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  1. 2781
    “…Currently, there is a paucity on natural history data, and appropriate clinical and functional outcome measures are needed. …”
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    LAMA2-Related Muscular Dystrophy Across the Life Span: A Cross-sectional Study
  2. 2782
    “…Long term study and follow up is required to determine if intervention alters the natural history of post traumatic arthritis.…”
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    Poster 148: Preoperative Platelet Rich Plasma Injections Decreases Inflammatory and Chondrodegenerative Biomarkers in Patients with Acute Anterior Cruciate Ligament Tears and Reconstruction: A Pilot Study
  3. 2783
    “…The most important risk factor for the development ofCOPD is cigarette smoking, and smoking cessation has been shown to reduce all-cause mortality and to alter the natural history of COPD. Smoking cessation strategies that employ both counseling and medications like buproprion and nicotine replacement are most effective, but relapse rates remain high.It has not been shown that medications like bronchodilators or inhaled steroids change the natural history of COPD, nor do they reduce mortality, but they can affect other important outcomes. …”
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    Contemporary Issues in the Care of Patients With Chronic Obstructive Pulmonary Disease
  4. 2784
    “…The aim of the present study was to evaluate the role of MCP-1 in the natural history of ovarian cancer and to determine its value as differentiation marker and prognostic marker regarding disease free and overall survival. …”
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    Monocyte chemoattractant protein-1 serum levels in ovarian cancer patients
  5. 2785
    “…Articles in English, French or Spanish with relevant information on prevalence, natural history, screening tools, screening strategies and treatment of LTBI during pregnancy were eligible for inclusion. …”
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    Latent Tuberculosis in Pregnancy: A Systematic Review
  6. 2786
    “…The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. …”
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    EVERREST prospective study: a 6-year prospective study to define the clinical and biological characteristics of pregnancies affected by severe early onset fetal growth restriction
  7. 2787
    “…IMPORTANCE: The natural history of ascending aortic aneurysm (AsAA) is currently not well characterized. …”
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    Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm: A Systematic Review and Meta-analysis
  8. 2788
    “…The prevalence of DICER1 mutations, natural history, and extent of phenotypic heterogeneity are unknown. …”
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    SUN-284 DICER1 Mutations in Adolescent Girls: Clinicopathological Findings and Genetic Correlation
  9. 2789
    “…These aneurysms are typically fusiform in nature, and can extend into the cavernous segment of the ICA. The natural history of these aneurysms is not well understood given their rarity. …”
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    Treatment of Bilateral Giant Fusiform Petrocavernous Aneurysms
  10. 2790
    “…To improve the understanding of HPP in children and in order to shorten the diagnostic time span in the future we studied the natural history of the disease in our large cohort of pediatric patients. …”
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    Pediatric hypophosphatasia: lessons learned from a retrospective single-center chart review of 50 children
  11. 2791
    “…OBJECTIVE: High-dose glucocorticoids (GC) remain the primary therapy to induce remission in Juvenile Dermatomyositis (JDM). Studies of the natural history of GC associated weight gain in children are very limited, especially in the JDM population. …”
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    Changes in total body fat and body mass index among children with juvenile dermatomyositis treated with high-dose glucocorticoids
  12. 2792
    “…We used incremental mixture importance sampling to estimate HIV natural history and ART uptake parameters used in the Spectrum software. …”
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    Disease progression and mortality with untreated HIV infection: evidence synthesis of HIV seroconverter cohorts, antiretroviral treatment clinical cohorts and population‐based survey data
  13. 2793
    “…Consequently, this study aimed to investigate the natural history of S. aureus in in vitro biofilm formation in human plasma media using a flow chamber system. …”
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    Quantitative flow chamber system for evaluating in vitro biofilms and the kinetics of S. aureus biofilm formation in human plasma media
  14. 2794
    “…We aim to generate novel target sequence capture data for all genera of flowering plants, exploiting natural history collections such as herbarium specimens, and augment it with mined public data. …”
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    A Comprehensive Phylogenomic Platform for Exploring the Angiosperm Tree of Life
  15. 2795
    “…METHODS: A two-year, multi-center, prospective, descriptive cohort study was conducted to document the natural history course of MPS IIIA. In the context of this study, semi-structured interviews were performed with parents of children at study entry and one year later. …”
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    Understanding disease symptoms and impacts and producing qualitatively-derived severity stages for MPS IIIA: a mixed methods approach
  16. 2796
    “…BACKGROUND: Cow's milk is a food allergen of public health importance both in the United States and globally. Its natural history and epidemiology have been most studied among infants and young children, but the public health burden it places on adults and older pediatric populations remains unclear. …”
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    The US population-level burden of cow's milk allergy
  17. 2797
    “…RESULTS: Of 1077 patients, 250 met the inclusion criteria and had 95 cumulative person-years natural history follow-up. The overall annualized rebleed rate was 7.3% (95% CI, 3.2–14.5). …”
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    Risk of Early Versus Later Rebleeding From Dural Arteriovenous Fistulas With Cortical Venous Drainage
  18. 2798
    “…Data from 3 studies were used: the predrug screening phase of an open-label extension study evaluating tominersen (NCT03342053) and 2 untreated cohorts—the HD Natural History Study (NCT03664804) and the Digital-HD study. …”
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    A Remote Digital Monitoring Platform to Assess Cognitive and Motor Symptoms in Huntington Disease: Cross-sectional Validation Study
  19. 2799
    “…These long-term data strongly support the current practice of femoral osteoplasty in patients with cam FAI morphologies and suggest that this treatment alters the natural history of FAI.…”
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    Paper 44: Does femoral osteoplasty enhance clinical outcomes and survivorship of FAI surgery at long-term follow-up beyond fifteen years?
  20. 2800
    “…The University of Chicago Monogenic Diabetes Registry, established in 2008, offers insight into the diagnosis, treatment, and natural history of individuals known or suspected to have monogenic diabetes. …”
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    Insight on Diagnosis and Treatment From Over a Decade of Research Through the University of Chicago Monogenic Diabetes Registry
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