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  1. 1281
    “…OBJECTIVE: Asthma is a common chronic disease that imposes a substantial burden on individuals and society. However, the natural history of childhood asthma in a large population remained to be studied. …”
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    Natural history and associated early life factors of childhood asthma: a population registry-based cohort study in Denmark
  2. 1282
    “…Although retrospective, the results provide valuable insight to the natural history of patients undergoing this procedure. …”
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    Natural History of 321 Flatfoot Reconstruction Patients Over a 14 Year Period Performed at a Single Institution
  3. 1283
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    Natural History and Risk Stratification of Recurrent Crohn’s Disease After Ileocolonic Resection: A Multicenter Retrospective Cohort Study
  4. 1284
    “…BACKGROUND: Numerous mathematical models and retrospective analyses have been conducted to explore the natural progression of breast cancer, but there is no precise timeline as to how long it takes breast cancer to progress from stages 0 to IV. Studying the natural history of breast cancer requires the follow-up of a large cohort of patients who received no treatment following diagnosis for a long period, but this has become unpractical in the modern era. …”
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    The natural history of breast cancer: a chronological analysis of breast cancer progression using data from the SEER database
  5. 1285
    “…One crucial reason is that biomarkers for distinguishing the natural history of chronic HBV infection are unmet needs. …”
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    Proteomic characterization of the natural history of chronic HBV infection revealed by tandem mass tag-based quantitative proteomics approach
  6. 1286
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    Retrospective Natural History Study of RPGR-Related Cone- and Cone-Rod Dystrophies While Expanding the Mutation Spectrum of the Disease
  7. 1287
    “…We sought to clarify the natural history of this disorder and its relationship with rheumatologic diseases, such as systemic sclerosis (scleroderma). (2) Methods: We retrospectively identified patients with AC based on high-resolution manometry findings at three referral institutions and then matched them with controls with esophageal complaints who had normal manometries. (3) Results: Seventy-four patients with AC were included (mean age 56 years; 69% female). …”
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    The Natural History of Esophageal “Absent Contractility” and Its Relationship with Rheumatologic Diseases: A Multi-Center Case–Control Study
  8. 1288
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    Paper 88: The Natural History of Anterior Shoulder Instability in Patients Over the Age of 50: A Population Based Study
  9. 1289
    “…This is a retrospective study of TSC Alliance’s Natural History Database aimed to characterize facial angiofibroma and to evaluate features associated with a higher risk of facial angiofibroma or the use of topical mTOR inhibitors for the management of facial angiofibroma. …”
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    Characterization and management of facial angiofibroma related to tuberous sclerosis complex in the United States: retrospective analysis of the natural history database
  10. 1290
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    Retinitis Punctata Albescens and RLBP1-Allied Phenotypes: Phenotype–Genotype Correlation and Natural History in the Aim of Gene Therapy
  11. 1291
    “…This study assessed the natural history of aforementioned patients. METHODS: We retrospectively reviewed the data of 250 patients with HBV-associated decompensated cirrhosis(HBV DNA < 2000 IU/mL) who had not been treated with antiviral medication. …”
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    Natural history of decompensated cirrhosis with serum hepatitis B DNA < 2000 IU/mL: a retrospective study
  12. 1292
    “…OBJECTIVE: We conducted a 5-year observational follow-up natural history study to identify evaluation parameters, which may be useful for the long-term observation of GNE myopathy patients. …”
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    Long-term evaluation parameters in GNE myopathy: a 5-year observational follow-up natural history study
  13. 1293
