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Mostrando 721 - 740 Resultados de 2,475 Para Buscar '"nerve growth factor"', tiempo de consulta: 0.20s Limitar resultados
  1. 721
    por Dray, Andy, Read, Simon J
    Publicado 2007
    “…We highlight opportunities for targeting inflammatory mediators and their key receptors (for example, prostanoids, kinins, cytokines and chemokines), ion channels (for example, NaV1.8, NaV1.7 and CaV2.2) and neurotrophins (for example, nerve growth factor), noting evidence that relates to their participation in OA etiology and treatment. …”
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    Arthritis and pain. Future targets to control osteoarthritis pain
  2. 722
    por Yang, Xiaojing, Ren, Hanru, Fu, Jie
    Publicado 2021
    “…In recent years, some scholars have tried to treat RBN with bevacizumab, nerve growth factor, and gangliosides and have achieved similar results. …”
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    Treatment of Radiation-Induced Brain Necrosis
  3. 723
    por Covaceuszach, Sonia, Lamba, Doriano
    Publicado 2023
    “…SIMPLE SUMMARY: A point mutation in the Nerve Growth factor gene (leading to the amino acid substitution R100W), causing Hereditary Sensory and Autonomic Neuropathy type V, a condition that primarily affects the sensory nerve cells, whose principal function is to transmit information about sensations, such as pain. …”
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    The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR
  4. 724
    “…BACKGROUND: Nerve growth factor and neurotrophin-3 are involved in the development of sympathetic neurons; however, whether brain derived neurotrophic factor also plays a role is not known. …”
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    Embryonic sympathoblasts transiently express TrkB in vivo and proliferate in response to brain-derived neurotrophic factor in vitro
  5. 725
    Publicado 1986
    “…The levels of both MAP1-specific and MAP2-specific mRNAs decline in the postnatal developing brain; the level of MAP1-specific mRNA also increases slightly in rat PC12 cells upon exposure to nerve growth factor. These surprising results contrast sharply with reported dramatic developmental increases in the amount of MAP1 in brain and in nerve growth factor-induced PC12 cells. …”
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    A cloned cDNA encoding MAP1 detects a single copy gene in mouse and a brain-abundant RNA whose level decreases during development
  6. 726
    Publicado 1990
    “…Several groups have shown that PC12 will extend microtubule-containing neurites on extracellular matrix (ECM) with no lag period in the absence of nerve growth factor. This is in contrast to nerve growth factor (NGF)-induced neurite outgrowth that occurs with a lag period of several days. …”
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    Extracellular matrix allows PC12 neurite elongation in the absence of microtubules
  7. 727
    “…In particular, we examine the research looking at insulin, insulin-like growth factor, vascular endothelial growth factor, pigment epithelium-derived growth factor, brain-derived neurotrophic factor, and nerve growth factor. RESULTS: Research shows that insulin has neurotrophic properties and that the loss of its pro-survival pathways may have a role in diabetic retinopathy. …”
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    Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far
  8. 728
    “…As shown for past variants in this region, T546A impairs SH2B1β enhancement of nerve growth factor-induced neurite outgrowth, and the individual with the T546A variant exhibits mild developmental delay. …”
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    Functional Characterization of Obesity-Associated Variants Involving the α and β Isoforms of Human SH2B1
  9. 729
    “…Here we report that EVT901 reduces binding of pro-nerve growth factor to p75 neurotrophin receptor, blocks pro-nerve growth factor induced apoptosis in cells expressing p75 neurotrophin receptor, and enhances neurite outgrowth in vitro. …”
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    A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury
  10. 730
    “…CONCLUSIONS: The identification of higher NIHSS scores, higher HAMD scores, lower dopamine level, lower 5-hydroxytryptamine level, higher tumor necrosis factor-α level, and lower nerve growth factor level might be useful for clinicians in recognizing and treating depression in patients after a stroke.…”
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    Predictors of early-onset post-ischemic stroke depression: a cross-sectional study
  11. 731
    “…Compared with the MI group, mRNA and protein levels of tyrosine hydroxylase and growth associated protein-43, as well as choline acetyltransferase mRNA level significantly decreased in the MI plus NRG-1 group, while mRNA and protein levels of nerve growth factor and vesicular acetylcholine transporters, as well as choline acetyltransferase protein level slightly decreased. …”
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    Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model
  12. 732
    “…RESULTS: Adiposity was related to higher nerve growth factor, hepatic growth factor, migration inhibitory factor, leptin and adipsin and with lower chemerin, plasminogen activator inhibitor-1, resistin, plasma amyloid A1 and adiponectin. …”
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    The relation between body fat distribution, plasma concentrations of adipokines and the metabolic syndrome in patients with clinically manifest vascular disease
  13. 733
    “…Acetylcholinesterase (AchE) assay showed that both FGD and CCAD inhibited AchE activity in nerve growth factor-differentiated neuronal-like PC12 cells to 89.1% and 74.5% of that in non-treated cells, respectively. …”
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    Enzyme-digested Colla Corii Asini (E’jiao) prevents hydrogen peroxide-induced cell death and accelerates amyloid beta clearance in neuronal-like PC12 cells
  14. 734
    “…Nerve Growth Factor (NGF) was initially studied for its role as a key player in the regulation of peripheral innervations. …”
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    NGF, Brain and Behavioral Plasticity
  15. 735
    “…Abbreviations: IOP = intraocular pressure, NO = nitric oxide, NOS = nitric oxide synthase, ROCK = coiled coil-forming protein kinase, RCG = retinal ganglion cells, NGF = nerve growth factor.…”
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    Biochemical changes and treatment in glaucoma
  16. 736
    “…Our results suggest that IFN‐γ can modulate the signal transduction of nerve growth factor in human neuroblastoma cells.…”
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    Increased Expression of trk Proto‐oncogene by γ‐Interferon in Human Neuroblastoma Cell Lines
  17. 737
    por Renz, Harald
    Publicado 2001
    “…We have therefore developed the concept that neurotrophins such as nerve growth factor and brain-derived neurotrophic factor link pathogenic events in BA to dysfunctions of the immune and nervous system.…”
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    Neurotrophins in bronchial asthma
  18. 738
    “…As a result, nepalactone A derivative 1c and nepalarin (3) significantly enhanced nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells.…”
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    Picrotoxane Sesquiterpene Glycosides and a Coumarin Derivative from Coriaria nepalensis and Their Neurotrophic Activity
  19. 739
    “…It has the ability to differentiate in the presence of nerve growth factor (NGF), resulting in neural extensions called dendrites and axons. …”
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    Guiding neural extensions of PC12 cells on carbon nanotube tracks dielectrophoretically formed in poly(ethylene glycol) dimethacrylate
  20. 740
    “…In addition, they noticeably enhanced the neurite outgrowth of nerve growth factor (NGF) mediated PC12 cells at a concentration of 10 μM.…”
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    Antiacetylcholinesterase triterpenes from the fruits of Cimicifuga yunnanensis
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