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7361por Mouri, Atsuto, Kaira, Kyoichi, Yamaguchi, Ou, Hashimoto, Kousuke, Miura, Yu, Shiono, Ayako, Shinomiya, Shun, Imai, Hisao, Kobayashi, Kunihiko, Kagamu, Hiroshi“…Methods: NSCLC patients with complete response (CR)/partial response (PR) or stable disease (SD)/not evaluable (NE) status plus progression-free survival (PFS) of 180 days after PD-1 blockade from December 2015 to December 2018 were retrospectively registered in our study and were divided into two groups: those with and without systemic steroid use for irAEs. …”
Publicado 2021
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7362por Case, Thomas C., Merkel, Alyssa, Ramirez-Solano, Marisol, Liu, Qi, Sterling, Julie A., Jin, Renjie“…Previously, we have reported that long-term ADT increases the neuroendocrine (NE) hormone – Gastrin Releasing Peptide (GRP) and its receptor (GRP-R) expression in PC cells. …”
Publicado 2021
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7363por Calle, Eusebi, Martínez, David, Brugués-i-Pujolràs, Roser, Farreras, Miquel, Saló-Grau, Joan, Pueyo-Ros, Josep, Corominas, Lluís“…The usefulness of the algorithms is illustrated in the case study of Girona (NE Iberian Peninsula, 148,504 inhabitants). The results show that the algorithms are able to automatically propose locations for a given number of stations. …”
Publicado 2021
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7364“…In this review paper, we detailed our experiences interviewing parents and treating their child with NE with urodynamics and medications at the Changhua Christian Hospital in Taiwan.…”
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7365por Nazeam, Jilan A., Ragab, Ghada M., El-Gazar, Amira A., El-Mancy, Shereen S., Jamil, Lina, Fayez, Sahar M.“…Improvement in rat behavior was reported for the first time and NEG8 abated the dermal contents/protein expression of IGF-1, TGF-β/collagen, Wnt/β-catenin, JAK2/STAT-3, NE, 5-HT, and the inflammatory markers; p(Ser536) NF-κBp65, TLR-2, and IL-6. …”
Publicado 2021
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7366por Oppedisano, Francesca, Mollace, Rocco, Tavernese, Annamaria, Gliozzi, Micaela, Musolino, Vincenzo, Macrì, Roberta, Carresi, Cristina, Maiuolo, Jessica, Serra, Maria, Cardamone, Antonio, Volterrani, Maurizio, Mollace, Vincenzo“…Moreover, lower levels of brain natriuretic peptide (BNP) and serum norepinephrine (sNE) are reported and have a positive effect on cardiac hemodynamics. …”
Publicado 2021
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7367por Wang, Yuanyuan, Xu, Yibin, Xu, Shengliang, Yang, Jinyong, Wang, Kaiying, Zhan, Xiuan“…Along with banning antibiotics, necrotic enteritis (NE), especially subclinical enteritis (SNE), poses a significant threat to the chicken industry; however, probiotics are a potentially promising intervention. …”
Publicado 2021
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7368por Wood, Thomas R., Parikh, Pratik, Comstock, Bryan A., Law, Janessa B., Bammler, Theo K., Kuban, Karl C., Mayock, Dennis E., Heagerty, Patrick J., Juul, Sandra“…BACKGROUND: In the Preterm Erythropoietin (Epo) NeUroproTection (PENUT) Trial, potential biomarkers of neurological injury were measured to determine their association with outcomes at two years of age and whether Epo treatment decreased markers of inflammation in extremely preterm (<28 weeks’ gestation) infants. …”
Publicado 2021
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7369por Arzadún, Guadalupe, Tomezzoli, Renata Nela, Fortunatti, Natalia, Cesaretti, Nora Noemi, Febbo, María Belén, Calvagno, Juan Martin“…The K(min) axes are orientated in the NE–SW quadrants, oscillating from horizontal (base of the sequence-western) to vertical (top of the sequence-eastern) positions, showing a change from tectonic to almost sedimentary fabric. …”
Publicado 2021
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7370por Schuller, Anthony P., Wojtynek, Matthias, Mankus, David, Tatli, Meltem, Kronenberg-Tenga, Rafael, Regmi, Saroj G., Dip, Phat V., Lytton-Jean, Abigail K. R., Brignole, Edward J., Dasso, Mary, Weis, Karsten, Medalia, Ohad, Schwartz, Thomas U.“…Nuclear pore complexes (NPCs) create large conduits for cargo transport between the nucleus and cytoplasm across the nuclear envelope (NE)(1–3). These multi-megadalton structures are composed of about thirty different nucleoporins that are distributed in three main substructures (the inner, cytoplasmic and nucleoplasmic rings) around the central transport channel(4–6). …”
Publicado 2021