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    Victorian evolution of inherited retinal diseases natural history registry (VENTURE study): Rationale, methodology and initial participant characteristics
  14. 1294
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    Comprehensive profile and natural history of pediatric patients with spinal muscular atrophy: A large retrospective study from China
  15. 1295
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    EXPLORE B: A prospective, long‐term natural history study of patients with acute hepatic porphyria with chronic symptoms
  16. 1296
    “…Because little is known about the long‐term natural history of subclinical HALT, we aimed to investigate this in patients who underwent TAVR without using additional anticoagulation. …”
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    Natural History of Leaflet Thrombosis After Transcatheter Aortic Valve Replacement: A 5‐Year Follow‐Up Study
  17. 1297
    por Vandriel, Shannon M., Li, Li‐Ting, She, Huiyu, Wang, Jian‐She, Gilbert, Melissa A., Jankowska, Irena, Czubkowski, Piotr, Gliwicz‐Miedzińska, Dorota, Gonzales, Emmanuel M., Jacquemin, Emmanuel, Bouligand, Jérôme, Spinner, Nancy B., Loomes, Kathleen M., Piccoli, David A., D'Antiga, Lorenzo, Nicastro, Emanuele, Sokal, Étienne, Demaret, Tanguy, Ebel, Noelle H., Feinstein, Jeffrey A., Fawaz, Rima, Nastasio, Silvia, Lacaille, Florence, Debray, Dominique, Arnell, Henrik, Fischler, Björn, Siew, Susan, Stormon, Michael, Karpen, Saul J., Romero, Rene, Kim, Kyung Mo, Baek, Woo Yim, Hardikar, Winita, Shankar, Sahana, Roberts, Amin J., Evans, Helen M., Jensen, M. Kyle, Kavan, Marianne, Sundaram, Shikha S., Chaidez, Alexander, Karthikeyan, Palaniswamy, Sanchez, Maria Camila, Cavalieri, Maria Lorena, Verkade, Henkjan J., Lee, Way Seah, Squires, James E., Hajinicolaou, Christina, Lertudomphonwanit, Chatmanee, Fischer, Ryan T., Larson‐Nath, Catherine, Mozer‐Glassberg, Yael, Arikan, Cigdem, Lin, Henry C., Bernabeu, Jesus Quintero, Alam, Seema, Kelly, Deirdre A., Carvalho, Elisa, Ferreira, Cristina Targa, Indolfi, Giuseppe, Quiros‐Tejeira, Ruben E., Bulut, Pinar, Calvo, Pier Luigi, Önal, Zerrin, Valentino, Pamela L., Desai, Dev M., Eshun, John, Rogalidou, Maria, Dezsőfi, Antal, Wiecek, Sabina, Nebbia, Gabriella, Pinto, Raquel Borges, Wolters, Victorien M., Tamara, María Legarda, Zizzo, Andréanne N., Garcia, Jennifer, Schwarz, Kathleen, Beretta, Marisa, Sandahl, Thomas Damgaard, Jimenez‐Rivera, Carolina, Kerkar, Nanda, Brecelj, Jernej, Mujawar, Quais, Rock, Nathalie, Busoms, Cristina Molera, Karnsakul, Wikrom, Lurz, Eberhard, Santos‐Silva, Ermelinda, Blondet, Niviann, Bujanda, Luis, Shah, Uzma, Thompson, Richard J., Hansen, Bettina E., Kamath, Binita M.
    Publicado 2023
    “…This study aimed to elucidate the natural history of liver disease in a contemporary, international cohort of children with ALGS. …”
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    Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study
  18. 1298
    “…In this manuscript, we present a preliminary report on the use of virtual palaeontology methodologies in two natural history museums in central Italy, the Geology and Paleontology Museum of Florence and the Civic Museum of Natural Sciences of Faenza. …”
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    Nurturing Italian Geo-palaeontological Heritage with Virtual Palaeontology: Preliminary Report of Its Application in Two Natural History Museums
  19. 1299
    “…BACKGROUND: Since 1983, the Orphan Product Grants Program, administered by the US Food and Drug Administration, provides funding for clinical trials and natural history studies in rare diseases. The COVID-19 pandemic created new challenges in rare disease product development. …”
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    The effect of the COVID-19 pandemic on US Food and Drug Administration-funded clinical trials and natural history studies for rare diseases
  20. 1300
    “…The catalog is increased by 2281 type specimens (from 454 species or subspecies) to a total of 4180 type specimens (from 770 species or subspecies) hosted at the Pontificia Universidad Católica del Ecuador and Escuela Politécnica Nacional natural history collections. The new material adds 307 holotypes, 1910 paratypes, and 64 allotypes. …”
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    Catalog of the invertebrate type specimens hosted at the Pontificia Universidad Católica del Ecuador and Escuela Politécnica Nacional natural history collections
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