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7281por Nakagawa, Seishu, Takeuchi, Hikaru, Taki, Yasuyuki, Nouchi, Rui, Kotozaki, Yuka, Shinada, Takamitsu, Maruyama, Tsukasa, Sekiguchi, Atsushi, Iizuka, Kunio, Yokoyama, Ryoichi, Yamamoto, Yuki, Hanawa, Sugiko, Araki, Tsuyoshi, Makoto Miyauchi, Carlos, Magistro, Daniele, Sakaki, Kohei, Jeong, Hyeonjeong, Sasaki, Yukako, Kawashima, Ryuta“…“What, will these hands ne’er be clean?” William Shakespeare (Shakespeare, 1606) Macbeth.…”
Publicado 2019
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7282por Filippone, Claudia, Castel, Guillaume, Murri, Séverine, Ermonval, Myriam, Korva, Misa, Avšič-Županc, Tatjana, Sironen, Tarja, Vapalahati, Olli, McElhinney, Lorraine M., Ulrich, Rainer G., Groschup, Martin H., Caro, Valérie, Sauvage, Frank, van der Werf, Sylvie, Manuguerra, Jean-Claude, Gessain, Antoine, Marianneau, Philippe, Tordo, Noël“…Hantaviruses are zoonotic agents transmitted from small mammals, mainly rodents, to humans, where they provoke diseases such as Hemorrhagic fever with Renal Syndrome (HFRS) and its mild form, Nephropathia Epidemica (NE), or Hantavirus Cardio-Pulmonary Syndrome (HCPS). …”
Publicado 2019
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7283“…In contrast, C57BL/6J mice and mice deficient in neutrophil elastase (NE(−/−)) survived high-dose C. auris intravenous challenge, even with cyclophosphamide (CY)-induced immunosuppression. …”
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7284“…These experiments sought to examine how dietary-induced binge eating influences the neuronal activity of the locus coeruleus (LC)-norepinephrine (NE) system. Young adult female Sprague Dawley rats (7–8 weeks old) were exposed to a repeated intermittent (twice weekly) cycle of 30-min access to a highly palatable sweetened fat (i.e., vegetable shortening with 10% sucrose) with or without intermittent (24 h) calorie restriction (Restrict Binge or Binge groups, respectively). …”
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7285“…Here we developed a novel computational tool Ampliconic Copy Number Estimator (AmpliCoNE) that utilizes read sequencing depth information to estimate Y ampliconic gene copy number per family. …”
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7286“…In this study, we investigated whether application of murine clonal embryonic neuroectodermal stem cells can prevent the spinal cord secondary damage and induce functional recovery. Stem cells (NE-GFP-4C cell line) were grafted intraspinally or intravenously immediately or one week after thoracic spinal cord contusion injury. …”
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7287“…The present study suggests that diverse germplasm of NE India could be used for the improvement of root and drought tolerance in rice breeding programmes.…”
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7288“…ETHICS AND DISSEMINATION: Approval for the study was given by the Health Research Authority and the North East Newcastle, North Tyneside 2 Regional Ethics Committee (reference 18/NE/0144) and Teesside University (reference 176/17). …”
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7289por Patton, Austin H, Margres, Mark J, Stahlke, Amanda R, Hendricks, Sarah, Lewallen, Kevin, Hamede, Rodrigo K, Ruiz-Aravena, Manuel, Ryder, Oliver, McCallum, Hamish I, Jones, Menna E, Hohenlohe, Paul A, Storfer, Andrew“…We demonstrate that each method is robust to assembly quality, producing similar estimates of Ne when simulated genomes were fragmented into up to 5,000 scaffolds. …”
Publicado 2019
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7290“…To demonstrate it, a simulation software called MONET (Millefeuille-like Organization NEural neTwork simulator) that partitions a network model as described above was developed. …”
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7291por Weinberg, Robert P., Koledova, Vera V., Subramaniam, Avinaash, Schneider, Kirsten, Artamonova, Anastasia, Sambanthamurthi, Ravigadevi, Hayes, K. C., Sinskey, Anthony J., Rha, ChoKyun“…This is the rate-limiting step in the biosynthesis of the catecholamines – dopamine (DA), norepinephrine (NE), and epinephrine (EP). Catecholamines (CA) play a key role as neurotransmitters and hormones. …”