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7371“…Earthquakes of this size pose a great threat to NE India, Bangladesh and Myanmar, the most densely populated areas of the world.…”
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7372“…Besides compressional, we identified two NE–SW orienting low strain rate (~ 20 nstrain/a) zones; namely, the Ramganga-Baijro and the Nainital-Almora, where large earthquakes can occur. …”
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7373por Salerno, José Alexandre, Torquato, Thayana, Temerozo, Jairo R., Goto-Silva, Livia, Karmirian, Karina, Mendes, Mayara A., Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Souza, Letícia R Q., Ornelas, Isis M., Veríssimo, Carla P., Aragão, Luiz Guilherme H S., Vitória, Gabriela, Pedrosa, Carolina S G., da Silva Gomes Dias, Suelen, Cardoso Soares, Vinicius, Puig-Pijuan, Teresa, Salazar, Vinícius, Dariolli, Rafael, Biagi, Diogo, Furtado, Daniel R., Barreto Chiarini, Luciana, Borges, Helena L., Bozza, Patrícia T., Zaluar P. Guimarães, Marilia, Souza, Thiago M.L., Rehen, Stevens K.“…Although the S1R antagonist NE-100 triggered those protective effects, it compromised cytoskeleton integrity by downregulating the expression of structural-related genes and reducing beating frequency. …”
Publicado 2021
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7374por Lu, Jiayin, Huang, Jiaqiang, Zhao, Shisu, Xu, Wenjiao, Chen, Yaoxing, Li, Yuanyuan, Wang, Zixu, Dong, Yanjun, You, Renrong, Cao, Jing, Dong, Yulan“…Meanwhile, after CRS, the KEAP1/NRF2 pathway was inhibited and attenuated the antioxidative ability to cause OS of the endometrium. The norepinephrine (NE) triggered β(2)-AR to activate the FOXO1/NF-κB pathway, which induced endometrial inflammation. …”
Publicado 2021
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7375“…Results After treatment, the levels of DA, NE, 5-HT in 2 groups were significantly increased, and those in the observation group were significantly higher than those in the control group (P < 0.05). …”
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7376por Putul, Mahanta, Konwar, Ranjumoni, Dutta, Malamoni, Basumatary, Bharati, Rajbongshi, Madhab Chandra, Thakuria, Kahua Das, Sarma, Bitumoni“…RESULTS: The carried-out research showed no eruption (NE) status of M3 with an overall mean (±SD) age at 17.39 (±2.273) years, although a significantly lower age among males with a mean age of 16.92 (±2.138) years (p value < 0.001) was observed. …”
Publicado 2021
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7377por Bhatt, Shvetank, Devadoss, Thangaraj, Manjula, Santhepete Nanjundaiah, Rajangam, Jayaraman“…According to the monoamine hypothesis, serotonin (5-hydroxy tryptamine, 5-HT), dopamine (DA) and norepinephrine (NE) are the major neurotransmitters (NTs) involved in depression. …”
Publicado 2021
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7378por Su, Hongliang, Bai, Junmei, Fan, Yao, Sun, Tingting, Du, Yan, Li, Yanhua, Wei, Zhiwen, Chen, Teng, Guo, Xiangjie, Yun, Keming“…Then we used liquid chromatography-mass spectrometry (LC-MS) to simultaneously determine the contents of various neurotransmitters – dopamine (DA), norepinephrine (NE), 5-hydroxytryptamine (5-HT), 5-hydroxyindole acetic acid (5-HIAA), glutamic acid (Glu) and glutamine (Gln) – in different brain regions of the prefrontal cortex (PFc), nucleus accumbens (NAc), caudate-putamen (CPu) and hippocampus (Hip), which are believed to be relevant to the drug’s reward effect. …”
Publicado 2021
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7379“…The present review will focus on the role of peripheral immune cells and discuss processes involved in neuroinflammation under two frequent perinatal conditions, systemic infection/inflammation associated with encephalopathy of prematurity (EoP) and hypoxia/ischaemia in the context of neonatal encephalopathy (NE) and stroke at term. Different immune cell subsets in perinatal brain injury including their infiltration routes will be reviewed and critical aspects such as sex differences and maturational stage will be discussed. …”
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7380por Zhou, Haiying, Yu, Xiangyu, Alhaskawi, Ahmad, Dong, Yanzhao, Wang, Zewei, Jin, Qianjun, Hu, Xianliang, Liu, Zongyu, Kota, Vishnu Goutham, Abdulla, Mohamed Hasan Abdulla Hasan, Ezzi, Sohaib Hasan Abdullah, Qi, Binjie, Li, Juan, Wang, Bixian, Fang, Jianyong, Lu, Hui“…In this scenario, we propose a deep learning-based classification method, in which ResNeXt is a suitable deep neural network for practical implementation, followed by transfer learning methods to improve classification results. …”
Publicado 2022
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