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1981por Zhou, Lan-Ting, Zhang, Juan, Tan, Lu, Huang, He-Zhou, Zhou, Yang, Liu, Zhi-Qiang, Lu, Youming, Zhu, Ling-Qiang, Yao, Chengye, Liu, Dan“…Cholinergic degeneration is one of the key pathological hallmarks of Alzheimer’s disease (AD), a condition that is characterized by synaptic disorders and memory impairments. Nerve growth factor (NGF) is secreted in brain regions that receive projections from the basal forebrain cholinergic neurons. …”
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1982por Magadmi, Rania M., Alsulaimani, Mujahid A., Al-Rafiah, Aziza R., Ahmad, Muhammad Saeed, Esmat, Ahmed“…Briefly, STZ administration caused cold allodynia, induced oxidative stress, and increased nerve growth factor (NGF) concentration. Nevertheless, carvedilol improved the behavioural tests, ameliorated the oxidative imbalance as manifested by reducing malondialdehyde, restoring glutathione content, and superoxide dismutase activity. …”
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1983por Wang, Wenyan, Miao, Yongzhen, Sui, Shangru, Wang, Yanan, Wu, Shen, Cao, Qilong, Duan, Haoyun, Qi, Xia, Zhou, Qingjun, Pan, Xiaojing, Zhang, Jingxue, Chen, Xuehong, Han, Yantao, Wang, Ningli, Kuehn, Markus H., Zhu, Wei“…Exposure to the recombinant cytokines that bind to these receptors, including transforming growth factor beta 1, nerve growth factor beta, erythropoietin, prostaglandin F2 alpha, and epidermal growth factor, can efficiently differentiate iPSCs into TM-like cells, which express TM biomarkers and can form dexamethasone-inducible CLANs. …”
Publicado 2021
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1984por Kasheh Farahani, Zahra, Taherianfard, Mahnaz, Naderi, Mohammad Mehdi, Ferrero, Hortensia“…The assessments of Brain-Derived Neurotrophic Factor (BDNF), Nerve Growth Factor (NGF), Calcitonin Gene-Related Peptide (CGRP), and Substance P levels were carried out by enzyme-linked immunosorbent assay (Elisa). …”
Publicado 2020
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1985“…MSCs exert an immunomodulation effect due to the secretion of endogenous factors, such as vascular endothelial growth factor (VEGF), insulin growth factor (IGF), and nerve growth factor (NGF), transforming growth factor (TGF)-β and growth differentiation factor (GDF)-11. …”
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1986por Li, Yue, Yuan, Yi, Li, Yitong, Han, Dengyang, Liu, Taotao, Yang, Ning, Mi, Xinning, Hong, Jingshu, Liu, Kaixi, Song, Yanan, He, Jindan, Zhou, Yang, Han, Yongzheng, Shi, Chengmei, Yu, Shun, Zou, Peng, Guo, Xiangyang, Li, Zhengqian“…We also observed excessive mitochondrial α-syn accumulation and increased mitochondria-mediated apoptosis in vitro using nerve growth factor-differentiated PC12 cells and primary hippocampal neurons exposed to lipopolysaccharide. …”
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1987por Shang, Zhenying, Li, Chenxi, Liu, Xuemei, Xu, Manhong, Zhang, Xiaomin, Li, Xiaorong, Barnstable, Colin J., Zhao, Shaozhen, Tombran-Tink, Joyce“…Deletion of one or both PEDF alleles resulted in decreased expression of essential trophic support in the TG, LG, and MG including nerve growth factor, brain-derived neurotrophic growth factor, and GDNF with significantly increased levels of NT-3 in the LG and decreased EGF expression in the cornea. …”
Publicado 2021
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1988“…The mRNA expression levels of olfactory receptors (Olfr1494, Olfr1324, Olfr1241, and Olfr979) and neurotrophic factors [brain-derived neurotrophic factor (BDNF), glial cell-derived neurotrophic factor (GDNF), and nerve growth factor (NGF)] were downregulated in the olfactory bulb of the SCI group mice at 8 h post-SCI. …”
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1989“…Colon tissues were collected to study colonic acetylcholine (ACh), the enteric neurons (ChAT, nNOS, and PGP9.5), mast cells activity [Tryptase, prostaglandins E2 (PGE2), and cyclooxygenases-2 (COX2)] and pain markers [nerve growth factor (NGF) and Sub-P]. Key Results: Sacral nerve stimulation significantly improved visceromotor reflexes assessed by the EMG and AWR, compared with sham-SNS. …”
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1990por GHOLIPOUR, Mahin, MIKAELI, Javad, MOWLA, Seyed Javad, BAKHTIARIZADEH, Mohammad Reza, SAGHAEIAN JAZI, Marie, JAVID, Naeme, FAZLOLLAHI, Narges, KHOSHNIA, Masoud, BEHNAMPOUR, Naser, MORADI, Abdolvahab“…The predicted targets for the dysregulated miRNAs showed significant disease-associated pathways like neuronal cell apoptosis, neuromuscular balance, nerve growth factor signaling, and immune response regulation. …”
