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  1. 8041
    “…The median overall survival (OS) of patients with PS 2 and those aged ≥ 75 years were 11.6 (95% CI: 1.4–not evaluable [NE]) months and 11.6 (95% CI 7.4–18.1) months, respectively. …”
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    Pembrolizumab monotherapy for untreated PD-L1-Positive non-small cell lung cancer in the elderly or those with poor performance status: A prospective observational study
  2. 8042
    “…Median (95% CI) PFS was 1.7 (1.3–NE) months and 6- and 12-month PFRs (95% CI) were 22.2% (3.4–51.3%) each. …”
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    Evaluation of the efficacy and safety of TAS0313 in adults with recurrent glioblastoma
  3. 8043
    “…In the same context, the population genetics parameters, number of different alleles (Na), number of effective alleles (Ne), Shannon’s index (I), expected heterozygosity (He), and Unbiased Expected Heterozygosity (uHe), were calculated. …”
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    Genetic diversity using biochemical, physiological, karyological and molecular markers of Sesamum indicum L
  4. 8044
    “…Patients with expression of NE genes while retaining AR-target gene expression may indicate the transition to neuroendocrine differentiation, with clinical characteristics consistent with this phenotype. …”
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    A clinical-grade liquid biomarker detects neuroendocrine differentiation in prostate cancer
  5. 8045
    “…No significant changes were observed in Dopamine (DA) or norepinephrine (NE) levels. There were significant sex differences (p<0.0001) and treatment effects (p=0.0003) in the DOPAC/DA turnover ratio with males exposed to BPA, BPS, and BPF having markedly less turnover rates compared to control. …”
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    RF22 | PMON03 Sex-specific Effects of Bisphenol-A and its Analogs on Monoamine Levels in the Paraventricular Nucleus
  6. 8046
    “…As she had associated hypertension, palpitations, and anxiety, the patient was evaluated for pheochromocytoma.Laboratory workup showed elevated plasma levels of free Metanephrines at 130 (<57 pg/mL), free Normetanephrines at 247 (<148 pg/mL), and a free Total level at 377 (<205 pg/mL). 24-hour urine collection was consistent with mild elevation of Metanephrines at 330 (90-315 mcg/24 h), normal levels of Normetanephrines at 469 (122-676 mcg/24 h), and normal levels of Total urine Metanephrines of 799 (224-832 mcg/24 h). 24-hour urine free Catecholamines showed: Epinephrine of 6 (2-24 mcg/24 h), Norepinephrine of 77 (15-100 mcg/24 h), and a Total (Epi+NE) of 83 (26-121 mcg/24 h), with Dopamine of 220 (52-480 mcg/24 h).Due to mildly elevated metanephrine levels, the patient was started on the alpha-blocker doxazosin. …”
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    PMON88 A Rare Case of Composite Paraganglioma in the Bladder
  7. 8047
    “…In half of the sample, story recordings contained artificially enhanced rise times (GG-FL_EE group, n = 31), while in the other half, stories remained unprocessed (GG-FL_NE group, n = 31; Clinical Trial Number S60962—https://www.uzleuven.be/nl/clinical-trial-center). …”
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    Speech perception deficits and the effect of envelope-enhanced story listening combined with phonics intervention in pre-readers at risk for dyslexia
  8. 8048
    “…The effective number of alleles (ne) ranged from 1.35 to 1.58 with a mean of 1.48 per locus. …”
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    Genetic variability analysis of Russian cultivars of ryegrass (Lolium) based on SCoT markers
  9. 8049
    “…The samples were obtained from museum collections in Berlin (DE), Burgdorf (DE), Leiden (NE), Manchester (UK), Munich (DE), St. Gallen (CH), Turin (IT), and Zagreb (HR). …”
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    Metagenomic analysis of Ancient Egyptian canopic jars
  10. 8050
    “…Both cytokine release syndrome and neurologic events (NE) were more frequent in the axi-cel group (88% vs. 73%, P=0.003, and 42% vs. 16%, P<0.001, respectively). …”
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    Axicabtagene ciloleucel compared to tisagenlecleucel for the treatment of aggressive B-cell lymphoma
  11. 8051
    “…CONCLUSIONS: Non-Hispanic Black and Hispanic/Latino children living in Douglas County, NE experience disproportionately higher exposure to criteria pollutant concentrations. …”
