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1801“…They presented incidentally with a multitude of fundic gland polyps, 52 and 147, without a family history of polyposis, and these polyps were not attributable to the chronic use of proton pump inhibitors. …”
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1802“…With advancements in gene editing technologies, our ability to make precise and efficient modifications to the genome is increasing at a remarkable rate, paving the way for scientists and clinicians to uniquely treat a multitude of previously irremediable diseases. CRISPR-Cas9, short for clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9, is a gene editing platform with the ability to alter the nucleotide sequence of the genome in living cells. …”
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1803“…Previous studies have explored a multitude of factors influencing student learning outcomes based on various theories. …”
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1804por Mast, Fred D., Fridy, Peter C., Ketaren, Natalia E., Wang, Junjie, Jacobs, Erica Y., Olivier, Jean Paul, Sanyal, Tanmoy, Molloy, Kelly R., Schmidt, Fabian, Rutkowska, Magda, Weisblum, Yiska, Rich, Lucille M., Vanderwall, Elizabeth R., Dambrauskas, Nicolas, Vigdorovich, Vladimir, Keegan, Sarah, Jiler, Jacob B., Stein, Milana E., Olinares, Paul Dominic B., Hatziioannou, Theodora, Sather, D. Noah, Debley, Jason S., Fenyö, David, Sali, Andrej, Bieniasz, Paul D., Aitchison, John D., Chait, Brian T., Rout, Michael P.“…This repertoire samples the epitope landscape of the Spike ectodomain inside and outside the receptor binding domain, recognizing a multitude of distinct epitopes and revealing multiple neutralization targets of pseudoviruses and authentic SARS-CoV-2, including in primary human airway epithelial cells. …”
Publicado 2021
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1805por Lateef, Fatimah, Stawicki, Stanislaw P., Xin, Lee Man, Krishnan, S. Vimal, Sanjan, A., Sirur, Freston Marc, Balakrishnan, Jayaraj Mymbilly, Goncalves, Rose V., Galwankar, Sagar“…Coronavirus disease 2019 (COVID-19) was an impetus for a multitude of transformations – from the ever-changing clinical practice frameworks, to changes in our execution of education and research. …”
Publicado 2020
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1806“…These pathogens employ a multitude of antibiotic resistance mechanisms, such as the production of antibiotic deactivating enzymes, changes in antibiotic targets, or a reduction of intracellular antibiotic concentration, which render them insusceptible to multiple antibiotics. …”
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1807“…Here, we report more than 150,000 photonic band calculations for thousands of natural crystal templates from which we predict 351 photonic crystal templates – including nearly 300 previously-unreported structures – that can potentially be realized for a multitude of applications and length scales, including several in the visible range via colloidal self-assembly. …”
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1808por Kuai, Le, Luo, Ying, Qu, Keshen, Ru, Yi, Luo, Yue, Ding, Xiaojie, Xing, Meng, Liu, Liu, Sun, Xiaoying, Li, Xin, Li, Bin“…Finally, the sequencing results were verified using a multitude of methods, and the mechanism of action of TDGs against psoriasis was found to be via the upregulation of metabolic signaling pathways such as the Gly-Ser-Thr axis, the downregulation of immune and inflammatory pathways, and the decrease in Rac2 and Arhgdib concentrations. …”
Publicado 2021
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1809“…The adaptive immune system provides a diverse set of molecules that can mount specific responses against a multitude of pathogens. Memory is a key feature of adaptive immunity, which allows organisms to respond more readily upon re-infections. …”
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1810por Tan, Yun, Zhang, Wei, Zhu, Zhaoqin, Qiao, Niu, Ling, Yun, Guo, Mingquan, Yin, Tong, Fang, Hai, Xu, Xiaoguang, Lu, Gang, Zhang, Peipei, Yang, Shuangshuang, Fu, Ziyu, Liang, Dongguo, Xie, Yinyin, Zhang, Ruihong, Jiang, Lu, Yu, Shuting, Lu, Jing, Jiang, Fangying, Chen, Jian, Xiao, Chenlu, Wang, Shengyue, Chen, Shuo, Bian, Xiu-Wu, Lu, Hongzhou, Liu, Feng, Chen, Saijuan“…The pathophysiology of coronavirus disease 19 (COVID-19) involves a multitude of host responses, yet how they unfold during the course of disease progression remains unclear. …”
Publicado 2021
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1811por Breuer, Florian, Brettschneider, Paul, Kleist, Per, Poloczek, Stefan, Pommerenke, Christopher, Dahmen, Janosch“…The power cut lasted more than 24h and all those involved were faced with a multitude of challenges. An operational command post was set up in which medical problems had to be continuously identified and re-evaluated. …”
Publicado 2021
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1812“…Such research resulted in a multitude of questionnaires and tools to capture the way students perform in higher education institutions. …”
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1813por Migdal, Maciej, Ruan, Dan Fu, Forrest, William F., Horowitz, Amir, Hammer, Christian“…Human immunogenetic variation in the form of HLA and KIR types has been shown to be strongly associated with a multitude of immune-related phenotypes. However, association studies involving immunogenetic loci most commonly involve simple analyses of classical HLA allelic diversity, resulting in limitations regarding the interpretability and reproducibility of results. …”
Publicado 2021
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1814por Zolotoff, Cindy, Bertoletti, Laurent, Gozal, David, Mismetti, Valentine, Flandrin, Pascale, Roche, Frédéric, Perek, Nathalie“…Obstructive sleep apnea (OSA) is characterized by repeated episodes of intermittent hypoxia (IH) and is recognized as an independent risk factor for vascular diseases that are mediated by a multitude of mechanistic pathophysiological cascades including procoagulant factors. …”
Publicado 2021
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1815“…Thus, a detailed RNA sequencing analysis using TPC1-deficient fibroblasts uncovered a multitude of changes in the expression levels of surface receptors and their pathway-related signaling proteins. …”
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1816“…This approach makes it possible to systematically achieve size- and composition-controlled intermetallic nanocrystals, opening up a multitude of possibilities for these materials.…”
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1817“…In the past decade, application of transcriptomic analysis to skin biology and dermatology has greatly advanced understanding of homeostatic physiology in the skin, as well as a multitude of dermatologic diseases. Single-cell RNA sequencing offers tremendous promise for identification of novel therapeutic targets in dermatologic diseases, with broad implications of improving therapeutic interventions.…”
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1818“…Microbes interact in a multitude of ways with host plants, can dwell as endophytes within plants causing no apparent disease, and often provide benefits to their host. …”
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1819por Watanabe, Sho, Bhat, Vinayak S., Baumgaertl, Korbinian, Hamdi, Mohammad, Grundler, Dirk“…The findings promise as-desired filters and magnonic waveguides reaching out in a multitude of directions of the aperiodic lattice.…”
Publicado 2021
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1820por Francalancia, Jara, Mavrogiorgou, Paraskevi, Juckel, Georg, Mitrovic, Tina, Kuhle, Jens, Naegelin, Yvonne, Kappos, Ludwig, Calabrese, Pasquale“…Even though multiple sclerosis (MS) is a treatable condition today, it is still accompanied by a multitude of impairments, which in turn may intensify of death anxiety. …”
Publicado 2021
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