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6861“…In the literature, VRI has been utilized in a multitude of clinical and research settings. This systematic review aims to address three study questions relating to whether VRI can be used as an evaluative device, whether the images generated can be characterized, and which tools and measures have been used to assess these images. …”
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6862“…Rate constants of 140 M(−1) s(−1) and ≥1.3 × 10(3) M(−1) s(−1) were estimated, respectively, for the reaction of H(2)O(2) with KEAP1 and with an unknown target that mediates NRF2 protein synthesis. In conclusion, the multitude of H(2)O(2) targets and mechanisms provides an opportunity for highly specific effects on gene regulation that depend on the cell type and on signals received from the cellular microenvironment.…”
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6863Outcomes of Acute Chest Syndrome in Adult Patients with Sickle Cell Disease: Predictors of Mortalitypor Allareddy, Veerajalandhar, Roy, Aparna, Lee, Min Kyeong, Nalliah, Romesh P., Rampa, Sankeerth, Allareddy, Veerasathpurush, Rotta, Alexandre T.“…After adjusting for a multitude of patient and hospital related factors, patients who had MV for <96 hours(OR = 67.53,p<0.01) or those who had MV for ≥96 hours(OR = 8.73,p<0.01) were associated with a significantly higher odds for IHM when compared to their counterparts. …”
Publicado 2014
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6864“…However, its causes are multitude and not uniformly understood enough across the various parts of the world and that a thorough understanding of these causes is required to design appropriate intervention. …”
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6865por Armingohar, Zahra, Jørgensen, Jørgen J., Kristoffersen, Anne Karin, Abesha-Belay, Emnet, Olsen, Ingar“…This indicated that a multitude of bacterial species both from the gut and the oral cavity, rather than exclusively periodontopathogens, may be involved as additional risk factors in the pathogenesis of VD.…”
Publicado 2014
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6866“…Thus, multiple S1P receptors positively and negatively regulate atherosclerosis through multitudes of mechanisms. Considering the essential and multi-faceted role of S1P(2) in atherogenesis and the impact of S1P(2) inactivation on atherosclerosis, S1P(2) is a particularly promising therapeutic target for atherosclerosis.…”
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6867por Oualha, Mehdi, Urien, Saïk, Spreux-Varoquaux, Odile, Bordessoule, Alice, D’Agostino, Irène, Pouard, Philippe, Tréluyer, Jean-Marc“…INTRODUCTION: The response to exogenous epinephrine (Ep) is difficult to predict given the multitude of factors involved such as broad pharmacokinetic and pharmacodynamic between-subject variabilities, which may be more pronounced in children. …”
Publicado 2014
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6868por Reilly, Timothy P., Graziano, Michael J., Janovitz, Evan B., Dorr, Thomas E., Fairchild, Craig, Lee, Francis, Chen, Jian, Wong, Tai, Whaley, Jean M., Tirmenstein, Mark“…Increasing concentrations of glucose, dapagliflozin, or its primary metabolite, dapagliflozin 3-O-glucuronide, did not affect in vitro TCC proliferation rates and dapagliflozin did not enhance tumor growth in nude mice heterotopically implanted with human bladder TCC cell lines. CONCLUSION: A multitude of assessments of tumorigenicity risk consistently showed no effects, suggesting that selective SGLT2 inhibition and, specifically, dapagliflozin are predicted to not be associated with increased cancer risk. …”
Publicado 2014
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6869por Bhinder, Bhavneet, Shum, David, Li, Mu, Ibáñez, Glorymar, Vlassov, Alexander V., Magdaleno, Susan, Djaballah, Hakim“…Focusing primarily on the TRC plasmid-based shRNA hairpins, we reasoned that alleged specificities were perhaps compromised due to altered processing; resulting in a multitude of random interfering sequences. For this purpose, we opted to study the processing of hairpin TRCN#40273 targeting CTTN; which showed activity in a miRNA-21 gain-of-function shRNA screen, but inactive when used as an siRNA duplex. …”
Publicado 2014
