“…BACKGROUND: Tau positron emission tomography (PET) imaging enables longitudinal observation of tau accumulation in Alzheimer's disease (AD). (18)F-MK6240 is a high affinity tracer for the paired helical filaments of tau in AD, widely used in clinical trials, despite sparse longitudinal natural history data. We aimed to evaluate the natural history of tau accumulation, and the impact of disease stage and reference region on the magnitude and effect size of regional change. …”
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“…BACKGROUND: Understanding the natural history of elevated blood pressure (BP) is important to determine the window for primary prevention of hypertension. …”
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“…Therefore, decisions should be shared by the oncologist and the patient, considering the natural history of cancer, the time elapsed since cancer diagnosis, and IBD prognosis.…”
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“…Unpublished manuscript, dated 1802, dealing with methods to be used in collecting and shipping seeds, tubers and bulbs from colonies in Africa and Brazil to the Natural History Complex of Ajuda, in Portugal.…”
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“…This paper will review the epidemiology, pathogenesis, clinical presentation, diagnosis, natural history, and management of unruptured saccular intracranial aneurysms.…”
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“…Modern therapy for rheumatoid arthritis (RA) is based on knowledge of the severity of the natural history of the disease. RA patients are approached with early and aggressive treatment strategies, methotrexate as an anchor drug, biological targeted therapies in those with inadequate response to methotrexate, and “tight control,” aiming for remission and low disease activity according to quantitative monitoring. …”
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“…In addition COPD is not a stable disease but its natural history is punctuated by periods of acute deterioration or exacerbations. …”
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“…We present an echocardiographic evaluation of an elderly man affected with Ebstein's anomaly. In the natural history of this congenital disease only 5% of patients survive beyond the fifth decade. …”
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“…In contrast, metastatic meningeal involvement is increasingly seen as advances in cancer therapy have changed the natural history of malignant disease and prolonged the life span of cancer patients. …”
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“…To better understand the natural history of Hendra virus infection and its tendency to relapse, 2 humans infected with this virus were monitored after acute infection. …”
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“…Due to the scarcity of reports, their natural history, recurrence, and metastatic potential remain poorly defined. …”
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“…Following recent fieldwork in the north of Morocco, we report five new records for the country (Plagiolepis pygmaea Latreille, 1798, Ponera testacea Emery, 1895, Strumigenys tenuipilis Emery, 1915, Temnothorax pardoi Tinaut, 1987, and Tetramorium parvioculum Guillem & Bensusan, 2009) and we present new data on the distribution and natural history of six additional species. This work brings the total number of ants known from Morocco to 233, taking into account two species which were omitted in the list of Cagniant.…”
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“…In addition, this paper further illustrates the male, and provides the first known observations on the natural history of this species, including habitat, cohabitation, and prey capturedata.…”
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“…Improvements are not usually described in the natural history of degenerative dementia. It seems possible to find the normal workings of impaired learning and lost long‐term memories that appeared to be permanently altered after severe neurodegeneration and synaptic loss. …”
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“…The epidemiology, natural history, presentation, histologic and imaging appearances, prognosis and treatment of this malignancy are reviewed.…”
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“…HIV coinfection added diversity and changed the natural history of syphilis as a systemic infection. We present a rare case of subacute hypophysitis and panhypopituitarism due to an early active neurosyphilis in a previously unknown HIV coinfected patient.…”
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“…Although rare, ectopic salivary gland fistula should be considered in the differential diagnosis when treating a fistulous lesion on the neck because its natural history and the level of difficulty of surgery are different from those of the branchial fistula.…”
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