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  1. 2821
    por Hirschowitz, B. I.
    Publicado 1992
    “…This paper summarizes the abnormal regulation of gastrin and the biology, natural history, diagnosis, and management of ZE syndrome by medical and surgical means.…”
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    Pathobiology and management of hypergastrinemia and the Zollinger-Ellison syndrome.
  2. 2822
    “…Although parathyroid adenoma and carcinoma have disparate natural history, it can be difficult to differentiate between the two entities. …”
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    Intrathyroidal parathyroid carcinoma: a case report with clinical and histological findings
  3. 2823
    “…We developed a mathematical (compartmental) model of the intrinsic dynamics of H. pylori, which represents the natural history of infection and disease progression. …”
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    A dynamic transmission model for predicting trends in Helicobacter pylori and associated diseases in the United States.
  4. 2824
    por Edula, Raja GR, Picco, Michael F
    Publicado 2009
    “…Treatment options for Crohn’s disease have evolved beyond the early goals of induction and remission and are now more focused on preventing complications by altering the natural history of the disease. The advent of biologic therapies has revolutionized the management of Crohn’s disease. …”
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    An evidence-based review of natalizumab therapy in the management of Crohn’s disease
  5. 2825
    “…BACKGROUND: The insecticides dichlorvos, paradichlorobenzene and naphthalene have been commonly used to eradicate pest insects from natural history collections. However, it is not known how these chemicals affect the DNA of the specimens in the collections. …”
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    Dichlorvos exposure impedes extraction and amplification of DNA from insects in museum collections
  6. 2826
    “…Understanding the natural history of osteochondral defects could lead to the development of strategies for preventing progressive joint damage.…”
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    Osteochondral defects in the ankle: why painful?
  7. 2827
    por Tripathy, Debu
    Publicado 2009
    “…The phenotype imparted by expression of the HER2 gene in breast cancer and progress made in modifying the disease's natural history through pharmacologically modulating its function has served as a paradigm for rationally targeted therapy and personalized medicine. …”
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    HER2 status and breast cancer therapy: recent advances
  8. 2828
    “…Understanding the origin and biology of activated fibroblasts will help in the development of an integrated epithelial-stromal sequence to cancer that will ultimately inform cancer pathogenesis, natural history and future therapeutics.…”
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    Stromal Fibroblasts in Digestive Cancer
  9. 2829
    por Lee, In Kyu
    Publicado 2010
    “…However, recent reports have shown that conservative medical treatment of uncomplicated RCD can be recommended and that such treatment is effective due to the benign and self-limited natural history of RCD. Therefore, in this review, we discuss the controversies surrounding RCD management.…”
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    Right Colonic Diverticulitis
  10. 2830
    por Rubegni, P., Mandato, F., Fimiani, M.
    Publicado 2010
    “…It is not clear whether or not treatment alters the natural history of the disease - the disease stabilized with time in most of the patients with or without continuing treatment. …”
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    Frontal Fibrosing Alopecia: Role of Dermoscopy in Differential Diagnosis
  11. 2831
    “…The past decade has seen remarkable improvements in our understanding of the pathology associated with the condition and the development of PAH-specific therapies with the ability to alter the natural history of the disease. This article reviews the evidence for screening and diagnosis of susceptible patient groups and discusses treatment selection and recommendations based on data available from randomized controlled trials. …”
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    Integrated care and optimal management of pulmonary arterial hypertension
  12. 2832
    “…Known as a disease with an inexorable progression to acute leukemia for many years, its natural history has been dramatically improved by the use of tyrosine kinase inhibitors (TKI). …”
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    Chronic myeloid leukemia therapy in the era of tyrosine kinase inhibitors. The first molecular targeted treatment
  13. 2833
    “…We have reviewed the published literature pertaining to the pathology of the human pancreas throughout all stages in the natural history of T1D. This effort uncovered a series of findings that challenge many dogmas ascribed to T1D and revealed data suggesting the marked heterogeneity in terms of its pathology. …”
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    The pancreas in human type 1 diabetes
  14. 2834
    “…Hodgkin's lymphoma (HL) occurs with increasing frequency in human-immunodeficiency-virus-(HIV-) infected individuals. The natural history and behaviour of HIV-HL is different, being more atypical and aggressive. …”
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    Human Immunodeficiency Virus Infection and Hodgkin's Lymphoma in South Africa: An Emerging Problem
  15. 2835
    por Guglin, Maya
    Publicado 2011
    “…Congestion is therefore the driving force of the natural history of heart failure. Congestion is the syndrome shared by heart failure with preserved and reduced systolic function. …”
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    Diuretics as pathogenetic treatment for heart failure
  16. 2836
    por Carver, Terrence W
    Publicado 2009
    “…The pathogenesis of EIA/EIB may be different in those with persistent asthma compared to those with exercise-induced symptoms only. The natural history of EIA is unclear and may be different for elite athletes. …”
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    Exercise-induced asthma: critical analysis of the protective role of montelukast
  17. 2837
    por Cardona, Pere-Joan
    Publicado 2011
    “…This paper reviews the natural history of liquefaction in humans from a pathological and radiological point of view and discusses how the experimental models available can be used to address the topic of liquefaction and cavity formation. …”
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    A Spotlight on Liquefaction: Evidence from Clinical Settings and Experimental Models in Tuberculosis
  18. 2838
    por Al-Ghamdi, Hamdan
    Publicado 2011
    “…Variceal bleeding is a major event in the natural history of end-stage liver disease with a subsequent high mortality rate. …”
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    Carvedilol in the Treatment of Portal Hypertension
  19. 2839
    por Alfonso, Yenisey, Monzote, Lianet
    Publicado 2011
    “…The impact of highly active antiretroviral therapy (HAART) in the natural history of AIDS disease has been allowed to prolong the survival of people with HIV infection, particularly whose with increased HIV viral load. …”
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    HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites
  20. 2840
    “…An international task force of experts was convened by the American Diabetes Association and the American Podiatric Medical Association in January 2011 to summarize available evidence on the pathophysiology, natural history, presentations, and treatment recommendations for this entity.…”
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    The Charcot Foot in Diabetes
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