“…The presence of chronic hyponatremia without cognitive dysfunction, eventually culminating in an acute episode of encephalopathy and severe hyponatremia, is a pattern of natural history not previously documented in this condition.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Delay in diagnosis due to focal nature of the lesion also contributes to the poor prognosis as the dismal natural history and immunosuppressive therapy. To date, only a few cases with tumor-like isolated angitis of CNS have been reported with clear and definitive diagnostic workup.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this review, we focused on the genetic component of NAFLD, with special emphasis on the role of genetics in the disease pathogenesis and natural history. Insights into the topic of the genetic susceptibility in lean individuals with NAFLD and the potential use of genetic tests in identifying individuals at risk are also discussed.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The present report reinforces the concept and highlights the impression that the aortic valvoplasty, independent of the progressive bovine pericardium degeneration, may positively change the natural history of the aortic valve insufficiency.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…More studies are needed to better understand the natural history of NAFLD, especially in the pediatric age group.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Trastuzumab has significantly changed the natural history of HER2-positive breast cancer. However, resistance to trastuzumab remains a substantial clinical problem. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The clinical behavior and natural history of desmoid tumors are unpredictable and management is difficult with many issues remaining controversial, mainly regarding early detection, the role, type and timing of surgery and the value of non-operative therapies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Because the medical literature on this condition is limited, our understanding of the natural history and management of OO is still vague. The management guidelines for asymptomatic OO are preliminary. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Literature reviews on the topic are discussed regarding the histological findings, natural history, and outcome of surgically treated MPE. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BRBV has not been detected in nonhuman vertebrates, and its natural history remains largely unknown.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…INTRODUCTION: Giant Meckel’s diverticula are a relatively rare form of Meckel’s, and henceforth their natural history is not clearly defined. They’re currently thought of as an infrequent form of ileal dysgenesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Regardless of the cause, for many patients the natural history of PH involves progressive elevation in pulmonary arterial resistance and pressure, right ventricular dysfunction, and eventually heart failure. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accumulated during the past decade to provide useful information on the risk factors and prognosis of lung involvements in rheumatic diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These patients were more likely to have stricturing CD but endometriosis does not seem to impact the natural history of CD.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the absence of reliable information about transmission mechanisms of emerging infectious diseases, phenomenological models are useful to characterize epidemic growth patterns without the need to explicitly model transmission mechanisms and the natural history of the disease. In this article, our goal is to discuss and illustrate the role of regularization methods for estimating parameters and generating disease forecasts using the generalized Richards model in the context of the 2014–15 Ebola epidemic in West Africa.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Intensive investigation is underway to determine which autoimmune disorders will most benefit and where in the natural history of these diseases to employ this rapidly developing therapy.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As such, insight into the natural history of OI in adults will be increased. Analysing the data of a large group of adults with this rare disorder within a national expert center will allow detailed exploration of the course of OI over time.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Owing to their rarity as well as their relatively indolent natural history, treatment approaches are not yet standardized. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is an extremely rare pathology with unclear pathogenesis, indeterminate natural history with no consensus on the ideal management of the condition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The role of smoking is crucial in the natural history of lung damage progression in severe AATD individuals, even if it also partly explains the heterogeneity in lung disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso