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1381por Zotti, Linda A., Bednarz, Beatrice, Hurtado-Gallego, Juan, Cabosart, Damien, Rubio-Bollinger, Gabino, Agrait, Nicolas, van der Zant, Herre S.J.“…Ab initio calculations revealed that the observed broad conductance distribution stems from the possibility of various binding geometries which can be formed during stretching combined with a multitude of possible conformational changes. The results suggest that it would be helpful to explore different experimental techniques such as recognition tunneling and conditions to help identify the nature of amino-acid-based junctions even further, for example, with the goal to establish a firm platform for their unambiguous recognition by tunneling break-junction experiments.…”
Publicado 2019
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1382“…We validate Chicdiff on published Promoter Capture Hi-C data in human Monocytes and CD4(+) T cells, identifying multitudes of cell type-specific interactions, and confirming the overall positive association between promoter interactions and gene expression. …”
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1383“…The differential diagnosis for hoarseness is extensive and includes a multitude of etiologies that span a large geographic area from the brainstem to the mediastinum. …”
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1384“…De novo protein synthesis by the ribosome and its multitude of co-factors must occur in a tightly regulated manner to ensure that the correct proteins are produced accurately at the right time and, in some cases, also in the proper location. …”
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1385“…Objects in a scene can be distinct from one another along a multitude of visual attributes, such as color and shape, and the more distinct an object is from its surroundings, the easier it is to find it. …”
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1386“…Gastric outlet obstruction is known complication of acids and surgery is the mainstay of treatment. There are multitude of surgical options for these strictures depending on the involved segment of the stomach and experience of the surgeon. …”
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1387por Duschmalé, Jörg, Hansen, Henrik Frydenlund, Duschmalé, Martina, Koller, Erich, Albaek, Nanna, Møller, Marianne Ravn, Jensen, Klaus, Koch, Troels, Wengel, Jesper, Bleicher, Konrad“…Thus PS oligonucleotides are generally obtained as an inseparable mixture of a multitude of diastereoisomeric compounds. Herein, we describe the introduction of non-chiral 3′ thiophosphate linkages into antisense oligonucleotides and report their in vitro as well as in vivo activity. …”
Publicado 2020
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1388“…The results from these studies have identified a multitude of shear stress-regulated molecular networks in the endothelium that are implicated in health and disease. …”
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1389“…Differentiation of OLs from oligodendrocyte progenitor cells (OPCs) is orchestrated by a multitude of intrinsic and extrinsic factors in the CNS. …”
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1390“…Most crucial is the contribution of platelets to the formation and expansion of the early metastatic niche, a protective microenvironment that nurtures the first metastatic cells and is necessary for the establishment of overt metastatic disease. A multitude of mechanisms have been proposed toward this effect. …”
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1391por Zeiß, Steeven, Marinc, Alexander, Braun, Andreas, Große-Puppendahl, Tobias, Beck, Sebastian“…In public places sanitary conditions are always of concern, particularly of surfaces that are touched by a multitude of persons, such as door handles in rest rooms. …”
Publicado 2014
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1392“…We show that tobacco is a robust biological reactor with a multitude of applications and may hold the key to success in plant molecular farming.…”
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1393“…OAds have been used as promising cancer gene therapies for many years and there are a multitude of encouraging pre-clinical studies. However, translating OAd therapies to the clinic has had limited success, in part due to the lack of realistic pre-clinical models to rigorously test the efficacy of OAds. …”
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1394por Schultz, Daniel, Surabhi, Surabhi, Stelling, Nicolas, Rothe, Michael, Methling, Karen, Hammerschmidt, Sven, Siemens, Nikolai, Lalk, Michael“…In this study, we assess, for the first time, the different intracellular profiles of these bioactive lipid mediators during S. aureus LUG2012, S. pneumoniae TIGR4, IAV, and corresponding viral and bacterial co-infections of 16HBE cells. We observed a multitude of altered lipid mediators. Changes in the amount of 5-hydroxyeicosatetraenoic acid (5-HETE) were prominent for all bacterial infections. …”
Publicado 2020
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1395por Chen, Jennifer M., Al, Kait F., Craven, Laura J., Seney, Shannon, Coons, Margaret, McCormick, Heather, Reid, Gregor, O’Connor, Colleen, Burton, Jeremy P.“…Fermentation has been applied to a multitude of food types for preservation and product enhancing characteristics. …”
Publicado 2020
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1396por Teubner, Marlene, Lenzen, Benjamin, Espenberger, Lucas Bernal, Fuss, Janina, Nickelsen, Jörg, Krause, Kirsten, Ruwe, Hannes, Schmitz-Linneweber, Christian“…Chloroplast RNAs are stabilized and processed by a multitude of nuclear-encoded RNA-binding proteins, often in response to external stimuli like light and temperature. …”
Publicado 2020
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1397por Harding, Simon D., Faccenda, Elena, Southan, Christopher, Pawson, Adam J., Maffia, Pasquale, Alexander, Stephen P. H., Davenport, Anthony P., Fabbro, Doriano, Levi‐Schaffer, Francesca, Spedding, Michael, Davies, Jamie A.“…Given the critical role that the immune system plays in a multitude of diseases, having a clear understanding of the pharmacology of the immune system is crucial to new drug discovery and development. …”
Publicado 2020
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1398por Belz, Gabrielle T.“…In this process, it has uncovered a multitude of cell types that bridge the innate and adaptive arms of the immune system—blurring the line between these two branches—and ultimately fortifying the development of long-term immune protection.…”
Publicado 2020
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1399“…The bone marrow niche is a complex and dynamic structure composed of a multitude of cell types which functionally create an interactive network facilitating hematopoietic stem cell development and maintenance. …”
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1400por Görgülü, Kıvanç, Diakopoulos, Kalliope N., Kaya-Aksoy, Ezgi, Ciecielski, Katrin J., Ai, Jiaoyu, Lesina, Marina, Algül, Hana“…Autophagy occurs in several compartments of pancreatic cancer tissue including cancer cells, cancer associated fibroblasts, and immune cells where it can be subjected to a multitude of stimulatory and inhibitory signals fine-tuning its activity. …”
Publicado 2020
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