“…Currently, large cohort studies of cognitively healthy participants are undergoing with the main aim of disentangling the natural history of AD to identify individuals with an increased risk of developing AD in the near future to be recruited in these clinical trials. …”
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“…CONCLUSIONS: The distinct natural history, complications, and differences in management reinforce the importance of distinguishing WS from other forms of diabetes. …”
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“…INTRODUCTION: The only etiological and decisive therapy, able to influence the natural history of latex allergy is the specific desensitization. …”
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“…We speculated that as well as incomplete penetrance of the novel mutation and natural history of the disease, an additional pathological condition such as the PFO could contribute to the phenotypical expression in this case of HM.…”
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“…Abstract. Digitization of natural history collections is a major challenge in archiving biodiversity. …”
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“…However, there are several practical problems to be resolved, including the balance of enrollment criteria and cost effectiveness, precise measurements to reduce false positive findings, risk-based optimization of screening frequency, challenges associated with cancer heterogeneity, strategies to combine image screening with novel biomarkers, dynamic monitoring of the natural history of cancer, accurate identification and diagnosis of cases among huge populations, and the impact of tobacco control policy and environment protection. …”
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“…Our model suggests that PRCT have a natural history distinct from that of most common CRCC.…”
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“…Model development was informed by natural history, and preclinical and clinical studies. …”
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“…Thus, the oral route of Trypanosoma cruzi infection, and the consequences in the host must be taken into account when thinking on the mechanisms underlying the natural history of the disease. Distinct routes of parasite entry may differentially affect immune circuits, stimulating regional immune responses that impact on the overall profile of the host protective immunity. …”
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“…Aortic root aneurysms are common problems that can result in aortic dissection or rupture, which is the leading cause of sudden death in the natural history of MFS and LDS, and recent improvements in surgical treatment have improved life expectancy. …”
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“…Development of novel strategies to overcome chemoresistance is central goal in ovarian cancer research. Natural history of the cancer development and progression is being reconstructed by genomic datasets to understand the evolutionary pattern and direction. …”
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“…The aim of our study is to analyze the characteristics, natural history, and postnatal outcome of such cases. …”
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“…The aim of this study was to assess species richness and natural history attributes of the snakes of an assemblage in the Restinga, Tabuleiro and Forest environments of the Atlantic Forest of the south coast of Paraíba, northeastern Brazil. …”
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“…Understanding the natural history of ebolaviruses is a health priority, and investigating these alternative hypotheses could complete the current effort focused on the role of bats.…”
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“…Since two decades the richness and potential of natural history collections (NHC) were rediscovered and emphasized, promoting a revolution in the access on data of species occurrence, and fostering the development of several disciplines. …”
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“…The aim of this paper is to describe the natural history and the clinical signs useful to arise a suspicion of an attenuated form of MPS. …”
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“…Risks of cervical dysplasia progression observed in this study are in agreement with those of the natural history of cervical cancer. Our results suggest that cervical exposure to dilute proflavine does not increase the risk of cervical precancer and cancer.…”
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“…We then simulate an infection transmission process on these networks accounting for the natural history of influenza and calibrated on empirical epidemiological data. …”
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“…What is the limit of animal speed and what mechanisms produce the fastest movements? More than natural history trivia, the answer provides key insight into the form–function relationship of musculoskeletal movement and can determine the outcome of predator–prey interactions. …”
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“…We sought to examine the natural history of fixed pressure. METHODS: We conducted a retrospective chart review of 169 patients undergoing shunt placement by the senior author Daniel Wecht (DW). …”
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