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6481por Bajeli, Sapna, Baid, Navin, Kaur, Manjot, Pawar, Ganesh P., Chaudhari, Vinod D., Kumar, Ashwani“…However, it can detoxify the reactive oxygen species and facilitate mycobacterial survival during a multitude of stresses. Quinolone derivatives (CK-2-63) and quinone derivative (Aurachin D) inhibit cytochrome bd oxidase. …”
Publicado 2020
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6482por Conte, Gabriella A, Alidoost, Marjan, Devita, Mitchel S, Harmon, Jonathan S, Schuler, Jake W, Brea, Fernando, Farooq, Taliya, Chinnici, Angelo A“…LEARNING POINTS: Malignant aortic tumours are rare and can present with a multitude of symptoms ranging from constitutional symptoms to abdominal discomfort to unexplained hypertension. …”
Publicado 2020
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6483“…Conclusion: Students in this study experience a multitude of stressors during PE lessons. These include stressors in the teaching, physical, and social environments, as well as personal factors. …”
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6484“…Men with type 2 diabetes exhibited altered expression of a multitude of skeletal muscle proteins important for exercise capacity. …”
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6485por Paspala, Anna, Papakonstantinou, Dimitrios, Prodromidou, Anastasia, Danias, Nick, Machairas, Anastasios, Agrogiannis, Georgios, Machairas, Nikolaos, Zavras, Nikolaos J, Patapis, Paulos, Pikoulis, Emmanouil“…Introduction Liver regeneration is an exceptionally complex process, orchestrated by a multitude of growth factors and cytokines. Tumor necrosis factor-alpha (TNF-a) and interleukin-6 (Il-6) have a pivotal role in the initiation of the regenerative response. …”
Publicado 2020
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6486“…PURPOSE OF REVIEW: Giant cell arteritis (GCA), a medium and large vessel vasculitis occurring in the aged, remains a formidable disease, capable of taking both vision and life, through a multitude of vascular complications. Our understanding of the spectrum of its manifestations has grown over the years, to include limb claudication, aortitis, and cardiac disease, in addition to the more classic visual complications resulting from of ischemia to branches of the external and internal carotid arteries. …”
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6487“…Despite their common origin, the Orf7a and Orf8 protein families exhibit different modes of evolutionary trajectories within the coronavirus lineage, which might be partly attributable to their complex interactions with the mammalian host cell, reflected by a multitude of functional associations of Orf8 in SARS-CoV-2 compared to a very small number of interactions discovered for Orf7a.…”
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6488“…These include the task-based methodologies of breath holding and paced deep breathing, as well as a new generation of methods based on spontaneous breathing fluctuations during resting-state. Despite the multitude of alternatives to gas challenges, existing literature lacks definitive conclusions regarding the best practices for the vasoactive modulation and associated analysis protocols. …”
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6489por Stebel, Adam, Urbanová, Wanda, Klimova, Irena, Brudnicki, Andrzej, Dubovska, Ivana, Polackova, Petra, Kroupová, Daniela, Koťová, Magdalena, Fudalej, Piotr S.“…BACKGROUND: There is a multitude of protocols of treatment of cleft lip and palate (CLP) worldwide differing in number of operations, surgical techniques, and timings of surgeries. …”
Publicado 2021
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6490Ceftolozane/Tazobactam Resistance and Mechanisms in Carbapenem-Nonsusceptible Pseudomonas aeruginosapor Teo, Jocelyn Qi-Min, Lim, Jie Chong, Tang, Cheng Yee, Lee, Shannon Jing-Yi, Tan, Si Hui, Sim, James Heng-Chiak, Ong, Rick Twee-Hee, Kwa, Andrea Lay-Hoon“…IMPORTANCE Pseudomonas aeruginosa infection is one of the most difficult health care-associated infections to treat due to the ability of the organism to acquire a multitude of resistance mechanisms and express the multidrug resistance phenotype. …”
Publicado 2021
