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7501“…The title compounds were broken into small fragment ions under the pyrolysis conditions, which then might undergo a multitude of collisions and numerous other reactions, resulting in the formation of C(2)N(2) (m/z 52), etc., before being analyzed by the GC/MS system. …”
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7502por Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E., Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R.“…BACKGROUND: Huntington Disease (HD) is an incurable autosomal dominant neurodegenerative disorder driven by an expansion repeat giving rise to the mutant huntingtin protein (mHtt), which is known to disrupt a multitude of transcriptional pathways. Pridopidine, a small molecule in development for treatment of HD, has been shown to improve motor symptoms in HD patients. …”
Publicado 2018
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7503por Zhang, Chen, Grandits, Thomas, Härenstam, Karin Pukk, Hauge, Jannicke Baalsrud, Meijer, Sebastiaan“…Such professionals perform coordinating functions by managing the timing and execution of a multitude of care processes for multiple patients. …”
Publicado 2018
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7504por Feng, Zhiqiang, Zhou, Jie, Shang, Xueying, Kuang, Guojun, Han, Jian, Lu, Liping, Zhang, Lei“…Context: Baicalin (BL) and baicalein (B) as the major flavonoids of Scutellaria baicalensis Georgi (Lamiaceae) have been investigated intensively, and shown to possess a multitude of pharmacological activities. Objective: This study systematically evaluates the stability of BL and B in monomer and total flavonoid fraction (FSR) form in vitro, and further studies whether the protective measures are effective to make B and BL stable enough to meet the requirement of quantitative analysis in various biological samples. …”
Publicado 2017
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7505por Jha, Ayan, Lin, Leesa, Short, Sarah Massin, Argentini, Giorgia, Gamhewage, Gaya, Savoia, Elena“…To facilitate an accurate identification of the gaps, the authors suggest integrating current findings with case studies across the WHO regions to better understand the specific evidence that is needed in practice across the multitude of ERC functions.…”
Publicado 2018
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7506por Starlinger, Johannes, Pallarz, Steffen, Ševa, Jurica, Rieke, Damian, Sers, Christine, Keilholz, Ulrich, Leser, Ulf“…In practice, collecting such comprehensive information on genomic variants is difficult since the underlying data is dispersed over a multitude of distributed, heterogeneous, sometimes conflicting, and quickly evolving data sources. …”
Publicado 2018
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7507“…BACKGROUND: Relatives of people experiencing bipolar mood episodes or psychosis face a multitude of challenges (eg, social isolation, limited coping strategies, and issues with maintaining relationships). …”
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7508por Bejerot, Susanne, Hesselmark, Eva, Mobarrez, Fariborz, Wallén, Håkan, Hietala, Max Albert, Nybom, Rolf, Wetterberg, Lennart“…At age 22, she had a multitude of motor and psychiatric symptoms. Over the years, she fulfilled the diagnostic criteria for anorexia nervosa, depression, sleep disorder, obsessive-compulsive disorder, generalized anxiety disorder, panic disorder, agoraphobia, social anxiety disorder, development coordination disorder, attention-deficit/hyperactivity disorder, hypomania, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, conversion disorder, psychosis, and schizotypal personality syndrome. …”
Publicado 2019
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7509“…BACKGROUND: A multitude of recent studies has observed common epigenetic changes develop in tumour cells of multiple lineages following exposure to stresses such as hypoxia, chemotherapeutics, immunotherapy or targeted therapies. …”
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7510“…These heme-containing enzymes typically catalyze the oxidation of unactivated C–H and C=C bonds in a multitude of substrates, often with complete regio- and stereospecificity. …”
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7511“…Otherwise, in a patient so profoundly immunosuppressed by endogenous steroids, a multitude of fungi and other atypical infections which are difficult to detect, need be considered when sepsis develops in association with chemotherapy.…”
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7512por Brandner, Juergen J.“…NMR is currently undergoing a tremendous change from large-scale to benchtop measurement systems, and it will most likely be further miniaturized. NMR allows a multitude of different measurements, which are normally covered by several instruments. …”
Publicado 2019
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7513por Mannapperuma, Uthpali, Galappatthy, Priyadarshani, Jayakody, Raveendra Laal, Mendis, Jayan, de Silva, Varuni Asanka, Hanwella, Raveen“…ISBD standards are difficult to achieve in resource limited settings due to a multitude of reasons. Realistic monitoring benchmarks and recommendations are proposed for methods to improve monitoring in resource limited settings based on our experience.…”
Publicado 2019
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7514por Arbelaez, Juan David, Dwiyanti, Maria Stefanie, Tandayu, Erwin, Llantada, Krizzel, Jarana, Annalhea, Ignacio, John Carlos, Platten, John Damien, Cobb, Joshua, Rutkoski, Jessica Elaine, Thomson, Michael J., Kretzschmar, Tobias“…BACKGROUND: While a multitude of genotyping platforms have been developed for rice, the majority of them have not been optimized for breeding where cost, turnaround time, throughput and ease of use, relative to density and informativeness are critical parameters of their utility. …”
Publicado 2019
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7515por Selich, Anton, Zimmermann, Katharina, Tenspolde, Michel, Dittrich-Breiholz, Oliver, von Kaisenberg, Constantin, Schambach, Axel, Rothe, Michael“…However, upon activation with TNF-α and IFN-γ, cells from both induction time points produced a multitude of immunomodulatory cytokines. Interestingly, the later induced MSC-EMs produced higher amounts of cytokines. …”
Publicado 2019
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7516“…BACKGROUND: Los Angeles (LA) County is large and diverse urban southern California county with a population of over 10 million and a multitude of hospitals. The state of California required hospitals to implement ASPs in July 2015. …”
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7517por Udhaya Kumar, S., Thirumal Kumar, D., Siva, R., George Priya Doss, C., Younes, Salma, Younes, Nadin, Sidenna, Mariem, Zayed, Hatem“…Our integrative analysis using a multitude of bioinformatics tools might promote an understanding of the dysregulated pathways that are associated with SLE development and progression. …”
Publicado 2020
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7518“…Majority of patients with pre-existing diabetes required intensification of their medications for diabetes to achieve optimal glycemic control. Discussion A multitude of factors including type of transplant, individual pre-operative metabolic profiles, choice of immunosuppressive agents and certain infections increase the risk of these metabolic complications. …”
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7519por Peine, Arne, Paffenholz, Pia, Martin, Lukas, Dohmen, Sandra, Marx, Gernot, Loosen, Sven H“…BACKGROUND: In an effort to contain the effects of the coronavirus disease (COVID-19) pandemic, health care systems worldwide implemented telemedical solutions to overcome staffing, technical, and infrastructural limitations. In Germany, a multitude of telemedical systems are already being used, while new approaches are rapidly being developed in response to the crisis. …”
Publicado 2020
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7520por Brito, Luiz F., Oliveira, Hinayah R., McConn, Betty R., Schinckel, Allan P., Arrazola, Aitor, Marchant-Forde, Jeremy N., Johnson, Jay S.“…Efficient implementation of genetic and genomic selection for improved animal welfare also requires the integration of a multitude of scientific fields such as cell and molecular biology, neuroscience, immunology, stress physiology, computer science, engineering, quantitative genomics, and bioinformatics.…”
Publicado 2020
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