabetic complications. …”
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    Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes
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