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  1. 1021
    “…However, intronic control over gene expression is governed by a multitude of complex, incompletely understood, regulatory mechanisms. …”
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    Accurate, Model-Based Tuning of Synthetic Gene Expression Using Introns in S. cerevisiae
  2. 1022
    “…Treatment outcomes are dictated by a multitude of factors, including stage at diagnosis, tissue type, and overall health of the patient. …”
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    Phytochemicals: A Multitargeted Approach to Gynecologic Cancer Therapy
  3. 1023
    “…As with most physical activity, the regulation of pacing in triathlon may be influenced by a multitude of intrinsic and extrinsic factors. The majority of current research focuses mainly on the Olympic distance, whilst much less literature is available on other triathlon distances such as the sprint, half-Ironman, and Ironman distances. …”
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    Factors influencing pacing in triathlon
  4. 1024
    “…These early events are critical for producing a pool of multipotent cells capable of giving rise to the multitude of neurons and glia that form the central nervous system. …”
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    Neural Transcription Factors: from Embryos to Neural Stem Cells
  5. 1025
    por Spivakov, Mikhail
    Publicado 2014
    “…Transcription factor binding sites (TFBSs) on the DNA are generally accepted as the key nodes of gene control. However, the multitudes of TFBSs identified in genome-wide studies, some of them seemingly unconstrained in evolution, have prompted the view that in many cases TF binding may serve no biological function. …”
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    Spurious transcription factor binding: Non-functional or genetically redundant?
  6. 1026
    “…The limitations of spirometry and clinical history have prompted researchers to investigate a multitude of surrogate biomarkers of disease for the assessment of patients, prediction of risk, and guidance of treatment. …”
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    Surfactant protein D, Club cell protein 16, Pulmonary and activation-regulated chemokine, C-reactive protein, and Fibrinogen biomarker variation in chronic obstructive lung disease
  7. 1027
    “…The eventual widespread clinical adoption of this non-invasive therapeutic modality require continued progress, in a multitude of activities including technical, pre-clinical, and clinical research, regulatory approval and reimbursement, manufacturer growth, and other commercial and public sector investments into the field, all within a multi-stakeholder environment. …”
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    Focused ultrasound development and clinical adoption: 2013 update on the growth of the field
  8. 1028
    por Ma, Cheng, Xu, Xiao, Liu, Yan, Wang, Lihong V.
    Publicado 2014
    “…The ability to steer and focus light inside scattering media has long been sought for a multitude of applications. To form optical foci inside scattering media, the only feasible strategy at present is to guide photons by using either implanted(1) or virtual(2–4) guide stars, which can be inconvenient and limits potential applications. …”
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    Time-reversed adapted-perturbation (TRAP) optical focusing onto dynamic objects inside scattering media
  9. 1029
    por Yap, Chan Choo, Winckler, Bettina
    Publicado 2015
    “…Proper cortical development depends on the orchestrated actions of a multitude of guidance receptors and adhesion molecules and their downstream signaling. …”
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    Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development
  10. 1030
    “…Microbial life on plant leaves is characterized by a multitude of interactions between leaf colonizers and their environment. …”
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    Spatial scales of interactions among bacteria and between bacteria and the leaf surface
  11. 1031
    “…The use of PR strategies should be based on the patient’s goals after a thorough explanation of realistic expectations, and the risks and consequences of the various treatment options. While a multitude of studies suggest a benefit with PR strategies, there are no established, proven regimens. …”
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    Current penile-rehabilitation strategies: Clinical evidence
  12. 1032
    “…Modern medicinal plant drug discovery has provided pharmacologically active compounds targeted against a multitude of conditions and diseases, such as infection, inflammation, and cancer. …”
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    Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division
  13. 1033
    “…The efficacy of therapies that either directly introduce or stimulate local production of growth factors and their receptors in damaged brain tissue has been tested in a multitude of models for different Central Nervous System (CNS) diseases. …”
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    Growth Factors for the Treatment of Ischemic Brain Injury (Growth Factor Treatment)
  14. 1034
    por Idris, Adi, Ghazali, Nur B, Koh, David
    Publicado 2015
    “…Decades of work has shown to us that cancer progression is influenced by a multitude of factors, including genetic, environmental, and immunological factors. …”
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    Interleukin 1β—A Potential Salivary Biomarker for Cancer Progression?
  15. 1035
    “…Although there are a multitude of advanced toolboxes for investigating resting-state functional connectivity, BASCO is the first toolbox for evaluating task-related whole-brain functional connectivity employing a large number of network nodes. …”
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    BASCO: a toolbox for task-related functional connectivity
  16. 1036
    “…We also demonstrate active control and customization of the programming characteristics of the device that reliably realize a multitude of resistance states.…”
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    Projected phase-change memory devices
  17. 1037
    “…In spite of that they presented with mainly laryngeal symptoms and a multitude of findings on laryngeal examination. A diagnosis could be established owing to a high index of clinical suspicion, and due consideration given to the chest findings and positive sputum examination. …”
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    Secondary laryngeal tuberculosis revisited
  18. 1038
    “…The mammalian/mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that integrates a multitude of extracellular signals and intracellular cues to drive growth and proliferation. mTOR activity is altered in numerous pathological conditions, including metabolic syndrome and cancer. …”
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    mTOR coordinates protein synthesis, mitochondrial activity and proliferation
  19. 1039
    “…This cognitive disorder associated with a multitude of clinical differentials with overlapping clinical, pathological, and imaging features is difficult to diagnose and treat, as it often presents late after significant neuronal damage has already occurred. …”
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    Integrated (18)F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging ((18)F-FDG PET/MRI), a multimodality approach for comprehensive evaluation of dementia patients: A pictorial essay
  20. 1040
    por Proserpio, Valentina, Mahata, Bidesh
    Publicado 2015
    “…The immune system is composed of a variety of cells that act in a coordinated fashion to protect the organism against a multitude of different pathogens. The great variability of existing pathogens corresponds to a similar high heterogeneity of the immune cells. …”
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    Single‐cell technologies to study the immune system
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