Publicado 2021
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1991por Sakakibara, Yasufumi, Hirota, Yu, Ibaraki, Kyoko, Takei, Kimi, Chikamatsu, Sachie, Tsubokawa, Yoko, Saito, Takashi, Saido, Takaomi C., Sekiya, Michiko, Iijima, Koichi M.“…However, none of the factors known to be related to the maintenance of LC neurons (i.e., somatostatin/somatostatin receptor 2, brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3) were significantly reduced in App(NL-G-F/NL-G-F) mice. …”
Publicado 2021
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1992por Liu, Wei, Luo, Yiqian, Ning, Cong, Zhang, Wenjing, Zhang, Qingzheng, Zou, Haifeng, Fu, Changfeng“…In this study we investigated the therapeutic potential of a soft thermo-sensitive polymer electroactive hydrogel (TPEH) loaded with nerve growth factor (NGF) combined with functional electrical stimulation (ES) for the treatment of SCI. …”
Publicado 2021
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1993por Tang, S., Salazar-Puerta, A., Richards, J., Khan, S., Hoyland, J.A., Gallego-Perez, D., Walter, B., Higuita-Castro, N., Purmessur, D.“…FOXF1 transfection significantly altered gene expression by upregulating healthy NP markers [FOXF1, keratin 19 (KRT19)], decreasing inflammatory cytokines [interleukin (IL)-1β, −6], catabolic enzymes [metalloproteinase 13 (MMP13)] and nerve growth factor (NGF), with significant increases in glycosaminoglycan accumulation in human NP cells. …”
Publicado 2021
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1994por Wang, Haiyang, Zhao, Xiaojing, Cui, Xiufang, Wang, Meifeng, Jiao, Chunhua, Li, Jiajia, Yang, Yan, Li, Yi, Zhang, Hongjie“…The serum levels of 5-hydroxytryptamine (5-HT) and nerve growth factor (NGF) were measured by enzyme-linked immunosorbent assay. …”
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1995“…Focused cytokine profiling indicated global upregulation in IH of all 31 biomolecules tested in comparison to AO and P with basic-nerve growth factor (bNGF) and granulocyte colony-stimulating factor (GCSF) (>3 fold vs AO) and bNGF and Rantes (>3 fold vs P) of note. …”
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1996“…Single intradermal injections of nerve growth factor (NGF) evoke prolonged but temporally distinct sensitization patterns to somatosensory stimuli. …”
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1997por Casini, Arianna, Mancinelli, Romina, Mammola, Caterina Loredana, Pannarale, Luigi, Chirletti, Piero, Onori, Paolo, Vaccaro, Rosa“…Finally, we used the low-affinity nerve growth factor receptor (p75NTR), to detect peripheral EGCs. …”
Publicado 2021
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1998por Farahani, Zahra K., Taherianfard, Mahnaz, Naderi, Mohamad Mehdi, Ferrero, Hortensia“…The levels of Brain‐derived neurotrophic factor (BDNF), nerve growth factor (NGF), substance P, and calcitonin gene‐related peptide (CGRP) were measured by enzyme‐linked immunosorbent assay. …”
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1999por Liu, Yi‐jun, Chen, Xiao‐feng, Zhou, Li‐ping, Rao, Feng, Zhang, Dian‐ying, Wang, Yan‐hua“…In vitro, Wnt5a could promote SC proliferation and the gene expression of vascular endothelial growth factor (VEGF), nerve growth factor (NGF), and cholinergic neurotrophic factor (CNTF), as well as the protein secretion of VEGF and NGF. …”
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2000por García-Silva, Susana, Benito-Martín, Alberto, Nogués, Laura, Hernández-Barranco, Alberto, Mazariegos, Marina S., Santos, Vanesa, Hergueta-Redondo, Marta, Ximénez-Embún, Pilar, Kataru, Raghu P., Lopez, Ana Amor, Merino, Cristina, Sánchez-Redondo, Sara, Graña-Castro, Osvaldo, Matei, Irina, Nicolás-Avila, José Ángel, Torres-Ruiz, Raúl, Rodríguez-Perales, Sandra, Martínez, Lola, Pérez-Martínez, Manuel, Mata, Gadea, Szumera-Ciećkiewicz, Anna, Kalinowska, Iwona, Saltari, Annalisa, Martínez-Gómez, Julia M., Hogan, Sabrina A., Saragovi, H. Uri, Ortega, Sagrario, Garcia-Martin, Carmen, Boskovic, Jasminka, Levesque, Mitchell P., Rutkowski, Piotr, Hidalgo, Andrés, Muñoz, Javier, Megías, Diego, Mehrara, Babak J., Lyden, David, Peinado, Héctor“…We found that small EVs (sEVs) derived from metastatic melanoma cell lines were enriched in nerve growth factor receptor (NGFR, p75NTR), spread through the lymphatic system and were taken up by lymphatic endothelial cells, reinforcing lymph node metastasis. …”
Publicado 2021
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