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  1. 6181
    “…Ca(2+)-activated Cl(−) channels (CaCCs) perform a multitude of functions including the control of cell excitability, regulation of cell volume and ionic homeostasis, exocrine and endocrine secretion, fertilization, amplification of olfactory sensory function, and control of smooth muscle cell contractility. …”
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    Molecular mechanisms of activation and regulation of ANO1-Encoded Ca(2+)-Activated Cl(-) channels
  2. 6182
    “…PURPOSE: Vitamin D (VitD) is a pleiotropic hormone with effects on a multitude of systems and metabolic pathways. Consequently, the relevance of a sufficiently high VitD serum level becomes self-evident. …”
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    A rapid point-of-care assay accurately measures vitamin D
  3. 6183
    “…The human brain is a complex organ that is susceptible to numerous disorders; many of these are caused by genetic changes, but a multitude remain currently unexplained. Understanding NCREs acting during brain development has the potential to shed light on previously unrecognized genetic causes of human brain disease. …”
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    Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance
  4. 6184
    “…BACKGROUND: The zygomaticomaxillary complex (ZMC) can experience a multitude of deforming forces. There is limited understanding on which deformities alter patient outcomes. …”
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    Automated 3D Analysis of Zygomaticomaxillary Fracture Rotation and Displacement
  5. 6185
    “…As a kappa opioid receptor agonist, the antinociceptive effects of nalbuphine in visceral pain are consistent across a multitude of experimental conditions irrespective of species. …”
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    Preemptive Intravenous Nalbuphine for the Treatment of Post-Operative Visceral Pain: A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial
  6. 6186
    “…We identified a 2-cluster solution consisting of two distinct subgroups as best fitting: (1) a CPTSD cluster and (2) a PTSD cluster. The multitude of PMLDs was summarized into four superior factors. …”
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    Complex post-traumatic stress disorder and post-migration living difficulties in traumatised refugees and asylum seekers: the role of language acquisition and barriers
  7. 6187
    “…Liver regeneration is triggered and controlled by a multitude of mitogens acting in autocrine, paracrine, and endocrine ways, with much redundancy and cross-talk between biochemical pathways. …”
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    Liver regeneration biology: Implications for liver tumour therapies
  8. 6188
    “…For each indication, a different set of genes have been identified, revealing that a multitude of factors play a role in the level of gene expression. …”
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    COVID-19 Transcriptomic Atlas: A Comprehensive Analysis of COVID-19 Related Transcriptomics Datasets
  9. 6189
    “…Kaplan–Meier curves were used for graphical presentation. A multitude of patient-specific factors showed a statistical impact in univariate analysis (transfusion, age, gender, diabetes, pT, pN, L, V, Pn, G, UICC, adjuvant therapy, free microvascular transplant, preoperative hemoglobin level). …”
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    Effects of Red Blood Cell Transfusions on Distant Metastases of Oral Squamous Cell Carcinomas
  10. 6190
    “…Variations in PRP products, consequence of the lack of a standardised protocol for the multitude of commercially available blood separation systems and the lack of knowledge of the optimal composition of PRP or its suitability for the proposed indication are some of the reasons behind clinical inconsistencies. …”
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    Age‐based inter‐subject variability in platelet and white blood cell concentrations of platelet‐rich plasma prepared using a new application to blood separation system
  11. 6191
    “…Informal caregivers are inundated by their caregiving responsibilities and resultantly suffer consequences. Despite the multitude of clinical effectiveness studies on interventions that support informal caregivers, there is a paucity of information regarding their implementation process. …”
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    Implementation and dissemination of home and community-based interventions for informal caregivers of people living with dementia: a systematic scoping review protocol
  12. 6192
    “…Purkinje cells (PCs) are large GABAergic projection neurons of the cerebellar cortex, endowed with elaborate dendrites that receive a multitude of excitatory inputs. Being the only efferent neuron of the cerebellar cortex, PCs project to cerebellar nuclei and control behaviors ranging from movement to cognition and social interaction. …”
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    Upregulation of Neural Cell Adhesion Molecule 1 and Excessive Migration of Purkinje Cells in Cerebellar Cortex
  13. 6193
    “…Purpose  Patients with end-stage heart failure who remain symptomatic even with exemplary medical and device therapy are treated with heart transplantation. Multitudes of endeavor have been contrived during the last decennium in the field of noninvasive tests to rule out heart transplant rejection (HTR). …”
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    Insight into Noninvasive Radiological Modalities to Detect Heart Transplant Rejection
  14. 6194
    “…Our observations suggest the existence of a multitude of yet unidentified microbially modified metabolites which pass through the placenta into the fetus and potentially influence fetal development. …”
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    Maternal microbiota-derived metabolic profile in fetal murine intestine, brain and placenta
  15. 6195
    “…Liver transplant (LT) recipients faced a multitude of challenges during the first wave of lockdown. …”
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    Impact of covid-19 pandemic on quality of life and psychosocial difficulties among liver transplant recipients
  16. 6196
    “…The ongoing pandemic resulting from severe acute respiratory syndrome—caused by coronavirus 2 (SARS-CoV-2)—has posed a multitude of healthcare challenges of unprecedented proportions. …”
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    It Ain’t Over 'Til It's Over: SARS CoV-2 and Post-infectious Gastrointestinal Dysmotility
  17. 6197
    “…The mitophagy pathway encompasses diverse mechanisms involving a complex interplay of a multitude of proteins that confers the selective recognition of damaged mitochondria and their targeting to degradation via autophagy. …”
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    Mitophagy and Neurodegeneration: Between the Knowns and the Unknowns
  18. 6198
    “…The Coronavirus disease 2019 (COVID-19) pandemic-caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)– has posed a global threat and presented with it a multitude of economic and public-health challenges. …”
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    SaliVISION: a rapid saliva-based COVID-19 screening and diagnostic test with high sensitivity and specificity
  19. 6199
    “…CONCLUSIONS: Prospective studies among patients with acromegaly and GHD use a multitude of PROMs, often poorly reported. Since a substantial proportion of studies report discrepancies between PROs and biochemical outcomes, PROMs are pivotal in the evaluation of disease activity. …”
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    State of the Art of Patient-reported Outcomes in Acromegaly or GH Deficiency: A Systematic Review and Meta-analysis
  20. 6200
    “…BACKGROUND: Ratoon sugarcane is susceptible to chlorosis, characterized by chlorophyll loss, poor growth, and a multitude of nutritional deficiency mainly occurring at young stage. …”
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    Transcriptome and metabolome analyses reveal new insights into chlorophyll, photosynthesis, metal ion and phenylpropanoids related pathways during sugarcane ratoon chlorosis
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