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Historia natural
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3941por Senna, G., Guerriero, M., Paggiaro, P. L., Blasi, F., Caminati, M., Heffler, E., Latorre, M., Canonica, G. W.“…After their recruitment, SA patients will be followed in the long term in order to investigate the natural history of the disease. Besides clinical data, the cost/benefit evaluation of the new biologics will be verified as well as the search of peculiar biomarker(s) of the disease.…”
Publicado 2017
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3942“…CONCLUSION: These results suggest that there is uncertainty regarding the optimum age for PPV ligation and adequate underlying variability in practice to support a prospective study of the optimum age for hydrocele repair and the natural history of PPV closure.…”
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3943por Rice, Lauren J., Gray, Kylie M., Howlin, Patricia, Taffe, John, Tonge, Bruce J., Einfeld, Stewart L.“…The development of interventions is greatly aided by understanding gene to behaviour pathways, and this requires an accurate description of the behaviour phenotype, that is, which types and natural history of self-injurious behaviour are more common in PWS and ASD and which are shared with other forms of developmental disability. …”
Publicado 2016
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3944“…It is necessary to elucidate the role of P. jirovecii colonization in the natural history of COPD patients in order to improve the clinical management of this disease. …”
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3945“…Non-motor clinical subtypes, cognitive and non-cognitive, have now been proposed paving the way for possible subtype specific and non-motor treatments, a key unmet need currently. Natural history of these subtypes remains unclear and need to be defined. …”
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3946“…There is a need to design long-term studies to evaluate these interventions in the natural history of the disease. The purpose of this publication is to review our understanding of the role of bacterial infection in patients with COPD exacerbation, the role of antibiotics, and future interventions.…”
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3947“…Little is known about the epidemiology and natural history of multimorbidity; the evidence base is weak; clinical guidelines are not always relevant to this population; and financing and delivery systems have not evolved to adequately measure and reward quality and performance. …”
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3948“…The clinical presentation and the natural history of PBC have improved over the years due to recognition of earlier widespread use of ursodeoxycholic acid (UDCA); about one-third of patients show suboptimal biochemical response to UDCA with poor prognosis. …”
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3949“…Clinical, electrophysiological, and imaging approaches have been used to characterize the natural history of the disease, allowing its classification into four distinct stages, with special emphasis on the prodromal stage, which is characterized by a plethora of motor and non-motor features. …”
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3950“…The advent of the first tailored molecular therapy for SMA, based on modulating the splicing behaviour of the SMN2 gene provides, for the first time, a treatment which alters the natural history of motor neuron degeneration. Here we consider how this will change the landscape for diagnosis, clinical management and future therapeutic trials in SMA, as well as the implications for the molecular therapy of other neurological diseases.…”
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3951por Fattorusso, Valentina, Casale, Alida, Raia, Valeria, Mozzillo, Enza, Franzese, Adriana“…Our case confirms the importance of paying attention to early GMDs in very young CF patients and seems to suggest that earlier therapy could ameliorate CF natural history.…”
Publicado 2017
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3952por Qiu, Zhi-Yuan, Tian, Guang-Yu, Zhang, Zhao, Zhang, Ye-Qing, Xu, Wei, Li, Jian-Yong“…LGL lymphocytosis in transplant recipients may present as a relatively indolent version of the condition and may be more common than reported, but its natural history and clinical course have not been well described, and the lack of a reliable classification system has limited studies on this disease. …”
Publicado 2017
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3953por Frenkel, Amit, Binyamin, Yair, Brotfain, Evgeni, Koyfman, Leonid, Roy-Shapira, Aviel, Shelef, Ilan, Klein, Moti“…This case is presented in order to alert practitioners to the possibility that, after operative fixation of cervical spine injuries, recurrent episodes of bradyarrhythmia can be caused by incorrect placement of the fixation screws and might be confused with the natural history of the high cervical cord injury.…”
Publicado 2017
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3954“…Little is known about the natural history, biology, and population genetic structure of the Hardhead Silverside, Atherinomorus stipes, a small schooling fish found around islands throughout the Caribbean. …”
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3955por Sherwin, LeeAnne B., Ozoji, Onyinyechi M., Boulineaux, Christina M., Joseph, Paule V., Fourie, Nicolaas H., Abey, Sarah K., Zhang, Xuemin, Henderson, Wendy A.“…Participants with IBS (n = 41) and healthy volunteers (n = 74) were recruited into this cross-sectional, descriptive, natural history protocol at the National Institute of Health, Clinical Center. …”
Publicado 2017
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3956por Pombo-de-Oliveira, Maria S, Andrade, Francianne Gomes, Brisson, Gisele Dallapicola, dos Santos Bueno, Filipe Vicente, Cezar, Ingrid Sardou, Noronha, Elda Pereira“…In this review, we have aimed to explore the chain of events in the time-points of the natural history of i-AML, which includes maternal exposures during pregnancy, the speculations about the formation of somatic mutations during foetal life and the secondary genomic aberrations associated with i-AML. …”
Publicado 2017
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3957“…The present study entails descriptions of several well-preserved skulls from the pampathere species Holmesina floridanus, recovered from Pliocene localities in central Florida and housed in the collections of the Florida Museum of Natural History. Bone by bone descriptions have allowed detailed reconstructions of cranial morphology. …”
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3958“…Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is identified by newborn screening (NBS). The natural history of MCADD includes metabolic decompensation with hypoglycemia, hyperammonemia, seizures, coma, and death. …”
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3959por Venuthurupalli, Sree K., Hoy, Wendy E., Healy, Helen G., Cameron, Anne, Fassett, Robert G.“…At present, apart from the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) that reports on CKD patients undergoing renal replacement therapy (RRT), long-term surveillance to describe the natural history of the CKD population not on RRT has only recently started. …”
Publicado 2017
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3960por Alawbathani, Salem, Kawalia, Amit, Karakaya, Mert, Altmüller, Janine, Nürnberg, Peter, Cirak, Sebahattin“…Both were neglected in the past, and the patients presented with a very severe phenotype and unmitigated natural history. PPD is a rare autosomal recessive skeletal dysplasia characterized by progressive joint stiffness, swelling, and pain. …”
Publicado 2018
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