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6491“…While the mainstay of treatment involves surgically correcting the extrahepatic biliary obstruction via Kasai hepato-portoenterostomy (KHPE), activation of a multitude of biological pathways and yet-to-be-determined etiology in BA continue to foster liver inflammation, cirrhosis and need for LTx. …”
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6492“…By this, cellular IAP1/2, X-linked IAP, Survivin, BRUCE and LIVIN expression/activity, as well as their intracellular localization is controlled by p53 in a direct or indirect manner via modulating a multitude of mechanisms. These cover, among others, transcriptional repression and the signal transducer and activator of transcription (STAT)3 pathway. …”
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6493por Handke, Nikolaus A., Rupp, Alexander B. A., Trimpop, Nicolai, von Pawel, Joachim, Holdenrieder, Stefan“…Background: High mobility group box 1 protein (HMGB1) is known for its significant elevation in a multitude of tumors and benign diseases. In this study, we investigated the relevance of soluble HMGB1 for the prediction and monitoring of therapy response as well as the estimation of prognosis in advanced lung cancer. …”
Publicado 2021
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6494por Fatima, N., Sheikh, N., Satoskar, A. R., Akhtar, T., Tayyeb, A., Ashfaq, I., Ryan, N., Ambreen, S., Jha, B. K., Oghumu, S.“…Tacrolimus (TAC) is an immunosuppressive drug, optimally used for liver, kidney, and heart transplant to avoid immune rejection. In retrospect, a multitude of studies have reported effects of TAC, such as nephrotoxicity, diabetes, and other complications. …”
Publicado 2021
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6495por Grote, Stefan, Traub, Frank, Mittelstaet, Joerg, Seitz, Christian, Kaiser, Andrew, Handgretinger, Rupert, Schleicher, Sabine“…In that process AdCAR NK-92 cells produced a multitude of NK effector molecules as well as pro inflammatory cytokines. …”
Publicado 2021
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6496por Hecht, Jacqueline T, Coustry, Francoise, Veerisetty, Alka C, Hossain, Mohammad G, Posey, Karen L“…Misfolding mutations in cartilage oligomeric matrix protein (COMP) cause it to be retained within the endoplasmic reticulum (ER) of chondrocytes, stimulating a multitude of damaging cellular responses including ER stress, inflammation, and oxidative stress, which ultimately culminates in the death of growth plate chondrocytes and pseudoachondroplasia (PSACH). …”
Publicado 2021
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6497por Kyriakidis, Ioannis, Vasileiou, Eleni, Rossig, Claudia, Roilides, Emmanuel, Groll, Andreas H., Tragiannidis, Athanasios“…Since 1985 when the first agent targeting antigens on the surface of lymphocytes was approved (muromonab-CD3), a multitude of such therapies have been used in children with hematologic malignancies. …”
Publicado 2021
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6498por Paradzik, Tina, Bandini, Cecilia, Mereu, Elisabetta, Labrador, Maria, Taiana, Elisa, Amodio, Nicola, Neri, Antonino, Piva, Roberto“…High-throughput functional approaches are allowing the identification of a multitude of previously undescribed synthetic lethal interactions. …”
Publicado 2021
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6499por Al-Kattan, Ahmed, Grojo, David, Drouet, Christophe, Mouskeftaras, Alexandros, Delaporte, Philippe, Casanova, Adrien, Robin, Jérôme D., Magdinier, Frédérique, Alloncle, Patricia, Constantinescu, Catalin, Motto-Ros, Vincent, Hermann, Jörg“…Third, we address the laser-induced forward transfer, a technology based on direct laser printing, to transfer and assemble a multitude of materials (additive structuring), including biological moiety without alteration of functionality. …”
Publicado 2021
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6500por Xu, Fang, Tian, Lili, Li, Yan, Zhang, Xuelian, Qi, Yayin, Jing, Zhigang, Pan, Yangyang, Zhang, Li, Fan, Xiaoxu, Wang, Meng, Zeng, Qiaoying, Fan, Weixing“…This study aims to investigate the current forms of tuberculosis in cattle and identify the possible transmission modes in dairy farms of China. 13,345 cows from eight dairy farms in three provinces were comprehensively diagnosed by a multitude of assays, including SIT, CIT, IFN-γ assay and ELISA. …”
Publicado 2021
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