Publicado 2019
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7292por Bocsan, Ioana Corina, Muntean, Ioana Adriana, Ureche, Corina, Pop, Raluca Maria, Neag, Maria Adriana, Sabin, Octavia, Deleanu, Diana, Buzoianu, Anca Dana“…More patients with monosensitization to ragweed pollen were observed in the NE center (27%) compared to the Central one (20.7%). …”
Publicado 2019
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7293por Bartz, Melanie, Arnold, Lee J., Spooner, Nigel A., Demuro, Martina, Campaña, Isidoro, Rixhon, Gilles, Brückner, Helmut, Duval, Mathieu“…Measured radioactivity of quartz grains from the Moulouya catchment (NE Morocco) provides an internal dose rate in the range of 50–70 µGy/a when using an a-value of 0.07. …”
Publicado 2019
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7294por Yasumizu, Yota, Rajabi, Hasan, Jin, Caining, Hata, Tsuyoshi, Pitroda, Sean, Long, Mark D., Hagiwara, Masayuki, Li, Wei, Hu, Qiang, Liu, Song, Yamashita, Nami, Fushimi, Atsushi, Kui, Ling, Samur, Mehmet, Yamamoto, Masaaki, Zhang, Yan, Zhang, Ning, Hong, Deli, Maeda, Takahiro, Kosaka, Takeo, Wong, Kwok K., Oya, Mototsugu, Kufe, Donald“…MUC1-C activates a MYC→BRN2 pathway in association with induction of MYCN, EZH2 and NE differentiation markers (ASCL1, AURKA and SYP) linked to NEPC progression. …”
Publicado 2020
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7295por Gao, Wayne, Sanna, Mattia, Branston, J Robert, Chiou, Hung-Yi, Chen, Yi-Hua, Wu, Allison, Wen, Chi Pang“…JT adopted the most effective pricing strategy by increasing the real price of its two most popular brands (Mevius and Mi-Ne) and, at the same time, doubling the sales of its cheaper and less popular brand Winston by leaving its nominal retail price unaltered. …”
Publicado 2019
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7296por Medina-Sánchez, Javier, McLaren, Sue J., Ortega-Ramírez, José, Valiente-Banuet, Alfonso“…We propose that the ZAPb and SJRb formed sequentially during the Neogene as a result of new E-W, N-S and NE-SW faults. The continuation of the TEHb extension during the Oligocene widened its lowland area and allowed the formation of an extensive lake. …”
Publicado 2020
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7297por Prundeanu, Ionuţ-Mihai, Chelariu, Ciprian, Balaban, Sorin-Ionuț, Iancu, Ovidiu-Gabriel“…The levels and distribution of 9 trace elements in apples from two orchards in north-east (NE) Romania were measured by means of Atomic Absorption Spectroscopy (AAS) on 42 samples of 9 different apple varieties, with average content ranges of 0.909–4.458 mg·kg(−1) Zn, 0.055–0.409 mg·kg(−1) Cu, 0.700–2.476 mg·kg(−1) Fe, 0.328–0.695 mg·kg(−1) Mn, 0.054–0.257 mg·kg(−1) Ni, 0.005–0.101 mg·kg(−1) Cr, 0.027–0.420 mg·kg(−1) Co, 0.413–1.149 mg·kg(−1) Pb, and 0.025–0.127 mg·kg(−1) Cd. …”
Publicado 2020
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7298“…More accurate estimates of DE will improve the accuracy of ME values, which will ultimately lead to more accurate NE values.…”
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7299“…Les modifications apportées garantissent une meilleure ergonomie, visibilité et capacités de communication, mais elles n’ont pas d’homologation d’utilisation et ne peuvent donc être recommandées qu’en l’absence de solution alternative validée. …”
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7300por Markar, Sheraz Rehan, Griffiths, Ewen A, Behrens, Paul, Singh, Pritam, Vohra, Ravi S, Gossage, James, Underwood, Tim, Hanna, George B“…ETHICS AND DISSEMINATION: NHS Health Research Authority (North East—York Research Ethics Committee) approval was gained 8 November 2019 (REC reference 19/NE/0352). Multiple platforms will be used for the dissemination of the research data, including international clinical and patient group presentations and publication of research outputs in a high impact clinical journal.…”
Publicado 2020
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