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  1. 3381
    “…These preliminary results warrant further research, to test the natural history of these findings and the need and timing of treatment. …”
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    Subclinical Myocardial Dysfunction in Patients Recovered from COVID-19 Disease: Correlation with Exercise Capacity
  2. 3382
    “…This Delphi panel aimed to understand how outcomes of the pivotal phase III Mexiletine study (MYOMEX) translate to real world practice and investigate health resource use, quality of life and the natural history of NDM to support economic modelling and facilitate patient access. …”
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    Improving the understanding of how patients with non-dystrophic myotonia are selected for myotonia treatment with mexiletine (NaMuscla): outcomes of treatment impact using a European Delphi panel
  3. 3383
    “…Simple, cost-effective methods are needed to study the natural history of asymptomatic submicroscopic parasitaemia. …”
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    Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies
  4. 3384
    “…The placebo–inotersen group demonstrated sustained improvement in neurological disease progression as measured by mNIS + 7, compared with predicted worsening based on projection of the NEURO-TTR placebo data (estimated natural history). The inotersen–inotersen group demonstrated sustained benefit, as measured by mNIS + 7, Norfolk QoL-DN, and SF-36v2, compared with estimated natural history as well as compared with the placebo–inotersen group. …”
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    Long-term efficacy and safety of inotersen for hereditary transthyretin amyloidosis: NEURO-TTR open-label extension 3-year update
  5. 3385
    “…CONCLUSIONS: The analyses of these six variables allowed to highlight important clinical aspects and natural history of PWS useful to inform future actions to be taken by national health care services and health professionals.…”
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    The Italian registry for patients with Prader–Willi syndrome
  6. 3386
    “…METHODS: Visual and auditory evoked potentials were acquired from participants with MECP2 duplication syndrome and FOXG1 syndrome across five sites of the Rett Syndrome and Rett-Related Disorders Natural History Study. A group of age-matched individuals (mean = 7.8 years; range = 1–17) with Rett syndrome, CDKL5 deficiency disorder, and typically-developing participants served as a comparison group. …”
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    Comparison of evoked potentials across four related developmental encephalopathies
  7. 3387
    “…In that scenario, minimally invasive treatment alternatives have been developed in attempts to change the natural history of the disease. Irreversible electroporation, an interventional procedure that minimizes deleterious effects on adjacent tissues, has proven useful for the treatment of tumors traditionally considered unresectable. …”
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    Role of imaging in the applicability of irreversible electroporation for the management of pancreatic adenocarcinoma
  8. 3388
    por Liu, Nanyang, Jiang, Xuefan, Li, Hao
    Publicado 2023
    “…We call for the establishment of a follow-up system for survivors to help researchers better understand the occurrence, natural history, and optimal management of SARS-CoV-2-related AD and prepare for the future.…”
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    The viral hypothesis in Alzheimer’s disease: SARS-CoV-2 on the cusp
  9. 3389
    “…This highlights the importance of integrating cognitive data with species’ natural history to understand the origins of complex cognition.…”
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    The Evolution of Cognitive Control in Lemurs
  10. 3390
    “…Basilar artery (BA) perforator aneurysms are exceedingly rare causes of subarachnoid hemorrhage. Therefore, the natural history and optimal treatment have not been established, and surgical, endovascular, and conservative management have been used. …”
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    Stent-assisted coiling of a ruptured basilar artery perforator aneurysm: A case report
  11. 3391
    “…Hypertrophic cardiomyopathy (HCM) is a genetic disease of the myocardium that is relatively common in the general population, with an autosomal dominant inheritance as a genetic basis. Clinical and natural history pathways can be very different among patients with HCM. …”
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    Old and new therapeutic solutions in the treatment of hypertrophic cardiomyopathy
  12. 3392
    por Cantù, Giulio
    Publicado 2023
    “…In this first part, the histopathology, aetiology, epidemiology, clinical behaviour, natural history, diagnostic work up, and staging will be examined.…”
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    Nasopharyngeal carcinoma. A “different” head and neck tumour. Part A: from histology to staging
  13. 3393
    por Freeman, Hugh J.
    Publicado 2023
    “…RECENT FINDINGS: Although this phenotype of inflammatory colonic disease was initially recognized decades ago, mainly in the elderly, recent evidence from long term natural history studies along with meta-analyses confirms that its clinical course is usually benign and drug-responsive. …”
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    Segmental Colitis Associated with Diverticulosis (SCAD)
  14. 3394
    “…The present case and the current literature review suggest that supportive management may be appropriate to control disease symptoms, although it does not alter the disease’s natural history, progression, and recurrence.…”
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    Chronic Intrathoracic Gastric Volvulus Management: Could Less Be More?
  15. 3395
    “…Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious diseases. …”
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    Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother
  16. 3396
    “…The knowledge about natural history and feeding ecology of this species is virtually lacking. …”
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    New record and dietary ecology of a poorly known frog, Amolopsshihaitaoi Wang, Li, Du, Hou & Yu, 2022 (Amphibia, Anura, Ranidae), from Ha Giang Province, Vietnam
  17. 3397
    “…This patient represents the youngest child reported to have gaucheroma and also the first one presenting with gaucheroma at the diagnosis and not during the follow up, highlighting that GD should be routinely included in the differential diagnosis of children presenting with splenomegaly and hepatomegaly, taking into account that the early start of ERT can change the natural history of the disease-preventing serious complications.…”
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    Pediatric Gaucher Disease Presenting with Massive Splenomegaly and Hepatic Gaucheroma
  18. 3398
    “…Severe tricuspid valve (TV) regurgitation (TR) has been associated with adverse long-term outcomes in several natural history studies, but isolated TV surgery presents high mortality and morbidity rates. …”
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    Advances in Imaging for Tricuspid Transcatheter Edge-to-Edge Repair: Lessons Learned and Future Perspectives
  19. 3399
    “…Catheter ablation for VF has emerged as an effective tool to alter the natural history of this disease among high-risk individuals. …”
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    Trigger and Substrate Mapping and Ablation for Ventricular Fibrillation in the Structurally Normal Heart
  20. 3400
    por Wong, Florence
    Publicado 2023
    “…There is some evidence that regular infusions of albumin may delay the onset of refractoriness and improve survival, especially if given at an early stage in the natural history of ascites and for a long enough duration. …”
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    Innovative approaches to the management of ascites in cirrhosis
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