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  1. 4281
    “…Timing and interpretation of imaging methods employed in assessing childhood vascular lesion should also take into consideration the natural history so that imaging is performed to address a specific question. …”
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    Imaging Spectrum of Hemangioma and Vascular Malformations of the Head and Neck in Children and Adolescents
  2. 4282
    “…They always present with secondary complications in adulthood, if the diagnosis and treatment is missed in early years of life. The natural history may be particularly disastrous in cases of bilateral obstructing ureterocele. …”
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    Management of complicated ureteroceles: Different modalities of treatment and long-term outcome
  3. 4283
    “…Some of these models replicate the natural history of symptomatic focal epilepsy with an initial epileptogenic insult, which is followed by an apparent latent period and by a subsequent period of chronic spontaneous seizures. …”
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    Animal models of epilepsy: use and limitations
  4. 4284
    “…Case presentation is followed by a brief discussion of clinical features, natural history and outcome of AA amyloidosis with a particular emphasis on AA amyloidosis as a complication of subcutaneous drug abuse.…”
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    Amyloid A amyloidosis with subcutaneous drug abuse
  5. 4285
    “…SEARCH has also established a longitudinal cohort to assess the natural history and risk factors for acute and chronic diabetes-related complications as well as the quality of care and quality of life of persons with diabetes from diagnosis into young adulthood. …”
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    The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions
  6. 4286
    “…INTRODUCTION: Despite the reduction in mortality incidences of AAA in proportion to increased use of EVAR, the natural history of aneurysms with the presence of an endoleak post EVAR remains unclear. …”
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    Aneurysmal degeneration and type Ib endoleak with proximal aneurysm rupture: A case report, review of literature and technical suggestions
  7. 4287
    “…BACKGROUND: The natural history of patients with symptomatic vertebrobasilar ischemic symptoms due to chronic bilateral vertebral artery occlusive disease is progressive, and poses significant challenges when refractory to medical therapy. …”
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    Intradural vertebral endarterectomy with nonautologous patch angioplasty for refractory vertebrobasilar ischemia: Case report and literature review
  8. 4288
    Publicado 2015
    “…METHODS: Performance of screening strategies (annual/biennial intervals; initiating/terminating ages) was evaluated using a mathematical model based on the natural history of breast cancer and the transition between its stages. …”
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    An Analysis of Mass Screening Strategies Using a Mathematical Model: Comparison of Breast Cancer Screening in Japan and the United States
  9. 4289
    “…To achieve this, we begin by providing an overview of the pathophysiology and natural history of choroidal neovascularization, before reviewing the evidence from both clinical trials and “real-world” outcome studies. …”
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    Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration
  10. 4290
    “…As there is no information about •NO synthesis neither for non-vascular plants nor for non-seed vascular plants, the interesting question regarding the evolution of the enzymatic •NO production systems during land plant natural history remains open. To address this issue the endogenous •NO production by protonema was demonstrated using Electron Paramagnetic Resonance (EPR). …”
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    The Nitric Oxide Production in the Moss Physcomitrella patens Is Mediated by Nitrate Reductase
  11. 4291
    “…At presentation, it may be confused with a gastrointestinal stromal tumor (GIST), but distinguishing between these tumors is critical because the natural history and treatment of these two tumors differs markedly. …”
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    Duodenal gangliocytic paraganglioma: A case report and literature review
  12. 4292
    “…However, for rare cancers this approach is problematic due to the often poor understanding of the disease's natural history and phenotypic heterogeneity, making treatment of these cancers a particularly unmet medical need in clinical oncology. …”
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    Personalized treatment of Sézary syndrome by targeting a novel CTLA4:CD28 fusion
  13. 4293
    por Leleu, H, Blachier, M, Rosa, I
    Publicado 2015
    “…The model simulated the natural history of HCV infection. SVR rates were based on data from clinical trials. …”
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    Cost-effectiveness of sofosbuvir in the treatment of patients with hepatitis C
  14. 4294
    “…This perspective will document the natural history of Texercise Classic, a state-endorsed but previously untested lifestyle health promotion program. …”
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    The Conversion of a Practice-Based Lifestyle Enhancement Program into a Formalized, Testable Program: From Texercise Classic to Texercise Select
  15. 4295
    “…OBJECTIVE: To study the natural history of stone passage in children with ureterolithiasis and to define factors predictive of spontaneous passage. …”
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    Factors that predict the spontaneous passage of ureteric stones in children
  16. 4296
    “…This review outlines the therapeutic potential of DPP-4 inhibitors for the treatment of T2DM, focusing on their main features, clinical applications, and risks, and discusses the major challenges for the future, in particular the possibility of becoming the preferred therapy for T2DM due to their ability to modify the natural history of the disease and ameliorate nephropathy, retinopathy, and cardiovascular complications.…”
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    The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class?
  17. 4297
    “…Using a negative binomial distribution model as a natural history model, the effect of IFNβ-1b was evaluated using different mathematical functions of time. …”
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    A Population Approach to Characterize Interferon Beta-1b Effect on Contrast Enhancing Lesions in Patients With Relapsing Remitting Multiple Sclerosis
  18. 4298
    “…CONCLUSION: The long natural history of this disease highlights the importance of extended follow up for GCT patients. …”
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    A recurrent granulosa cell tumor of the ovary 25 years after the initial diagnosis: A case report
  19. 4299
    “…These data reject the universal applicability of the glacial contraction model to temperate taxa and reiterate the importance of considering the natural history of individual species.…”
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    Thriving in the Cold: Glacial Expansion and Post-Glacial Contraction of a Temperate Terrestrial Salamander (Plethodon serratus)
  20. 4300
    “…Newborn screening programmes for SCD have recently been initiated in Maharashtra, Gujarat, Odisha and Chattisgarh and monitoring these birth cohorts will help to understand the natural history of SCD in India. Prenatal diagnosis is acceptable by tribal families in India. …”
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    Sickle cell disease in tribal populations in India
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