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6870por Chinnakali, Palanivel, Upadhyay, Ravi P., Shokeen, Deepa, Singh, Kavita, Kaur, Manpreet, Singh, Arvind K., Goswami, Anil, Yadav, Kapil, Pandav, Chandrakant S.“…Malnutrition is the most serious consequence of food insecurity and has a multitude of health and economic implications. India has the world's largest population living in slums, and these have largely been underserved areas. …”
Publicado 2014
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6871por Tossone, Krystel, Jefferis, Eric, Bhatta, Madhav P, Bilge-Johnson, Sumru, Seifert, Patricia“…CONCLUSIONS: This sample presents with a multitude of issues that contribute to increased odds of revisits to PIRC and inpatient recommendation. …”
Publicado 2014
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6872por Cao, Hongbo, Zhai, Jingbo, Mu, Wei, Lei, Xiang, Cao, Hongxia, Liu, Chunxiang, Shang, Hongcai“…Currently, the existence of a multitude of Chinese patent drugs marked with largely identical indications is further complicating this situation. …”
Publicado 2014
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6873“…BACKGROUND: Fundamental problems faced by the protocells and their modern descendants include how to go from one phenotypic state to another; escape from a basin of attraction in the space of phenotypes; reconcile conflicting growth and survival strategies (and thereby live on ‘the scales of equilibria’); and create a coherent, reproducible phenotype from a multitude of constituents. PRESENTATION OF THE HYPOTHESIS: The solutions to these problems are likely to be found with the organic and inorganic molecules and inorganic ions that constituted protocells, which we term SUMIs for Simple Universal Molecules and Ions. …”
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6874“…A multitude of nanoparticles, such as titanium oxide (TiO(2)), zinc oxide, aluminum oxide, gold oxide, silver oxide, iron oxide, and silica oxide, are found in many chemical, cosmetic, pharmaceutical, and electronic products. …”
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6875por Venkatesan, Aravind, Tripathi, Sushil, Sanz de Galdeano, Alejandro, Blondé, Ward, Lægreid, Astrid, Mironov, Vladimir, Kuiper, Martin“…The background information required for the construction of such networks is often dispersed across a multitude of knowledge bases in a variety of formats. …”
Publicado 2014
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6876“…BACKGROUND: In most biological experiments, especially infectious disease, the exposure-response relationship is interrelated by a multitude of factors rather than many independent factors. …”
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6877por Schäfer, Ingmar, Kaduszkiewicz, Hanna, Wagner, Hans-Otto, Schön, Gerhard, Scherer, Martin, van den Bussche, Hendrik“…In females, depression was also associated with many other diseases. We found a multitude of associations between disorders of the metabolic syndrome of which hypertension was the most central disease. …”
Publicado 2014
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6878High Risk of Under-Grading and -Staging in Prostate Cancer Patients Eligible for Active Surveillancepor Heidegger, Isabel, Skradski, Viktor, Steiner, Eberhard, Klocker, Helmut, Pichler, Renate, Pircher, Andreas, Horninger, Wolfgang, Bektic, Jasmin“…CONCLUSION: In summary, this study shows that a multitude of patients fulfilling the criteria for AS are under-diagnosed. …”
Publicado 2015
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6879por Abdelmagid, Salma A., Clarke, Shannon E., Nielsen, Daiva E., Badawi, Alaa, El-Sohemy, Ahmed, Mutch, David M., Ma, David W. L.“…Circulating fatty acids (FA) are associated with a multitude of chronic diseases. However, a major gap in establishing such relationships is the lack of accepted fatty acid reference ranges representing healthy individuals. …”
Publicado 2015
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6880“…Marine bacteria have so far not been exploited to the same extent; however, they are believed to harbor a multitude of novel bioactive chemistry. To explore this potential, genomes of 21 marine Alpha- and Gammaproteobacteria collected during the Galathea 3 expedition were sequenced and mined for natural product encoding gene clusters. …”
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