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2101por Larner, Stephen F, Wang, Jonathan, Goodman, Jared, O’Donoghue Altman, Megan B, Xin, Meiguo, Wang, Kevin K W“…The incorporations of the nanoparticles into cell cytoplasm were observed using the fluorescent dye-doped NSs in both nondifferentiated and nerve growth factor (NGF)-differentiated PC-12 cells. When PC-12 cells are differentiated, they appeared to be even more sensitive to cytotoxicity of nanoparticles such as CB 10 nm (10–100 µg/mL), CB 100 nm (10–100 µg/mL), and CdSe (1–10 µg/mL).…”
Publicado 2017
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2102por Oses, Carolina, Olivares, Belén, Ezquer, Marcelo, Acosta, Cristian, Bosch, Paul, Donoso, Macarena, Léniz, Patricio, Ezquer, Fernando“…Furthermore this preconditioning increased the expression of potent neuroprotective factors, including nerve growth factor, glial cell-derived neurotrophic factor and neurotrophin-3, and cytokines with anti-inflammatory activity like IL4 and IL5. …”
Publicado 2017
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2103por Sainoh, Takeshi, Inage, Kazuhide, Orita, Sumihisa, Koda, Masao, Furuya, Takeo, Yamauchi, Kazuyo, Suzuki, Miyako, Sakuma, Yoshihiro, Kubota, Go, Oikawa, Yasuhiro, Sato, Jun, Fujimoto, Kazuki, Shiga, Yasuhiro, Abe, Koki, Kanamoto, Hirohito, Inoue, Masahiro, Kinoshita, Hideyuki, Norimoto, Masaki, Umimura, Tomotaka, Takahashi, Kazuhisa, Ohtori, Seiji“…OVERVIEW OF LITERATURE: Low back pain (LBP) is associated with inflammatory cytokine expression levels, including those of tumor necrosis factor-alpha (TNF-α), interleukin 6 (IL-6), and nerve growth factor (NGF). However, the association between cytokine expression levels and the physiological mechanisms of disk degeneration and clinical pain remain controversial. …”
Publicado 2017
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2104por Shu, Chenglin, Huang, Weiqiang, Zeng, Zhiyu, He, Yan, Luo, Beibei, Liu, Hao, Li, Jinyi, Xu, Jian“…The expression levels of nerve growth factor (NGF) and tyrosine hydroxylase (TH) in the atrial tissues were detected using immunohistochemical staining. …”
Publicado 2017
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2105“…Additionally, targets of miR-326 were primarily enriched in the GO terms of cell proliferation, epithelial growth factor receptor and nerve growth factor signaling pathways. Additionally, son of sevenless homolog 1 (SOS1), neuroblastoma RAS viral oncogene homolog (NRAS), vitamin D receptor (VDR) and mothers against decapentaplegic family member 3 (SMAD3) were most enriched in the PPI network. …”
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2106por Shimada, Hiroki, Kogure, Naotaka, Noro, Erika, Kudo, Masataka, Sugawara, Kaori, Sato, Ikuko, Shimizu, Kyoko, Kobayashi, Makoto, Suzuki, Dai, Parvin, Rehana, Saito‐Ito, Takako, Uruno, Akira, Saito‐Hakoda, Akiko, Rainey, William E., Ito, Sadayoshi, Yokoyama, Atsushi, Sugawara, Akira“…Transient transfection studies using deletion mutants/nerve growth factor‐induced clone B (NGFIB) response element 1 (NBRE‐1) point mutant of CYP11B2 5′‐flanking region revealed that the NBRE‐1 element, known to be activated by transcription factors NGFIB and NURR1, was responsible for the high glucose‐mediated effect. …”
Publicado 2017
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2107por Minnone, Gaetana, Soligo, Marzia, Caiello, Ivan, Prencipe, Giusi, Manni, Luigi, Marafon, Denise Pires, Magni-Manzoni, Silvia, Manzo, Antonio, Benedetti, Fabrizio De, Bracci-Laudiero, Luisa“…OBJECTIVE: To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis inflammation. …”
Publicado 2017
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2108por Morelli, Annamaria, Sarchielli, Erica, Guarnieri, Giulia, Coppi, Elisabetta, Pantano, Daniela, Comeglio, Paolo, Nardiello, Pamela, Pugliese, Anna M., Ballerini, Lara, Matucci, Rosanna, Ambrosini, Stefano, Castronovo, Giuseppe, Valente, Rosa, Mazzanti, Benedetta, Bucciantini, Sandra, Maggi, Mario, Casamenti, Fiorella, Gallina, Pasquale, Vannelli, Gabriella B.“…The hfNBMs cholinergic phenotype was regulated by the nerve growth factor (NGF), through the activation of the high-affinity NGF receptor TrkA, as well as by 17-β-estradiol through a peculiar recruitment of its own receptors. …”
Publicado 2017
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2109por Klaassen, Ingeborg, de Vries, Ewout W., Vogels, Ilse M. C., van Kampen, Antoine H. C., Bosscha, Machteld I., Steel, David H. W., Van Noorden, Cornelis J. F., Lesnik-Oberstein, Sarit Y., Schlingemann, Reinier O.“…RESULTS: Of the 507 proteins screened, 21 were found to be significantly elevated in PDR patients, including neurogenic and angiogenic factors such as neuregulin 1 (NRG1), nerve growth factor receptor (NGFR), placental growth factor (PlGF) and platelet derived growth factor (PDGF). …”
Publicado 2017
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2110“…Among mediators involved in OA pain, nerve growth factor (NGF) is in the focus because antibodies against NGF significantly reduce OA pain. …”
