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  1. 4741
    por Kufe, Donald
    Publicado 2023
    “…This dependence on MUC1-C extends to other NE carcinomas, such as SCLC and MCC, and identify MUC1-C as a target for the treatment of these aggressive malignancies with the anti-MUC1 agents now under clinical and preclinical development.…”
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    Online Artículo Texto
    Dependence on MUC1-C in Progression of Neuroendocrine Prostate Cancer
  2. 4742
    “…Partitioning of active gene loci to the nuclear envelope (NE) is a mechanism by which organisms increase the speed of adaptation and metabolic robustness to fluctuating resources in the environment. …”
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    Online Artículo Texto
    Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation
  3. 4743
    “…GRAS-1 localizes close to the nuclear envelope (NE) in early prophase I and interacts with NE and cytoskeleton proteins. …”
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    Online Artículo Texto
    GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans
  4. 4744
    “…RESULTS: Using a number of genotyped animals corresponding to at least EIG98 allowed the identification of QTN with the largest effect sizes when Ne was large. Populations with smaller Ne required more than EIG98. …”
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    Online Artículo Texto
    Dimensionality of genomic information and its impact on genome-wide associations and variant selection for genomic prediction: a simulation study
  5. 4745
    “…Recently, perfluorooctyl bromide-nanoemulsion (PFOB-NE) was applied to effectively image macrophage infiltration in a pig model of myocardial infarction using clinical MRI scanners. …”
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    Online Artículo Texto
    Quantitative assessment of angioplasty-induced vascular inflammation with (19)F cardiovascular magnetic resonance imaging
  6. 4746
    “…The receiver operating characteristic (ROC) curve analysis demonstrated that CRP, PCT, IL-6, IL-10, ESR and NE% exhibited excellent diagnostic efficacy for BSI. …”
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    Online Artículo Texto
    PCT, IL-6, and IL-10 facilitate early diagnosis and pathogen classifications in bloodstream infection
  7. 4747
    “…BACKGROUND: We have recently reported that the dietary supplement Meltdown(® )increases plasma norepinephrine (NE), epinephrine (EPI), glycerol, free fatty acids (FFA), and metabolic rate in men. …”
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    Effect of the dietary supplement Meltdown on catecholamine secretion, markers of lipolysis, and metabolic rate in men and women: a randomized, placebo controlled, cross-over study
  8. 4748
    “…CONCLUSIONS: In vivo allergen and DE co-exposure results in elevated CD4, IL-4, CD138 and NE in the respiratory submucosa of atopic subjects, while eosinophils and mast cells are not changed. …”
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    Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects
  9. 4749
    “…RESULTS: Twenty-eight multiparous Holstein cows were fed CON (NE(L) = 1.24 Mcal/kg DM) during d −50 to d −22 relative to calving. …”
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    Peripartal rumen-protected methionine supplementation to higher energy diets elicits positive effects on blood neutrophil gene networks, performance and liver lipid content in dairy cows
  10. 4750
    “…BACKGROUND: Nebraska (NE) Infection Control Assessment and Promotion Program (ICAP) is a CDC funded project. …”
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    Frequently Identified Gaps in Antimicrobial Stewardship Programs in Long-Term Care Facilities
  11. 4751
    “…In 2011, all sponge species at the S-SE side were enriched in d(13)C compared to the E-NE side. In 2013, SI signatures of sponges did not differ between the two sides and were overall lighter in δ(13)C and δ(15)N than in 2011. …”
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    Online Artículo Texto
    Spatio–temporal variation in stable isotope signatures (δ(13)C and δ(15)N) of sponges on the Saba Bank
  12. 4752
    “…Paragangliomas usually produce exclusively norepinephrine (NE) and are more likely to metastasize than adrenal tumors. …”
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    SAT-188 An Unusual Case Of Intra-adrenal Purely Norepinephrine Secreting Pheochromocytoma
  13. 4753
    “…Yeast inclusion had no appreciable influence on performance-based dietary NE utilization or the ratio of observed/expected dietary NE (P ≥ 0.59). …”
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    Evaluation of an active live yeast (Levucell Saccharomyces cerevisiae, CNCM l-1077) on receiving and backgrounding period growth performance and efficiency of dietary net energy utilization in low health risk beef steers()
  14. 4754
    “…Prostate adenocarcinoma with diffuse NE differentiation (median OS: 18.8 months, 95% CI: 15.3–22.3 months) had poor outcome than those with usual CRPC (P = 0.027), while there was no significant change in the focal NE differentiation (median OS: 22.9 months, 95% CI: 18.1–27.7 months, P = 0.136). …”
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    Online Artículo Texto
    Treatment-Emergent Neuroendocrine Prostate Cancer: A Clinicopathological and Immunohistochemical Analysis of 94 Cases
  15. 4755
    “…In 4/33 patients, no controlled (requiring analgesics) or severe pain was detected, and strikingly, 14/15 metastatic sites studied in these men did not express NE markers, suggesting an inverse relationship between NE differentiation and pain in mPC. …”
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    Online Artículo Texto
    Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine
  16. 4756
    “…Prior to Radium-223 administration, patients received a median RAI cumulative activity of 15 GBq (7.4–35.6), external radiation therapy (n = 9), bone surgery (n = 8), cimentoplasty (n = 5), and cryoablation (n = 2). (18)F-FDG PET/CT showed stable disease (SD) in 4/10 and progressive disease (PD) in 6/10 cases after three administrations and SD in 4/10, PD in 5/10 cases, and 1/10 non-evaluable (NE) case after six administrations. After six injections, (99m)Tc-HMDP bone scan showed SD in 9 cases and was NE in 1 case; (18)FNa PET/CT showed SD in 8 cases, partial response (PR) in 1 case, and was NE in 1 case. …”
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    Online Artículo Texto
    RADTHYR: an open-label, single-arm, prospective multicenter phase II trial of Radium-223 for the treatment of bone metastases from radioactive iodine refractory differentiated thyroid cancer
  17. 4757
    “…RESULTS: In vitro experiments show two-color PFC-NE demonstrated high fluorescent and colloidal stability, and that it was readily incorporated into RAW 264.7 macrophages. …”
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    Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopy
  18. 4758
    “…C3 nephritic factors (C3NeFs) were detected in 20 patients and remained detectable over time despite immunosuppressive treatment. …”
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    Long-term follow-up including extensive complement analysis of a pediatric C3 glomerulopathy cohort
  19. 4759
    “…The correlations between HM-RE and advanced cardiac 3D quantification (3DQA) (r(s) = 0.91-0.95, P < 0.05 for all) were higher than those between HM-NE (r(s) = 0.85-0.93, P < 0.05 for all) and the traditional 2D methods. …”
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    Three-dimensional echocardiographic assessment of left ventricular volume in different heart diseases using a fully automated quantification software
  20. 4760
    “…Median PFSs [95% confidence interval (CI)] were 21.6 (15.6 to 24.9), 13.0 [10.5 to not estimated (NE)], and 15.6 (12.9 to NE) months in cohorts A, B, and C, respectively. …”
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    Efficacy and safety of first-line anlotinib-based combinations for advanced non-small cell lung cancer: a three-armed prospective study
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