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  1. 801
    por Kourra, C. M. B. K., Cramer, N.
    Publicado 2016
    “…The developed protocol is applicable to a range of peptides and selective in the presence of a multitude of potentially reactive functional groups. …”
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    Converting disulfide bridges in native peptides to stable methylene thioacetals
  2. 802
    “…In vertebrates, the functions of both motile and immotile cilia are critical for embryonic development and adult tissue homeostasis. Importantly, a multitude of human diseases is caused by abnormal cilia biogenesis and functions which rely on the compartmentalization of the cilium and the maintenance of its protein composition. …”
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    The Ciliary Transition Zone: Finding the Pieces and Assembling the Gate
  3. 803
    por Lemmens, Pieter
    Publicado 2015
    “…In this reply I try to show that, contrary to Milberry’s apparent assertion, the general intellect of the multitude does not have the explanatory robustness she accredits to it (following both Virno and the Hardt and Negri of the Empire trilogy). …”
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    Love and Realism
  4. 804
    “…A software package for the calibration and processing of powder X-ray diffraction and small-angle X-ray scattering data is presented. It provides a multitude of data processing and visualization tools as well as a command-line scripting interface for on-the-fly processing and the incorporation of complex data treatment tasks. …”
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    Processing two-dimensional X-ray diffraction and small-angle scattering data in DAWN 2
  5. 805
    por Postel, Hannah
    Publicado 2017
    “…While the growing Chinese presence in Africa is often viewed as a coherent neocolonialist strategy planned and implemented by the Chinese state, this paper demonstrates that it is in fact typified by a multitude of both public and private actors with independent motives.…”
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    Moving Beyond “China in Africa”: Insights from Zambian Immigration Data
  6. 806
    “…RNA editing can generate a multitude of transcript isoforms and can potentially be used to optimize protein function in response to varying conditions. …”
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    The evolution and adaptation of A-to-I RNA editing
  7. 807
    “…Evidence from many recent studies indicates that the circadian clock regulates a multitude of factors that affect plant metabolites, especially emitted volatiles that have important ecological functions. …”
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    Regulation of the Rhythmic Emission of Plant Volatiles by the Circadian Clock
  8. 808
    “…Over the last decade, several mechanisms have been identified to decipher the emergence of resistance. There is a multitude of changes within the tumor microenvironment (TME) in response to anti-angiogenic therapy that offers new therapeutic opportunities. …”
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    The role of tumor microenvironment in resistance to anti-angiogenic therapy
  9. 809
    por Young, M. Rita I.
    Publicado 2017
    “…Among the challenges of immunotherapeutic approaches for cancer are the multitudes of mechanisms by which cancers are known to subvert the immune defenses. …”
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    Redirecting the focus of cancer immunotherapy to premalignant conditions
  10. 810
    “…Clinical and imaging findings are nebulous as the intravascular subtype of lymphoma can involve a multitude of organs. Involvement of the gallbladder is extremely uncommon, and imaging findings can be easily confused for more prevalent pathologies. …”
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    Intravascular Large B-Cell Lymphoma Presenting with Diffuse Gallbladder Wall Thickening: A Case Report and Literature Review
  11. 811
    “…A major challenge in teaching and popularizing microbiology is to provide students and the general public with a varied understanding of microbes in nature to reinforce their importance in a multitude of processes. In this perspective article, I discuss the persistence of the association between microbes and disease in laypersons’ views. …”
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    Towards an Evolutionary Perspective in Teaching and Popularizing Microbiology
  12. 812
    por Sharma, Sumana, Petsalaki, Evangelia
    Publicado 2018
    “…The cellular signalling process is a highly complex mechanism, involving multiple players, which together orchestrate the cell’s response to environmental changes and perturbations. Given the multitude of genes that participate in the process of cellular signalling, its study in a genome-wide manner has proven challenging. …”
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    Application of CRISPR-Cas9 Based Genome-Wide Screening Approaches to Study Cellular Signalling Mechanisms
  13. 813
    “…Skeletal muscle-derived PW1(pos)/Pax7(neg) interstitial cells (PICs) express and secrete a multitude of proregenerative growth factors and cytokines. …”
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    Transplantation of Allogeneic PW1(pos)/Pax7(neg) Interstitial Cells Enhance Endogenous Repair of Injured Porcine Skeletal Muscle
  14. 814
    “…This viewpoint is built on the “hub” nature of the 14-3-3 proteins, binding to several hundred identified partners, consequently implicating them in a multitude of different cellular mechanisms. In this review, we provide an overview of the structural and biological features of 14-3-3 and the modulation of 14-3-3 PPIs for discovering small molecular inhibitors and stabilizers of 14-3-3 PPIs.…”
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    14-3-3: A Case Study in PPI Modulation
  15. 815
    “…Osteoblasts/osteocytes and osteoclasts dominate the metabolism of bone by a multitude of connections. Therefore, it is widely accepted that a constant improvement of co-culture models with both cell types cultured on a 3D scaffold, is aimed to mimic an in vivo environment as closely as possible. …”
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    From the Clinical Problem to the Basic Research—Co-Culture Models of Osteoblasts and Osteoclasts
  16. 816
    “…Immunosenescence that occurs with aging, however, compromises the ability of CD4(+) T cells to differentiate into functional subsets resulting in a multitude of dysregulated responses namely, delayed viral clearance and prolonged inflammation leading to increased pathology. …”
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    The impact of aging on CD4(+) T cell responses to influenza infection
  17. 817
    “…The overall goal of this study is to critically assess this ability of a variety of heterogeneous ensemble methods across a multitude of functional terms, proteins and organisms. …”
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    Large-scale protein function prediction using heterogeneous ensembles
  18. 818
    “…[Image: see text] Visible-light-promoted organic reactions can offer increased reactivity and selectivity via unique reaction pathways to address a multitude of practical synthetic problems, yet few practical solutions exist to employ these reactions for multikilogram production. …”
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    A Laser Driven Flow Chemistry Platform for Scaling Photochemical Reactions with Visible Light
  19. 819
    “…The purpose of this review is to summarize the peculiarities of the presently available breast cancer exosomal biomarkers; the review also provides the prediction of a multitude of potential target genes of exosomal microRNAs using 4 databases.…”
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    Exosomes: A Promising Avenue for the Diagnosis of Breast Cancer
  20. 820
    “…In 2008, the FDA suggested that CVD risk should be evaluated for any new antidiabetic therapy, leading to a multitude of large CVD outcome trials to assess CVD risk from these medications. …”
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    The effect of sodium‐glucose cotransporter 2 inhibitors and glucagon‐like peptide 1 agonists on cardiovascular disease in patients with type 2 diabetes
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