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2111por Banks, Dallas A., Dahal, Arya, McFarland, Alexander G., Flowers, Brittany M., Stephens, Christina A., Swack, Benjamin, Gugssa, Ayele, Anderson, Winston A., Hinton, Shantá D.“…In addition, in response to nerve growth factor (NGF), MK-STYX-expressing cells produced more growth cones than non-MK-STYX-expressing cells, further supporting a model in which MK-STYX has a role in actin signaling. …”
Publicado 2017
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2112“…Direct comparison of the secretion of selected cytokines by BM-MSCs and AD-MSCs revealed that significantly higher levels of nerve growth factor and transforming growth factor-β1 were secreted in the AD-MSC culture medium, whereas levels of vascular endothelial growth factor and interleukin-10 did not differ significantly between AD-MSCs and BM-MSCs. …”
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2113por Huang, Li, Li, Zongyi, Tian, Haibin, Wang, Weiguo, Cui, Dawei, Zhou, Zhe, Chen, Xiao, Cheung, Herman S., Xu, Guo-tong, Chen, Yu“…The percentage of terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive apoptotic photoreceptors was significantly lower in the hPDLSC-injected retinas than in those of the control groups. hPDLSCs were also found to express multiple neurotrophic factors, including vascular endothelial growth factor, bioactive basic fibroblast growth factor, brain-derived neurotrophic factor, neurotrophin-3, insulin-like growth factor 1, nerve growth factor, and glial cell line-derived neurotrophic factor. …”
Publicado 2017
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2114por Zhang, Min, Zhou, Qiang, Luo, Yuncin, Nguyen, Tara, Rosenblatt, Mark I., Guaiquil, Victor H.“…We then corroborated that Sema3A totally abolished the growth promoting effect of nerve growth factor (NGF) on embryonic neurons and observed signs of growth cone collapse and axonal retraction after 30 min of Sema3A addition. …”
Publicado 2018
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2115por Becker, Silke, Wang, Haibo, Simmons, Aaron B., Suwanmanee, Thipparat, Stoddard, Gregory J., Kafri, Tal, Hartnett, M. Elizabeth“…Erythropoietin (EPO), brain-derived neurotrophic factor, glial-derived neurotrophic factor, nerve growth factor, neurotrophin-3 (NT-3) mRNAs were increased in L-VEGFAshRNA, but not L-VEGF164shRNA retinas. …”
Publicado 2018
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2116“…In mouse MCAO, PAP‐1 dose‐dependently reduced infarct area, improved neurological deficit score, and reduced brain levels of IL‐1β and IFN‐γ without affecting IL‐10 and brain‐derived nerve growth factor (BDNF) levels or inhibiting ongoing phagocytosis. …”
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2117por Bleedorn, Jason A., Hornberger, Troy A., Goodman, Craig A., Hao, Zhengling, Sample, Susannah J., Amene, Ermias, Markel, Mark D., Behan, Mary, Muir, Peter“…Western blot analysis of bone for MAPK’s, PI3K/Akt, and mTOR signaling, and quantitative reverse transcription polymerase chain reaction (qRT-PCR) to estimate gene expression of calcitonin gene-related protein alpha (CGRP-α), brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), c-jun, and c-fos in dorsal root ganglion (DRG) of the brachial intumescence were performed. …”
Publicado 2018
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2118por Ohkouchi, Chiyo, Kumamoto, Kensuke, Saito, Motonobu, Ishigame, Teruhide, Suzuki, Shin-Ichi, Takenoshita, Seiichi, Harris, Cutis C.“…In addition to MMP13 and PAI-1, eight genes [heat shock protein family A member 1A (HSPA1A), MIR7-3 host gene, chorionic somatomammotropin hormone 1, growth arrest and DNA damage inducible b, dehydrogenase/reductase 2, galectin 1, myosin light chain 1, and VGF nerve growth factor inducible] were demonstrated to be associated with ING2/HDAC1. …”
Publicado 2017
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2119por Scandolera, Amandine, Hubert, Jane, Humeau, Anne, Lambert, Carole, De Bizemont, Audrey, Winkel, Chris, Kaouas, Abdelmajid, Renault, Jean-Hugues, Nuzillard, Jean-Marc, Reynaud, Romain“…Transcriptomic analysis performed on ≈100 genes related to skin biological functions firstly revealed that the crude Rhodosorus marinus extract was able to significantly negatively modulate specific genes involved in pro-inflammation (interleukin 1α encoding gene, IL1A) and pain detection related to tissue inflammation (nerve growth factor NGF and its receptor NGFR). An in vitro model of normal human keratinocytes was then used to evaluate the ability of the Rhodosorus marinus extract to control the release of neuro-inflammation mediators under phorbol myristate acetate (PMA)-induced inflammatory conditions. …”
Publicado 2018
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2120por Sobuś, Anna, Baumert, Bartłomiej, Litwińska, Zofia, Gołąb-Janowska, Monika, Stępniewski, Jacek, Kotowski, Maciej, Pius-Sadowska, Ewa, Kawa, Miłosz P., Gródecka-Szwajkiewicz, Dorota, Peregud-Pogorzelski, Jarosław, Dulak, Józef, Nowacki, Przemysław, Machaliński, Bogusław“…Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular endothelial growth factor (VEGF)) and in the immune modulating features, in particular, the anti-inflammatory effects. …”
Publicado 2018
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