Mostrando 2,201 - 2,220 Resultados de 198,103 Para Buscar '"mutation"', tiempo de consulta: 0.77s Limitar resultados
  1. 2201
    “…Distinguishing such “driver” mutations from innocuous “passenger” events is critical for prioritizing the validation of candidate mutations in disease-relevant models. …”
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  2. 2202
    por Keum, Young-Sam, Choi, Bu Young
    Publicado 2015
    “…An example is the identification of arginine missense mutations of isocitrate dehydrogenases-1 and -2 (IDH1/2) in glioma, acute myeloid leukemia (AML), chondrosarcomas, and cholangiocarcinoma. …”
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  3. 2203
    “…Phenylketonuria (PKU) is an autosomal recessive disease which results from mutations in the phenylalanine hydroxylase (PAH) gene. …”
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  4. 2204
    “…PURPOSE: This study was initiated to identify causal mutations responsible for autosomal recessive congenital cataracts in consanguineous familial cases. …”
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  5. 2205
    “…B-Raf proto-oncogene (BRAF) mutations are the most common mutations observed in papillary thyroid cancers (PTCs), followed by RET/PTC rearrangements and RAS mutations, while follicular thyroid cancers are more likely to harbor RAS mutations or PAX8/peroxisome proliferator-activated receptor γ (PPARγ) rearrangements. …”
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    “…Glycosylphosphatidylinositol (GPI)-anchored proteins are ubiquitously expressed in the human body and are important for various functions at the cell surface. Mutations in many GPI biosynthesis genes have been described to date in patients with multi-system disease and together these constitute a subtype of congenital disorders of glycosylation. …”
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  11. 2211
    por Shin, HyeonSeok, Cho, Byung-Kwan
    Publicado 2015
    “…Here, we discuss the current applications of deep mutational scanning and consider experimental design.…”
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  17. 2217
    “…The ongoing threat of influenza infection is partly attributable to the emergence of new mutations in the influenza genome. Among the influenza viral gene products, the hemagglutinin (HA) glycoprotein plays a critical role in influenza pathogenesis, is the target for vaccines and accumulates new mutations that may alter the efficacy of immunization. …”
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  18. 2218
    “…We assume that G evolved under the duplication–mutation with complementarity (DMC) model from a seed graph, G(0), and we also observe the binary forest Γ that represents the duplication history of G. …”
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