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  1. 1981
    “…In this report, we describe the natural history of a conservatively treated patient and include quality-of-life issues such as childbearing, athletic participation, and occupational selection. …”
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  2. 1982
    por Volpe, Alessandro
    Publicado 2007
    “…Based on these considerations and on the available data on the natural history of SRMs, it seems reasonable to consider that we may be overtreating these lesions. …”
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  3. 1983
  4. 1984
    “…BACKGROUND AND AIMS: Mood may have an important role in the natural history of inflammatory bowel disease (IBD). However, the impact of antidepressant use on prognosis is unknown. …”
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  5. 1985
    “…BACKGROUND: Acquired myasthenia gravis (AMG) is increasingly recognized in cats, yet information regarding the natural history of the disease, treatment, and outcome including occurrence of immune and spontaneous remission remains limited. …”
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  6. 1986
    por Collins, Stephen M
    Publicado 2020
    “…The review also acknowledges the need for better-designed clinical studies evaluating the impact of behavioral disorders and their treatments on the natural history of IBD, utilizing hard end points to assess changes in the inflammatory process as opposed to reliance on symptom-based assessments. …”
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  7. 1987
    por Sharma, Sat, Anthonisen, Nicholas
    Publicado 2012
    “…Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are a common occurrence and characterize the natural history of the disease. Over the past decade, new knowledge has substantially enhanced our understanding of the pathogenesis, outcome and natural history of AECOPD. …”
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  8. 1988
    “…In addition to evaluating vaccine efficacy, household studies have been used to learn about transmission and natural history of many infections. Aspects of the natural history studied in households include the transmissibility, the incubation and latent periods, the duration of infectiousness, and the serial interval between cases (Hope-Simpson 1952; Bailey 1957). …”
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  9. 1989
    “…Management has relied on symptomatic care, and supportive and palliative strategies, but the approval of the enzyme replacement therapy cerliponase alfa in the USA and Europe in 2017 brought different treatment opportunities. We describe the natural history of CLN2 disease, its diagnosis and management, and the preclinical and clinical development of cerliponase alfa. …”
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  10. 1990
  11. 1991
    “…In Brazil, the most representative collections are kept by natural history museums, whose primary focus is in invertebrates, vertebrates and vascular plants. …”
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  12. 1992
    “…However, limited quantitative understanding of natural history and disease progression hinders progress and increases the risks associated with rare disease drug development. …”
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  13. 1993
    “…We compared it to the international prospective longitudinal natural history study (NHS) data from 45 patients (containing 11 German patients). …”
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  14. 1994
    “…We herein emphasize lights and shadows of the current classification of lung NENs and provide an alternative outlook on these tumors focused on what we currently know about the biological determinants and the natural history of disease.…”
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  15. 1995
    “…These findings may help further understanding of the natural history of dementia and how such measures could contribute to strengthening future models of dementia.…”
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  16. 1996
    “…Cervical sagittal alignment, predictive factor, diffusion tensor imaging, and the natural history of CSM may become a frontier in this research field. …”
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  17. 1997
    “…Indeed, PPAOS patients generally present a parkinsonian syndrome late into their natural history mostly qualifying for either corticobasal syndrome (CBS) or progressive supranuclear palsy (PSP). …”
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  18. 1998
    por Hassan, Cesare, Antonelli, Giulio
    Publicado 2021
    “…The main barrier for a young researcher in the field of endoscopy is that too much is known about virtually every aspect not only of the natural history, but also of the efficacy and safety of different Gastrointestinal (GI) techniques. …”
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  19. 1999
    “…Determining the median age at causal HPV infection and CIN2+ diagnosis based on the natural history of HPV disease can help elucidate the incidence of HPV infections and the potential benefits of vaccination in mid-adults. …”
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  20. 2000
    “…However, aspects of Hemidactylus mabouia natural history and ecomorphology, often assumed to be linked with this effect on native populations, remain understudied or untested. …”
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