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  1. 3501
    “…Therefore, these adjuvants show promise for the treatment of HPV generated lesions and may be useful to elucidate the unknown roles of immune cells in the natural history of HPV infection. This review focuses on HPV immune evasion mechanisms and on the proposed response of the innate immune system, suggesting a role for the surrounding pro-inflammatory microenvironment and the NK and NKT cells in the clearance of HPV infections.…”
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    Role of Innate Immunity against Human Papillomavirus (HPV) Infections and Effect of Adjuvants in Promoting Specific Immune Response
  2. 3502
    “…Little is known about the natural history of the Sphaerodactylus species endemic to the three islands located in the Mona Passage separating the Greater Antillean islands of Hispaniola and Puerto Rico. …”
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    Colonization of islands in the Mona Passage by endemic dwarf geckoes (genus Sphaerodactylus) reconstructed with mitochondrial phylogeny
  3. 3503
    “…Further studies aimed at evaluating the extra-muscle involvement in this group of patients will help to better define clinical features and prognostic factors and to delineate the natural history of the disease.…”
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    Non-muscle involvement in late-onset Glycogenosis II
  4. 3504
    “…Meanwhile, no indications for treatment have been established in APF patients without symptoms, as the natural history of posttraumatic APF is not well understood. …”
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    A Case Report of Spontaneous Closure of a Posttraumatic Arterioportal Fistula
  5. 3505
    “…This review will discuss the epidemiology, natural history, and cardiometabolic risk associated with obesity, provide an overview on current obesity pharmacotherapy, and summarize the recent clinical efficacy and safety data underpinning the FDA’s approval of both phentermine/topiramate ER and lorcaserin as pharmacotherapy for a long-term obesity intervention.…”
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    Management of obesity and cardiometabolic risk – role of phentermine/extended release topiramate
  6. 3506
    “…This patient reported improvements in pain and disability following antioxidant amino acid therapy for a total of 6 months. The natural history of fluoroquinolone toxicity is unknown and may account for the observed improvements.…”
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    Fluoroquinolone toxicity symptoms in a patient presenting with low back pain
  7. 3507
    “…This case report describes the natural history of this type of tumor in a patient who refused adjuvant therapy following surgical resection.…”
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    Pilomyxoid astrocytoma of the cerebellar vermis in an elderly patient
  8. 3508
    por Deere, Jesse D., Barry, Peter A.
    Publicado 2014
    “…The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. …”
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    Using the Nonhuman Primate Model of HCMV to Guide Vaccine Development
  9. 3509
    “…Our concept of the natural history of diabetic kidney disease has to be modified by our results and others. …”
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    Therapeutic management of diabetic kidney disease
  10. 3510
    “…The objective of the paper is to provide detailed characterization of pain developing in the natural history of trigeminal neuralgia and temporomandibular joint dysfunction, with particular focus on similarities accounting for the difficulties in diagnosis and treatment as well as on differences between both types of pain. …”
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    Differential Diagnostics of Pain in the Course of Trigeminal Neuralgia and Temporomandibular Joint Dysfunction
  11. 3511
    por Nathan, Steven D., Meyer, Keith C.
    Publicado 2014
    “…RECENT FINDINGS: Although the results of many IPF clinical trials have been disappointing, these trials have provided valuable insights into the epidemiology and natural history of the disease and have sparked debate into the best clinical trial designs and endpoints. …”
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    IPF clinical trial design and endpoints
  12. 3512
    “…Our study documents the natural history of the impact that vaccination has on Mtb's physiology and replication and highlights the value of reporter Mtb strains for probing heterogeneous Mtb populations in the context of a complex, whole animal model.…”
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    Exploitation of Mycobacterium tuberculosis Reporter Strains to Probe the Impact of Vaccination at Sites of Infection
  13. 3513
    “…Despite considerable advances in prostate cancer early detection and clinical management, validation of new biomarkers able to predict the natural history of tumor progression is still necessary in order to reduce overtreatment and to guide therapeutic decisions. …”
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    MicroRNA as New Tools for Prostate Cancer Risk Assessment and Therapeutic Intervention: Results from Clinical Data Set and Patients' Samples
  14. 3514
    “…Our analysis shows how qualitative ideas in natural history, like the concept of pollination syndromes, can be given more precise definition and rigorous statistical testing that takes into account phylogenetic information.…”
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    The colorful language of Australian flowers
  15. 3515
    “…Few cases have been reported; however, conclusive information about their natural history is not available and the best mode of treatment remains controversial. …”
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    Lumbar Intervertebral Discal Cyst: A Rare Cause of Low Back Pain and Radiculopathy. Case Report and Review of the Current Evidences on Diagnosis and Management
  16. 3516
    por Arredondo, Armando
    Publicado 2014
    “…DISCUSSION: Current health systems are not prepared to respond in a comprehensive manner to all phases of the natural history of the disease. There are new models of universal coverage, but resources and models of care are focused on programs aimed at healing/rehabilitation, and very sparsely at detection/prevention. …”
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    Type 2 diabetes and health care costs in Latin America: exploring the need for greater preventive medicine
  17. 3517
    “…The aim of the present study was to assess the morbidity of ampullary renal pelvis (ARP) and document its natural history in post-natal life. A total of 1,167 newborn infants with prenatally suspected hydronephrosis were retrospectively analyzed. …”
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    Diagnosis of 65 cases of ampullary renal pelvis after postnatal follow-up of 1,167 newborn infants with prenatally suspected hydronephrosis
  18. 3518
    “…INTRODUCTION: Primary hepatic sarcomas are uncommon malignant neoplasms; prognostic features, natural history, and optimal management of these tumors are not well characterized. …”
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    Cardiac metastases and tumor embolization: A rare sequelae of primary undifferentiated liver sarcoma
  19. 3519
    “…These questions include the following: (1) What is the natural history of anterior cruciate ligament (ACL) deficiency? …”
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    Anterior Cruciate Ligament Reconstruction and Osteoarthritis: Evidence from Long-Term Follow-Up and Potential Solutions
  20. 3520
    “…Magnetic resonance enterography to assess disease severity in Crohn's disease may provide an opportunity to study the prevalence and natural history of this rare splenic tumor.…”
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    Littoral Cell Angioma in a Patient with Crohn's Disease
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