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  1. 8341
    “…Limited population data exist on their prevalence, natural history, or risk of malignant transformation (IPMN-PC). …”
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    Long-Term Outcomes and Risk of Pancreatic Cancer in Intraductal Papillary Mucinous Neoplasms
  2. 8342
    “…METHODS: PVO-1A-001 (NCT02322255) was a prospective, protocol-specified, longitudinal FOP natural history study (NHS). PVO-1A-201 (NCT02190747) was a randomized, double-blind, placebo-controlled phase II trial; PVO-1A-202 (NCT02279095) was its open-label extension. …”
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    Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressiva
  3. 8343
    “…There is limited published data on the nature of these newly defined populations (mPAP 21–24 mmHg and PVR >2–≤3 WU) and the role of comorbidity in determining their natural history. With the change in guidelines, there is a need to understand this population and the impact of the ESC/ERS guidelines in greater detail. …”
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    Predictors of outcomes in mild pulmonary hypertension according to 2022 ESC/ERS Guidelines: the EVIDENCE-PAH UK study
  4. 8344
    por Crozier, W. J., Wolf, Ernst
    Publicado 1944
    “…The evidence thus confirms the suggestion (Menner) drawn from comparative natural history that the visual significance of the avian pecten might be to increase the sensory effect of small moving images. …”
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    THEORY AND MEASUREMENT OF VISUAL MECHANISMS : X. MODIFICATIONS OF THE FLICKER RESPONSE CONTOUR, AND THE SIGNIFICANCE OF THE AVIAN PECTEN
  5. 8345
    “…These findings suggest that respiratory symptoms in the absence of a medical diagnosis of asthma or COPD are by no means trivial, and that clarifying the nature and natural history of respiratory symptoms is a relevant challenge. …”
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    Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey
  6. 8346
    “…BACKGROUND: Men considering the prostate specific antigen (PSA) test for prostate cancer, an increasingly common male cancer, are encouraged to make informed decisions, as the test is limited in its accuracy and the natural history of the condition is poorly understood. …”
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    Supporting Informed Decision Making for Prostate Specific Antigen (PSA) Testing on the Web: An Online Randomized Controlled Trial
  7. 8347
    por Kiatpongsan, Sorapop, Kim, Jane J.
    Publicado 2014
    “…METHODS AND FINDINGS: The analysis was performed using a natural history disease simulation model of HPV and cervical cancer. …”
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    Costs and Cost-Effectiveness of 9-Valent Human Papillomavirus (HPV) Vaccination in Two East African Countries
  8. 8348
    “…Conservative treatment of these injuries has a poor natural history due to recurrent instability with meniscal and articular cartilage damage. …”
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    Return to Play and Clinical Outcomes after All-Inside, Anterior Cruciate Ligament Reconstruction in Skeletally Immature Athletes
  9. 8349
    “…A detailed evaluation was performed for overlap features, the extent and natural history of the DM rash, adermatopathic DM, DM-specific and overlap autoantibodies by protein A immunoprecipitation on coded serum samples, and associations with cancer and survival. …”
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    Redefining Dermatomyositis: A Description of New Diagnostic Criteria That Differentiate Pure Dermatomyositis From Overlap Myositis With Dermatomyositis Features
  10. 8350
    “…Conservative treatment of these injuries has a poor natural history due to recurrent instability with meniscal and articular cartilage damage. …”
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    All-inside, All-epiphyseal ACL Reconstruction in Skeletally Immature Athletes: Incidence of Second Surgery and Two-year Clinical Outcomes
  11. 8351
    “…Overcoming this barrier will be needed to generate meaningful sample sizes to conduct studies of biomarkers, natural history, and clinical effectiveness using linked data.…”
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    Achieving Synergy: Linking an Internet-Based Inflammatory Bowel Disease Cohort to a Community-Based Inception Cohort and Multicentered Cohort in Inflammatory Bowel Disease
  12. 8352
    “…METHODS: We used a dynamic model of HPV transmission, vaccination, natural history and cervical screening to determine the optimal management of women positive for OHR HPV. …”
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    Optimal Management Strategies for Primary HPV Testing for Cervical Screening: Cost-Effectiveness Evaluation for the National Cervical Screening Program in Australia
  13. 8353
    “…OBJECTIVE: The aims of the Stroke Avoidance for Children in REpública Dominicana (SACRED) trial are (1) to screen children with SCA for stroke risk using TCD and to determine the prevalence of elevated velocities in a cross-sectional sample; (2) to identify clinical and laboratory correlates of elevated velocities; and (3) to obtain longitudinal data on the natural history of TCD velocities and to measure therapeutic effects of hydroxyurea. …”
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    Stroke Avoidance for Children in REpública Dominicana (SACRED): Protocol for a Prospective Study of Stroke Risk and Hydroxyurea Treatment in Sickle Cell Anemia
  14. 8354
    “…We investigated the natural history of neuroendocrine changes in relation to P.T.S.D. development in children and adolescents experiencing a motor vehicle accident. …”
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    Neuroendocrine responses to early life stress and trauma and susceptibility to disease
  15. 8355
    “…Due to a significant focus on surgical intervention, there has been limited investigation on the predictive factors and natural history of non-surgical management of these injuries. …”
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    Predictors of Outcomes of Non-Surgical Management for Acetabular Labral Tears
  16. 8356
    “…The feasibility of scaling-up these methods facilitates studying similar populations in different Health Systems, advancing point-of-care studies of natural history and comparative effectiveness research to identify service gaps, evaluate effective interventions, and enhance clinical and data quality improvement.…”
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    2229 A community-academic translational research and learning collaborative to evaluate the associations among biological, social, and nutritional status for adolescent women and their babies using electronic health records (EHR) data
  17. 8357
    por Patick, Amy K.
    Publicado 2006
    “…HRV represent the single most important etiological agents of the common cold [Arruda, E., Pitkaranta, A., Witek Jr., T.J., Doyle, C.A., Hayden, F.G., 1997. Frequency and natural history of rhinovirus infections in adults during autumn. …”
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    Rhinovirus chemotherapy
  18. 8358
    “…We believe that these findings will contribute to a better understanding of the natural history of the disease and will contribute to advances in the implementation of more efficient infection control strategies. …”
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    Clinical and virological data of the first cases of COVID-19 in Europe: a case series
  19. 8359
    “…OBJECTIVE: To describe acute kidney injury (AKI) natural history and to identify predictors of major adverse kidney events (MAKE) within 1 year in patients supported by veno-arterial extracorporeal membrane oxygenation (VA-ECMO). …”
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    Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation
  20. 8360
    “…Genotype-phenotype characterization is important not only for understanding the natural history and clinical manifestation of the disease but also for establishing more accurate and precise diagnostic criteria or therapeutic approaches. …”
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    SAT-622 Heterogeneity of Familial Partial Lipodystrophy Type 2 from a Genotype-Phenotype Perspective
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