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    Role of social determinants of health in differential respiratory exposure and health outcomes among children
  12. 8052
    “…METHODS: We conducted a population-based, multicenter, propensity score-matched cohort study with consecutive adult patients (≥ 18 years) diagnosed with COVID-19 using the TriNeTx research network platform. The outcomes of patients with AIH (main group) were compared to a propensity score-matched cohort of patients: (1) Without chronic liver disease (CLD); and (2) Patients with CLD except AIH (non-AIH CLD) control groups. …”
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    Clinical characteristics and outcomes of COVID-19 in patients with autoimmune hepatitis: A population-based matched cohort study
  13. 8053
    “…Il est pertinent de comparer le pronostic des diabétiques hospitalisés pour Covid-19 et traités par metformine, à ceux qui ne reçoivent pas ce traitement. MATÉRIELS ET MÉTHODES: C’est une étude rétrospective réalisée au service des urgences du CHU Farhat Hached de Sousse. …”
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    Metformine et mortalité par la COVID-19
  14. 8054
    “…The median time to response was 1.4 months (95% CI, 1.3–1.4), the median duration of response was not reached, and the median progression‐free survival was 6.3 months (95% CI, 4.9–not estimable [NE]). Eight (25.8%) of 31 patients had ≥grade 3 treatment‐emergent adverse events. …”
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    Pemigatinib in previously treated Chinese patients with locally advanced or metastatic cholangiocarcinoma carrying FGFR2 fusions or rearrangements: A phase II study
  15. 8055
    “…Le MC fait augmenter la PtcCO2 médiane de manière significative 44 vs 41 (p = 0,004) sans modification significative de l’échelle de dyspnée. On ne note pas d’anomalie de la SpO2. CONCLUSION: Le port du masque chirurgical modifie donc le niveau de PtcCO2 chez les patients atteints du SO. …”
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    Effet du masque chirurgical chez les patients atteints du syndrome d’Ondine
  16. 8056
    “…RÉSULTATS: Pour les deux groupes, les trois échelles forment des clusters et ne semblent pas interagir entre elles. La comparaison des réseaux a révélé que la plupart des différentes connexions se situent dans la symptomatologie insomniaque. …”
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    Santé mentale du personnel hospitalier belge durant la première vague de COVID-19
  17. 8057
    “…AC treatment significantly reduced the levels of monoamine and acetylcholine neurotransmitters in the brains of rats, including acetylcholine (Ach), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), norepinephrine (NE), and serotonin (5-HT). Combined AC and CH treatment regulated the abnormal concentrations and metabolisms of neurotransmitters. …”
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    Protective effect of compatible herbs in Jin-Gu-Lian formula against Alangium chinense-induced neurotoxicity via oxidative stress, neurotransmitter metabolisms, and pharmacokinetics
  18. 8058
    “…Il existe cependant peu de données concernant les patients sous anti-CD20 et l’évaluation isolée de la réponse humorale (sérologie) ne rend compte de l’immunogénicité vaccinale que de façon incomplète. …”
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    Les anti-CD20 : principal facteur prédictif de réponse vaccinale humorale et cellulaire dans une cohorte de patients atteints de diverses affections dysimmunitaires : une étude prospective en vie réelle
  19. 8059
    “…INTRODUCTION: Avant que le rôle bénéfique de la dexaméthasone ne soit établi au cours de l’infection au COVID-19 dans une large étude randomisée anglaise (RECOVERY) en juillet 2020, plusieurs voies thérapeutiques alternatives ont été testées, notamment le tocilizumab (TCZ), un inhibiteur de la voie de signalisation du récepteur de l’interleukine-6. …”
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    Tocilizumab au cours du COVID-19 : le plus tôt serait le mieux ? Une analyse exploratoire de cohorte
  20. 8060
    “…Aucun examen complémentaire ne doit retarder la prise en charge thérapeutique. …”
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    Ischémies aiguës et infection COVID-19
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