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  1. 3461
    por Pascoe, Abigail C, Sundar, Santhanam
    Publicado 2012
    “…BACKGROUND: The natural history of non-metastatic castrate refractory prostate cancer is unknown and treatment options are limited. …”
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    Prostate radiation in non-metastatic castrate refractory prostate cancer provides an interesting insight into biology of prostate cancer
  2. 3462
    “…In this study, we highlight three disparate data sources that can provide insights into evolutionary processes associated with invasion success: biological control organisms, horticultural introductions, and natural history collections. All three data sources potentially provide introduction dates, information about source populations, and genetic and morphological samples at different time points along the invasion trajectory that can be used to investigate preadaptation and evolution during the invasion process, including immediately after introduction and before invasive expansion. …”
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    Underutilized resources for studying the evolution of invasive species during their introduction, establishment, and lag phases
  3. 3463
    por Rix, Michael G., Harvey, Mark S.
    Publicado 2012
    “…A key to species and multi-locus molecular phylogeny complement the species-level taxonomy, with maps, habitat photos, natural history information and conservation assessments provided for all species.…”
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    Australian Assassins, Part II: A review of the new assassin spider genus Zephyrarchaea (Araneae, Archaeidae) from southern Australia
  4. 3464
    por Poudel, Resham R.
    Publicado 2012
    “…Information acquisition was done by reviewing the medical literature published since 1987, with particular attention to the natural history, genetic factors, and treatment of LADA.…”
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    Latent autoimmune diabetes of adults: From oral hypoglycemic agents to early insulin
  5. 3465
    “…A low dose of 1000 cfu/animal of B. melitensis resulted in 45% of mice with tissue burdens eight weeks post-challenge. The natural history of brucellosis in mice challenged by higher aerosol doses was examined by serial euthanizing mice over an eight week period. …”
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    The Pathophysiology of Inhalational Brucellosis in Balb/c Mice
  6. 3466
    “…Moreover, the potential usefulness of IFNλ in the treatment and natural history of this disease is also discussed.…”
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    The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C
  7. 3467
    por Taylor, Samuel A., Hannafin, Jo A.
    Publicado 2012
    “…A thorough understanding of the natural history of these injuries and treatment outcomes will enable the appropriate management of patients and their expectations. …”
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    Evaluation and Management of Elbow Tendinopathy
  8. 3468
    “…CONCLUSION: Knowledge about the natural history of extensive Mongolian spots, their inheritance and association with certain metabolic diseases mainly IEM and Mucopolysaccharidosis aids in the diagnosis and in order to improve the patient's prognosis.…”
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    Extensive Mongolian Spots with Autosomal Dominant Inheritance
  9. 3469
    por Distefano, Giuseppe, Sciacca, Pietro
    Publicado 2012
    “…It is well known that the natural history of chronic heart failure (CHF),regardless of age and aetiology,is characterized by progressive cardiac dysfunction refractory to conventional cardiokinetic, diuretic and peripheral vasodilator therapy. …”
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    Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure
  10. 3470
    “…CONCLUSIONS: These observations if corroborated by in vivo data may possibly account for the deleterious effect of long-term therapy with β(2)-bronchodilators and inhaled glucocorticosteroids on the natural history of asthma.…”
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    Dexamethasone and Salbutamol Stimulate Human Lung Fibroblast Proliferation
  11. 3471
    “…A prospective observational data-base of HCV infection will be developed and used for studies on HCV natural history, response to treatment, pharmaco-economics, disease complications, and HCV epidemiology (including phylogenetic analysis). …”
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    Future research and collaboration: the “SINERGIE” project on HCV (South Italian Network for Rational Guidelines and International Epidemiology)
  12. 3472
    “…While our knowledge of its pathophysiology and natural history remains incomplete, an emphasis has been placed on surgical correction. …”
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    Anomalous aortic origin of coronary arteries from the opposite sinus: A critical appraisal of risk
  13. 3473
    “…So the arteriovenous abnormality was an incidental finding by ultrasound. Because of the natural history of the disease, and the potential severe neurocognitive consequences at long-term followup if left untreated, it was decided to embolize the lesion. …”
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    Vein of Galen Aneurysmal Malformations: An Ultrasonographic Incidental Finding—A Case Report
  14. 3474
    “…OBJECTIVE: To evaluate the natural history of gastric emptying in diabetes. RESEARCH DESIGN AND METHODS: Thirteen patients with diabetes (12, type 1; 1, type 2) had measurements of gastric emptying, blood glucose levels, glycated hemoglobin, upper gastrointestinal symptoms, and autonomic nerve function at baseline and after 24.7 ± 1.5 years. …”
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    A 25-Year Longitudinal Evaluation of Gastric Emptying in Diabetes
  15. 3475
    “…The functional profile of FCSQ correlates with the natural history of F. heteroclitus suggesting that the eurytolerant function of FCSQ may be adaptive.…”
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    Functional and Structural Characterization of a Eurytolerant Calsequestrin from the Intertidal Teleost Fundulus heteroclitus
  16. 3476
    “…Histologically, a strong concordance with the natural history of ONFH in humans was found. The present model demonstrated bone trabeculae, marrow necrosis, a reconstruction deficiency and destruction of the microcirculation. …”
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    An animal model of femoral head osteonecrosis induced by a single injection of absolute alcohol: An experimental study
  17. 3477
    “…PH development in mice is of necessity faster and with different physiologic ramifications than found in human disease, and so mice make poor models of natural history of PH. However, transgenic mouse models are a perfect tool for studying the processes involved in pulmonary vascular function and disease, and can effectively be used to test interventions designed against particular molecular pathways and processes involved in disease.…”
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    A process-based review of mouse models of pulmonary hypertension
  18. 3478
    “…Macrophages sense cues (hypoxia, cell death, iron overload) in the lesions and react delivering signals to restore the local homeostasis: their action represents a necessary, non-redundant step in the natural history of the disease. Endometriosis may be due to a misperception of macrophages about ectopic endometrial tissue. …”
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    Endometriosis, a disease of the macrophage
  19. 3479
    “…Tunney at Mount Anderson in the West Kimberley region of northern Western Australia in 1901, now deposited in the Natural History Museum, London. Possible accounts from living memory of Zaglossus are provided by Aboriginal inhabitants from Kununurra in the East Kimberley. …”
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    Twentieth century occurrence of the Long-Beaked Echidna Zaglossus bruijnii in the Kimberley region of Australia
  20. 3480
    por Sha, Sharon J, Boxer, Adam
    Publicado 2012
    “…Ultimately, research consortiums incorporating animal models and well-characterized clinical populations will be necessary to fully understand the natural history of the c9FTD/ALS clinical phenotypes and identify biomarkers and therapeutic agents that can cure the most common form of genetically determined FTD and ALS.…”
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    Treatment implications of C9ORF72
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