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  1. 4021
    por Zhu, Yifan, Chen, Ying Qing
    Publicado 2020
    “…We introduced a statistical disease transmission model using case symptom onset data to estimate the transmissibility of the early-phase outbreak in China, and provided sensitivity analyses with various assumptions of disease natural history of the COVID-19. We fitted the transmission model to several publicly available sources of the outbreak data until 11, February 2020, and estimated lock down intervention efficacy of Wuhan city. …”
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    On a Statistical Transmission Model in Analysis of the Early Phase of COVID-19 Outbreak
  2. 4022
    por Castro-Rodríguez, J.A.
    Publicado 2007
    “…Viral respiratory infections are the factor most frequently associated with asthma (independently of phenotype, age, and phase of the natural history of asthma during which the infection occurs) and there is a strong temporal association between viral respiratory infections and acute obstructive/asthmatic episodes. …”
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    Relación entre asma e infecciones virales
  3. 4023
    por Wedzicha, J.A.
    Publicado 2002
    “…Increased patient education about detecting and treating exacerbations early in the natural history of COPD can be significantly beneficial. …”
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    Acute Exacerbations of COPD
  4. 4024
    “…BACKGROUND: Mycotic aneurysms are a rare in the pediatric population. The natural history of these lesions and their appropriate management strategies is controversial. …”
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    Malignant clinical course of mycotic intracranial aneurysms in children: A review
  5. 4025
    “…The vast majority of these tumors are sporadic, with the remainder arising as a result of the genetic syndrome Neurofibromatosis Type 2 or, more rarely, LZTR1-related schwannomatosis. The natural history of these tumors is extremely variable, with some tumors not displaying any evidence of growth, others demonstrating early, persistent growth and a small number growing following an extended period of indolence. …”
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    The inflammatory microenvironment in vestibular schwannoma
  6. 4026
    “…In this review, we examine the natural history and risk factors related to DR, emphasizing distinct clinical phenotypes and their natural course in retinopathy. …”
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    Genotypes and Phenotypes: A Search for Influential Genes in Diabetic Retinopathy
  7. 4027
    “…Here, retracing the molecular pathways performed by pluripotent cells at the boundary between neural and non-neural ectoderm in relation to the natural history of NCDT, points of contact or interposition are highlighted to better explain the intricate interplay between cancer cells and the innate and adaptive immune response.…”
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    Innate and Adaptive Immunity Linked to Recognition of Antigens Shared by Neural Crest-Derived Tumors
  8. 4028
    “…This comprehensive overview can illuminate the natural history of similar cases. As the two previously reported cases of encephalitis associated with this virus were not widely discussed regarding the treatment, we share our successful approach and add some recommendations about this new and scarce entity.…”
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    Evolution and resolution of brain involvement associated with SARS- CoV2 infection: A close Clinical – Paraclinical follow up study of a case
  9. 4029
    por Bell, Alyssa, Chiappe, Luis M.
    Publicado 2020
    “…Here, we present a full anatomical description of P. alexi based upon the two nearly complete specimens in the collections of the University of Kansas Natural History Museum, as well as an extensive comparison to other hesperornithiform taxa. …”
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    Anatomy of Parahesperornis: Evolutionary Mosaicism in the Cretaceous Hesperornithiformes (Aves)
  10. 4030
    “…Idiopathic restrictive cardiomyopathy (RCM) is rare, and its natural history is not well known. Its prognosis in infants is extremely poor, whereas patients with RCM occurring in middle age have comparatively good prognoses. …”
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    A case of restrictive cardiomyopathy complicated by recurrent pulmonary thromboembolism originating at the right atrial appendage
  11. 4031
    “…Typhi/Paratyphi A, in a patient group with predisposition, raising the possibility that its natural history is different, and that infection is invasive salmonellosis rather than enteric fever. …”
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    Genetic Markers in S. Paratyphi C Reveal Primary Adaptation to Pigs
  12. 4032
    “…Machine learning (ML) has great potential to drive scientific discovery by harvesting data from images of herbarium specimens—preserved plant material curated in natural history collections—but ML techniques have only recently been applied to this rich resource. …”
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    Machine Learning Using Digitized Herbarium Specimens to Advance Phenological Research
  13. 4033
    “…MPS-IIIA results from a deficiency of heparan sulfatase. The natural history of MPS-IIIA is marked by progressive neurodegeneration. …”
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    The First Reported Case of Hyperreninemic Hypoaldosteronism Due to Mucopolysaccharidosis Disorder
  14. 4034
    “…Although the genetic culprits are not exclusively limited to the intercalated disc, the majority of ACM-linked variants reside within desmosomal genes and are transmitted via Mendelian inheritance patterns; however, penetrance is highly variable. Its natural history features an initial “concealed phase” that results in patients being vulnerable to malignant arrhythmias prior to the onset of structural changes. …”
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    Arrhythmogenic Cardiomyopathy: Molecular Insights for Improved Therapeutic Design
  15. 4035
    “…With technological advances in culture-independent molecular methods, we are uncovering a new facet of our natural history by accounting for the vast diversity of microbial life which colonizes the human body. …”
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    The human gut microbiome in health: establishment and resilience of microbiota over a lifetime
  16. 4036
    “…It has an extremely high morbidity and mortality rate despite immediate treatment and advances in chemo-therapy, radiotherapy, and surgery. In the natural history of the disease, extracranial metastases of glioblastoma multiforme are a rare complication that can be localized in the lungs, bone, liver, and lymph nodes. …”
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    Early Pulmonary Metastasis After a Surgical Resection of Glioblastoma Multiforme. A Case Report
  17. 4037
    “…Nevertheless, many questions and grey areas have to be addressed, such as the natural history of ATTR-AC, the role and implications of genotype–phenotype interactions, the best clinical management, prognostic stratification and the most appropriate treatments, including those already recommended for patients with heart failure. …”
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    Transthyretin amyloid cardiomyopathy: An uncharted territory awaiting discovery
  18. 4038
    “…We measured relative investment in eye size and corneal size for 220 species of anurans representing all 55 currently recognized families and tested whether they were correlated with six natural history traits hypothesized to be associated with the evolution of eye size. …”
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    Eye size and investment in frogs and toads correlate with adult habitat, activity pattern and breeding ecology
  19. 4039
    “…Data concerning SLEs were collected via the Yale OCD Natural History Questionnaire, while for OCD symptoms, the Dimensional Yale–Brown Obsessive–Compulsive Scale was used. …”
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    Stressful Life Events and the Clinical Expression of Obsessive–Compulsive Disorder (OCD): An Exploratory Study
  20. 4040
    por Reimann, Jens, Kornblum, Cornelia
    Publicado 2020
    “…It is especially important to clarify the nature and natural history of brain affection against the background of upcoming specific treatment regimen in hereditary myopathies that should address the brain as a secondary target. …”
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    Towards Central Nervous System Involvement in Adults with Hereditary Myopathies
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