“…Achaete-scute homolog 1 (ASCL1) is a neuroendocrine transcription factor specifically expressed in 10-20% of lung adenocarcinomas (AD) with neuroendocrine (NE) differentiation (NED). ASCL1 functions as an upstream regulator of the RET oncogene in AD with high ASCL1 expression (A(+)AD). …”
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“…Coping was inspected for surface irregularities using a stereomicroscope at 10x magnification, and then, they were cemented (Temp Bond NE, Kerr, Romulus, MI) with 5 kg load for 10 min. …”
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“…Among the 20,000 women ne 1,438 women (7.19%) had cytologic abnormalities and 410 (2.05%) women were diagnosed histologically with CIN lesions, including 317 (1.58%) with CIN1, 93 (0.50%) with CIN2/3and 11 (55/100,000) with squamous cell carcinoma (SCC). …”
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“…A number of mechanisms, including ancestral differences in census size, sedentism, exploitation of the natural resources, social stratification or connectivity between groups, might have led to the early differences in Ne detected in our analyses. Irrespective of the specific mechanisms involved, our results provide further evidence that long term cultural differences among populations of Palaeolithic hunter-gatherers are likely to have played an important role in the later Neolithization process.…”
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“…In this study, we sequenced complete mitochondrial genomes from three congeneric Decemunciger (Ampharetidae) individuals that had colonized multiple wood falls in the deep (~1600 m) NE Pacific Ocean. Mitochondrial gene order within Decemunciger was similar to the three other available Terebellomorpha genomes, consistent with the relatively conserved nature of mitochondrial genomes within annelids. …”
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“…On the 28 December 2014, a violent and short paroxysmal eruption occurred at the South East Crater (SEC) of Mount Etna that led to the formation of huge niches on the SW and NE flanks of the SEC edifice from which a volume of ~3 × 10(6) m(3) of lava was erupted. …”
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“…For coronene, the angular distributions of the low energy electrons are quite different from that of simpler targets like Ne or CH(4), which is not the case for fluorene. …”
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“…SUBJECTS AND METHODS: For cross-cultural adaptation, the translation of the original English version of the scale was conducted based on the protocol of the Prevention of Falls Network Europe (ProFaNE). The FES-I (Ar) was administered via face-to-face interviews to 108 community-dwelling elderly Palestinians (61 women and 47 men, aged 60-84 years). …”
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“…The 2.09‐Å resolution structure shows that the imidazole group of His26 is in its singly protonated form in the active site, suggesting that the deprotonated Nɛ2 atom of His26 can attack the anomeric carbon of bound substrate as a nucleophile. …”
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“…Here, we report that PI3K/AKT inhibition alone reduces RE-1 silencing transcription factor (REST) protein expression and induces multiple NE markers in PCa cells. The loss of REST by PI3K/AKT inhibition is through protein degradation mediated by the E3-ubiquitin ligase β-TRCP and REST phosphorylations at the S1024, S1027, and S1030 sites. …”
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“…PACS numbers: 87.53.Bn, 87.53.Kn, 87.55.D‐, 87.55.ne…”
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“…Otherwise, systematic error of about 1%, resulting in underdosage of the target volume, can occur. PACS number: 87.55.ne…”
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“…Prior to dura opening and tumor resection, forty-eight biopsy specimens [23 of contrast-enhancing (CE) and 25 of non-contrast enhancing (NE) regions] from 12 GB patients were obtained by a frameless image-guided stereotactic biopsy technique. …”
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“…This work also showed that it is possible to perform a superficial localized IORT which provides new application possibilities for use of the INTRABEAM system. PACS number: 87.55.ne…”
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“…Attempts must be made in PI practices to lower the imaging dose when feasible. PACS numbers: 87.55ne, 87.55Qr…”
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“…It also resulted in fewer monitor units for most of the prostate cases observed in this study. PACS numbers: 85.55.ne; 87.55.de; 87.55.kd…”
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“…PACS numbers: 87.55.D, 87.55.dk, 87.55.ne…”
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“…Higher rates accompanied by low N:P ratios (1–10.4:1) associated with low temperatures occurred in the surface water where the Pingtan and the Dongshan upwelling regions met (the NE area). In contrast, insignificant rates were observed in the southwest area of the Dongshan upwelling region (the SW area) with sufficient N and deficient P, and therefore high N:P ratios (e.g., >43 at station C2) due largely to the influence of the Pearl River plume. …”
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“…Results: The finalized NE had a droplet size of 58±1 nm. In vitro release of 90.92 ± 0.6% in 8 hr for P60 and 99.39 ± 0.5% in 6 hr for CRB was observed in simulated vaginal fluid. …”
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“…Alvelestat can inhibit neutrophil elastase (NE), which serves an important role in NET formation, so we investigated whether alvelestat could protect against ALI in cell and mouse models. …”
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