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  1. 1001
    “…Amino acids play fundamental roles in a multitude of functions including protein synthesis, hormone metabolism, nerve transmission, cell growth, production of metabolic energy, nucleobase synthesis, nitrogen metabolism, and urea biosynthesis. …”
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    Amino Acid Transporter Inventory of the Selaginella Genome
  2. 1002
    por Behne, Tara, Copur, M. Sitki
    Publicado 2012
    “…Increased understanding of cancer biology and technological advances have enabled identification of a multitude of pathological, genetic, and molecular events that drive hepatocarcinogenesis leading to discovery of numerous potential biomarkers in this disease. …”
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    Biomarkers for Hepatocellular Carcinoma
  3. 1003
    “…A detailed understanding of the structure of the cerebrovascular system is important for a multitude of (patho-)physiological cerebral processes and many noninvasive functional imaging methods rely on a signal that originates from the vasculature. …”
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    Topology and hemodynamics of the cortical cerebrovascular system
  4. 1004
    “…Measurement of insulin-like growth factor-1 (IGF-I) has utility for the diagnosis and management of growth disorders, but inter-assay comparison of results has been complicated by a multitude of reference standards, antibodies, detection methods, and pre-analytical preparation strategies. …”
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    Clinical Utility of Insulin-Like Growth Factor 1 and 2; Determination by High Resolution Mass Spectrometry
  5. 1005
    “…PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants. PIN localization is under extensive control by environmental or developmental cues, but mechanisms regulating PIN localization are not fully understood. …”
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    Cell Polarity and Patterning by PIN Trafficking through Early Endosomal Compartments in Arabidopsis thaliana
  6. 1006
    “…A particular focus has been placed on the multitude of signaling cascades linked to the condition as these are viewed as having the greatest therapeutic potential. …”
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    Is There a Role for Treating Inflammation in Moyamoya Disease?: A Review of Histopathology, Genetics, and Signaling Cascades
  7. 1007
    “…Lipid bilayer membranes are among the most ubiquitous structures in the living world, with intricate structural features and a multitude of biological functions. It is attractive to recreate these structures in the laboratory, as this allows mimicking and studying the properties of biomembranes and their constituents, and to specifically exploit the intrinsic two-dimensional fluidity. …”
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    Lab on a Biomembrane: Rapid prototyping and manipulation of 2D fluidic lipid bilayers circuits
  8. 1008
    “…In this review, a selective survey of the multitude of functions of presenilins and the γ-secretase complex is presented. …”
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    The very many faces of presenilins and the γ-secretase complex
  9. 1009
    por Vagholkar, Ketan, Dastoor, Khojasteh
    Publicado 2013
    “…Anomalies of the ribs, spine, and muscles which constitute the lumbocostovertebral syndrome in association with congenital lumbar hernia make it the rarest of entities. In addition, a multitude of other organ systems may be involved. Case Report. …”
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    Congenital Lumbar Hernia with Lumbocostovertebral Syndrome: A Case Report and Review of the Literature
  10. 1010
    “…ARC is subject to both transcriptional and post-translational regulation and exhibits its function through a multitude of molecular interactions with upstream transducers of apoptosis signals. …”
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    Apoptosis repressor with caspase recruitment domain, a multifunctional modulator of cell death
  11. 1011
    “…Based on the comprehensive analysis of these datasets by a wide array of modern bioinformatics tools it was concluded that disordered regions of PCD-related proteins are involved in a multitude of biological functions and interactions with various partners, possess numerous posttranslational modification sites, and have specific evolutionary patterns (Peng et al. 2013). …”
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    On the intrinsic disorder status of the major players in programmed cell death pathways
  12. 1012
    “…The environmental persistence of V. cholerae in the aquatic environment can be attributed to multiple intra- and interspecific strategies such as responsive gene regulation and biofilm formation on biotic and abiotic surfaces, as well as interactions with a multitude of other organisms. This review will discuss some of the mechanisms that enable the persistence of this bacterium in the environment. …”
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    Environmental reservoirs and mechanisms of persistence of Vibrio cholerae
  13. 1013
    por Schroll, Henning, Hamker, Fred H.
    Publicado 2013
    “…Most of these models implement multiple distinct basal-ganglia pathways and assume them to fulfill different functions. As there is now a multitude of different models, it has become complex to keep track of their various, sometimes just marginally different assumptions on pathway functions. …”
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    Computational models of basal-ganglia pathway functions: focus on functional neuroanatomy
  14. 1014
    por Ramjee, Gita, Daniels, Brodie
    Publicado 2013
    “…Epidemiological evidence suggests unacceptably high HIV prevalence and incidence rates among women. A multitude of factors increase women’s vulnerability to HIV acquisition, including, biological, behavioral, socioeconomic, cultural and structural risks. …”
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    Women and HIV in Sub-Saharan Africa
  15. 1015
    “…Luman is implicated in a multitude of functions ranging from viral infection and immunity to cancer. …”
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    Expression Pattern Implicates a Potential Role for Luman Recruitment Factor in the Process of Implantation in Uteri and Development of Preimplantation Embryos in Mice
  16. 1016
    “…For many years, the battle between humans and the multitudes of infection and disease causing pathogens continues. …”
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    Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance
  17. 1017
    “…They share the same structural features, arranged in a seemingly simple fold, but they perform a multitude of functions in oxidative protein folding and electron transfer pathways. …”
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    An Extended Active-site Motif Controls the Reactivity of the Thioredoxin Fold
  18. 1018
    “…Taken together this tells us that it is possible for a multitude of different mechanisms to underlie the same STP pattern, even though some are more important in specific cases, and that mechanistic models can be used to integrate the biophysical properties to see which mechanisms are more important in specific cases of STP.…”
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    Biophysical properties of presynaptic short-term plasticity in hippocampal neurons: insights from electrophysiology, imaging and mechanistic models
  19. 1019
    “…Following myocardial infarction (MI), a multitude of ECM proteins are synthesized to replace myocyte loss and form a reparative scar. …”
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    Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling
  20. 1020
    “…In particular, we review the role of the glucocorticoid receptor, the main mediator of the stress response in the proliferation, differentiation, migration, and functional integration of newborn neurons in the hippocampus. We review a multitude of mechanisms regulating glucocorticoid receptor activity in relationship to adult neurogenesis. …”
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    Stress, glucocorticoid receptors, and adult neurogenesis: a balance between excitation and inhibition?
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