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  1. 3321
    por Struelens, Marc J., Vineis, Paolo
    Publicado 2021
    “…Within months of virus emergence, the SARS-CoV-2 genomics, replication, evolution and dissemination dynamics as well as natural history, infection risk and prognostic factors and biology of the disease have been gradually deciphered. …”
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    COVID-19 Research: Challenges to Interpret Numbers and Propose Solutions
  2. 3322
    “…A non-systematic literature review revealed that, in the Italian context, topics such as time to achieve RV protection in children, number of preventable cases and administration time window, compatibility/ease of inclusion in the national vaccination calendar, potential overlaps with the peak of natural history of intussusception and adherence to posology could be impacted by the RV vaccine posology. …”
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    Rotavirus vaccine administration patterns in Italy: potential impact on vaccine coverage, compliance and adherence
  3. 3323
    “…However, the impact of these new drugs in changing the natural history of disease is still under debate. Recent evidence seems to suggest that the extent of their efficacy might be, at least partially, dependent on the timing of their introduction and on the subsequent management strategy. …”
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    Novel trends with biologics in inflammatory bowel disease: sequential and combined approaches
  4. 3324
    “…The rarity of this tumor and paucity of pertinent information regarding its biological potential and natural history have resulted in the application of various treatment modalities. …”
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    Cerebellar liponeurocytoma, a rare tumor: Case report and review of the literature
  5. 3325
    “…Together with evidence from natural history studies and animal models, these results support the use of post-immunization antibody titers as the basis for establishing a correlate of protection for COVID-19 vaccines.…”
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    Evidence for antibody as a protective correlate for COVID-19 vaccines
  6. 3326
    “…Finally, we propose future research directions such as variant validation, in vivo modeling, and natural history characterization.…”
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    Update on the Molecular Genetics of Timothy Syndrome
  7. 3327
    “…Isolated dissection of the internal carotid artery (ICA) is rare in young patients and is a cause for strong suspicion of fibromuscular dysplasia (FMD), especially when associated with artery elongation and tortuosity. The natural history of cerebrovascular FMD is unknown and management of symptomatic patients can be challenging. …”
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    Symptomatic internal carotid artery dissection and kinking in a patient with fibromuscular dysplasia
  8. 3328
    “…The prevalence and natural history of arterial aneurysms in abdominal organ transplant recipients remain uncertain. …”
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    Axillary-iliac bypass to protect a transplanted kidney during abdominal aortic aneurysm repair: case report
  9. 3329
    “…INTRODUCTION: Kummell disease (KD) is a rare cause of vertebral fracture due to osteonecrosis. The natural history of the disease is characterized by a previous minor trauma, a subclinical window period, and then a symptomatic period presenting with disabling pain, kyphosis, or neurologic deficit. …”
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    Impending cauda equina syndrome due to Kummell disease; A case report and literature review
  10. 3330
    “…The emergence of Multisystem Inflammatory Syndrome (MIS-C) following SARS-CoV-2 infection in children and adolescents provided a new diagnostic and management challenge as there is limited knowledge about this condition and its natural history. In existing literature on MIS-C, there are currently no data about long-term outcomes. …”
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    New Onset of Hepatic Steatosis Post-Severe Multisystem Inflammatory Syndrome in Children (MIS-C): A Case Report
  11. 3331
    “…SUMMARY: Several therapeutic options are necessary during obesity’s natural history. Therefore, endobariatrics should act in harmony with lifestyle interventions, diet modification, psychological treatment, pharmacotherapy, and bariatric surgery seeking the best outcome in the long term.…”
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    Endoscopic Procedures for Weight Loss
  12. 3332
    “…Several diseases may occur in the natural history of the aorta, requiring replacement of both semilunar cusps and ascending aorta. …”
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    Pathology of the Aorta and Aorta as Homograft
  13. 3333
    por Pongas, Georgios, Cheson, Bruce
    Publicado 2021
    “…Herein, we present the latest advances in the management of FL, discussing the recently approved therapies in the relapsed and refractory (R/R) setting and various new therapeutic modalities that have the potential to change the treatment landscape and natural history of R/R FL.…”
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    Recent Advances in the Management of Patients with Relapsed/Refractory Follicular Lymphoma
  14. 3334
    “…BACKGROUND: : The natural history of the glycometabolic state in transfusion-dependent β-thalassemia (TDT) patients is characterized by a deterioration of glucose tolerance over time. …”
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    Pancreatic changes affecting glucose homeostasis in transfusion dependent β-thalassemia (TDT): a short review
  15. 3335
    “…This case report, therefore, demonstrates that careful assessment of natural history and physician-supervised OFCs are necessary for adequate diagnosis and the successful management of reintroduction in wheat-induced FPIES.…”
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    Wheat Protein-Induced Enterocolitis Syndrome Complicated With Wheezing: An Approach to Diagnosis and Wheat Reintroduction
  16. 3336
    “…HAA accounts for 20% of all visceral aneurysms and, with a poorly understood natural history, is difficult to diagnose clinically, but early detection and treatment of HAA can improve prognosis.…”
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    Common hepatic artery aneurysm detected by 18F-FDG PET/CT Imaging
  17. 3337
    “…Further understanding of the pathogenesis and natural history of USH2A-related disorders is required to develop innovative treatments and design clinical trials based on reliable outcome measures. …”
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    USH2A-retinopathy: From genetics to therapeutics
  18. 3338
    “…This case demonstrates the natural history of the pathology and presents a safe and effective alternative for its management.…”
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    Alternative treatment for patent ductus arteriosus: a therapeutic challenge
  19. 3339
    por Vera, Cristian, Rueda, Zulma Vanessa
    Publicado 2021
    “…Based on the literature, the authors of this review propose a hypothetical natural history of P. jirovecii infection in humans.…”
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    Transmission and Colonization of Pneumocystis jirovecii
  20. 3340
    “…The tribe Plantagineae (Lamiales) is a group of plants with worldwide distribution, notorious for its complicated taxonomy and still unresolved natural history. We describe the result of a broadly sampled phylogenetic study of tribe. …”
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    Molecular and Morphological Data Improve the Classification of Plantagineae (Lamiales)
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