Mostrando 761 - 780 Resultados de 198,103 Para Buscar '"mutation"', tiempo de consulta: 0.93s Limitar resultados
  1. 761
  2. 762
    “…Recently, an activating mutation of the SRC Gene has been implicated in about one‐tenth of advanced colon cancers. …”
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  5. 765
    por Knopp, M., Andersson, D. I.
    Publicado 2018
    “…This study extends our understanding of epistasis among resistance mutations and shows that interactions between different resistance mutations are often predictable from the characteristics of the individual mutations.…”
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  6. 766
    “…Mechanisms of mutation upregulated by stress responses have been described in several organisms from bacteria to human. …”
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  7. 767
    “…More recently, recurrent histone mutations have been identified in multiple cancers and have been shown to impede histone methylation. …”
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  8. 768
    por Lyons, Daniel M., Lauring, Adam S.
    Publicado 2018
    “…This evolvability is driven, in part, by the virus’s capacity to generate diversity through mutation and reassortment. Because many new traits require multiple mutations and mutations are frequently combined by reassortment, epistatic interactions between mutations play an important role in influenza virus evolution. …”
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  9. 769
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  11. 771
    por Cotton, Ellena, Ray, David
    Publicado 2018
    “…A young woman carrying germline DICER1 mutation was discovered to have a pituitary microprolactinoma when she became amenorrhoic. …”
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  12. 772
    por Koh, Hyun Yong, Lee, Jeong Ho
    Publicado 2018
    “…During the cortical development, cells in the brain acquire somatic mutations that can be implicated in various neurodevelopmental disorders. …”
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  13. 773
    por Liu, Yang, He, Qianchan, Sun, Wei
    Publicado 2018
    “…Genetic association analysis using somatic mutations is an effective approach to study the functional impact of somatic mutations. …”
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  14. 774
    “…Within this commentary, we first discuss the scope of current methods that rank confidence in the overrepresentation of specific mutated genes in cancer genomes. Then we bring to bear recent advances that draw upon an understanding of the development of cancer as an evolutionary process to estimate the effect size of somatic variants leading to cancer. …”
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  15. 775
    “…Mutations of telomerase reverse transcriptase (TERT) and the α thalassemia/mental retardation syndrome X-linked (ATRX) genes have been the subject of numerous studies on the classification and prognosis of glioma. …”
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  16. 776
    por Kotsopoulos, Joanne
    Publicado 2018
    “…Women who inherit a deleterious BRCA1 or BRCA2 mutation face substantially increased risks of developing breast cancer, which is estimated at 70%. …”
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  17. 777
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  19. 779
    “…Temporal evolution of a clonal bacterial population is modelled taking into account reversible mutation and selection mechanisms. For the mutation model, an efficient algorithm is proposed to verify whether experimental data can be explained by this model. …”
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  20. 780
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