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1761“…The advent of tyrosine kinase inhibitors (TKIs) has led to marked improvements in responses and overall survival; however, there is still a subset of patients that are either resistant through a multitude of mechanisms or intolerant to standard TKI therapy. …”
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1762“…Patients with Wolff-Parkinson-White syndrome may present with a multitude of symptoms such as unexplained anxiety, palpitations, fatigue, light-headedness or dizziness, loss of consciousness, and shortness of breath. …”
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1763“…Here, our bioeconomic analysis considers the multitude of factors that influence coffee production. …”
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1764“…Numerous investigations have revealed a multitude of individual cell-cell interactions important for this self-organisation, but it has remained unclear whether these known biological rules were sufficient to explain pattern formation. …”
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1765“…These viruses are quite diverse, some containing mono- or bi-partite genomes, and infecting a multitude of monocot and dicot plants. There are currently many efforts directed at controlling these diseases. …”
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1766“…It has been associated with a multitude of severe infectious complications, such as hepatitis B, hepatitis C, human immunodeficiency virus, and endocarditis, though others such as skin and soft tissue infections are also extremely common. …”
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1767por Domínguez, Marisol, Dugas, Elise, Benchouaia, Médine, Leduque, Basile, Jiménez-Gómez, José M, Colot, Vincent, Quadrana, Leandro“…Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. …”
Publicado 2020
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1768por Baggiani, Matteo, Dell’Anno, Maria Teresa, Pistello, Mauro, Conti, Luciano, Onorati, Marco“…Building and functioning of the human brain requires the precise orchestration and execution of myriad molecular and cellular processes, across a multitude of cell types and over an extended period of time. …”
Publicado 2020
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1769“…BACKGROUND: Minimally invasive techniques have increasingly found their way into liver surgery in recent years. A multitude of mostly retrospective analyses suggests several advantages of laparoscopic over open liver surgery. …”
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1770por Tortora, Carola, Mai, Christina, Cascella, Francesca, Mauksch, Michael, Seidel‐Morgenstern, Andreas, Lorenz, Heike, Tsogoeva, Svetlana B.“…Racemization by enolization was computationally found to dominate, both under water‐free conditions and in presence of water, involving a multitude of different pathways. Faster racemization in presence of water resulted indeed in more rapid deracemization, when the base was pyrrolidine. …”
Publicado 2020
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1771por Seifert, Georg J.“…The sub-family of arabinogalactan proteins is implicated in a multitude of biological functions, however, the mechanistic role of O-glycosylation on AGPs by type II arabinogalactans is largely elusive. …”
Publicado 2020
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1772por Jashnsaz, Hossein, Fox, Zachary R., Hughes, Jason J., Li, Guoliang, Munsky, Brian, Neuert, Gregor“…To demonstrate our approach, we use experimentally identified models to predict signaling dynamics in normal, mutated, and drug-treated conditions upon multitudes of kinetic stimulations and quantify which proteins and reaction rates are most sensitive to which extracellular stimulations.…”
Publicado 2020
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1773“…Flatfoot is a common deformity in the pediatric population and has a multitude of causes. Sometimes, it can be a normal finding in children, and treatment should not be guided only based on the appearance, but rather after thoroughly assessing the patient and the impact it has on the child’s daily life. …”
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1774“…The amounts and toxicity of reagents, generated waste, energy requirements, the number of procedural steps, miniaturization, and automation are just a few of the multitude of criteria considered when assessing an analytical methodology’s greenness. …”
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1775por Kant, Sam, Menez, Steven P., Hanouneh, Mohamed, Fine, Derek M., Crews, Deidra C., Brennan, Daniel C., Sperati, C. John, Jaar, Bernard G.“…The incidence of AKI in patients with CoVID-19 is variable across numerous international studies, but the high incidence of AKI and its associated worse outcomes in the critical care setting are a consistent finding. A multitude of patterns and mechanisms of AKI have been elucidated, and novel strategies to address shortage of renal replacement therapy equipment have been implemented. …”
Publicado 2020
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1776“…However, in view of the multitude of possible channels that are known to support apoptosis, a model based on specific signaling to a channel presents certain problems. …”
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1777“…This type of multifunctional coating can be beneficial in a multitude of applications like self-cleaning AR coating for solar panels, windows in high-rise buildings, sensors, and aerospace applications as well as just utilizing the excellent water repellent behavior in applications where only superhydrophobicity is required.…”
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1778por Nader, Nancy, Dib, Maya, Hodeify, Rawad, Courjaret, Raphael, Elmi, Asha, Hammad, Ayat S., Dey, Raja, Huang, Xin-Yun, Machaca, Khaled“…Our findings outline the early steps involved in mPR signaling and expand the spectrum of mPR signaling through the multitude of pathways involving APPL1.…”
Publicado 2020
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1779“…Strikingly, there is a remarkable lack of kinetic data, likely due to a multitude of experimental challenges related to the insoluble nature of LPMO substrates, like cellulose and chitin, and to the occurrence of multiple side reactions. …”
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1780por Ravikumar, Maanasa, Smith, Raymond Alexander Alfred, Nurcombe, Victor, Cool, Simon M.“…They are ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and the surrounding microenvironment. …”
Publicado 2020
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