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1041por Xu, Pengfei, Shi, Xiaolei, Zhang, Xiaohao, Liu, Qian, Xie, Yi, Hong, Ye, Li, Juanji, Peng, Mengna, Liu, Xinfeng, Xu, Gelin“…Further, the transplantation of BRCA1-transfected NSCs into mice with ischemic stroke increased brain-derived neurotropic factor and nerve growth factor expression in the brain and elicited neurological function improvement. …”
Publicado 2019
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1042por Vincent, Tonia L.“…It drives synovitis and can induce other disease-relevant genes such as nerve growth factor, a key pain sensitiser in OA. However, the quality of evidence for its involvement in disease is modest. …”
Publicado 2019
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1043por Lin, Na, Dong, Xiu-Juan, Wang, Ting-Yong, He, Wen-Ji, Wei, Jing, Wu, Hai-Ying, Wang, Ting-Hua“…The present study used western blot analysis to identify antibody specificity in protein extracts from whole tree shrew brains to identify the specificity of p75 nerve growth factor receptor (NGFR) derived from rabbits (75 kDa). …”
Publicado 2019
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1044por Hsu, Ru‐Siou, Chen, Pei‐Yueh, Fang, Jen‐Hung, Chen, You‐Yin, Chang, Chien‐Wen, Lu, Yu‐Jen, Hu, Shang‐Hsiu“…By embedding gradient concentrations of growth factors into the building blocks, the propagated gradient of the nerve growth factor, integrated to the cell‐penetrative connected pores constructed by the building blocks in the nerve conduit, effectively promotes cell migration and induces dramatic bridging effects on peripheral nerve defects, achieving axon outgrowth of up to 4.7 mm and twofold axon fiber intensity in 4 days in vivo. …”
Publicado 2019
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1045por Bhattarai, Prabesh, Cosacak, Mehmet Ilyas, Mashkaryan, Violeta, Demir, Sevgican, Popova, Stanislava Dimitrova, Govindarajan, Nambirajan, Brandt, Kerstin, Zhang, Yixin, Chang, Weipang, Ampatzis, Konstantinos, Kizil, Caghan“…BDNF enhances NSC plasticity and neurogenesis via nerve growth factor receptor A (NGFRA)/ nuclear factor 'kappa-light-chain-enhancer' of activated B-cells (NFkB) signaling in zebrafish but not in rodents. …”
Publicado 2020
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1046por Enes, Joana, Haburčák, Marián, Sona, Surbhi, Gerard, Nega, Mitchell, Alexander C., Fu, Wenqi, Birren, Susan J.“…Cultured satellite glia make and release factors that promote neuronal activity and that can partially rescue the neurons from cell death following nerve growth factor deprivation. Thus, satellite glia play an early and ongoing role within the postnatal sympathetic ganglia, expanding our understanding of the contributions of local and target-derived factors in the regulation of sympathetic neuron function.…”
Publicado 2020
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1047por Carrero-Rojas, Génova, Benítez-Temiño, Beatriz, Pastor, Angel M., Davis López de Carrizosa, Mª América“…Our quantitative analysis of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and neurotrophin-3 (NT-3) transcripts showed, for the first time, that EOMs-derived cells express more of these factors and that they expressed TrkA, but not TrkB and TrkC receptors. …”
Publicado 2020
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1048“…While the nutritional factor (L‐glutamine, NGF (nerve growth factor), bFGF (basic fibroblast growth factor), IGF‐1 (insulin‐like growth factor‐1) and EGF (epidermal growth factor)) additives were prior to induce the PDLSCs into neuronal differentiation. …”
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1049“…Human nerve growth factor β (β-NGF) is considered a major therapeutic agent for treatment of neurodegenerative diseases. …”
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1050“…Likewise, we report herein that NTP prevented the neurite retraction in PC12 cells by nerve growth factor (NGF) deprivation. This effect was accompanied by interaction of Fyn with high-affinity NGF receptor TrkA. …”
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1051por Grégory, Pourié, Nassila, Akchiche, Jean-Louis, Millot, Jean-Louis, Guéant, Jean-Luc, Daval, Carine, Bossenmeyer-Pourié“…It is known that plated OPs respond to various trophic factors, and we also showed that the use of Nerve Growth Factor (NGF) allowed switching from a 60/40 neuron/glia ratio to an 80/20 one. …”
Publicado 2020
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1052Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer’s Diseasepor Yu, Jin, Zhu, Hong, Taheri, Saeid, Mondy, William, Perry, Stephen, Kirstein, Cheryl, Kindy, Mark S.“…Additionally, treatment with GF diets increased nerve growth factor (NGF) levels in the brain and tempered the memory impairment in the animal model. …”
Publicado 2020
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1053“…Neurogenesis is a complex process involving multiple factors, among which nerve growth factor (NGF) possesses the dual biological roles of neuron nutrition and axon growth promotion. …”
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1054“…In addition, the polysaccharide suppressed the decrease in the expression levels of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). These findings strongly suggest that the polysaccharide in the nacre extract mediated its antiamnesic effects by preventing oxidative stress and inflammation and increasing the expression levels of BDNF and NGF.…”
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1055“…Among the far infrared-exposed AD mice, body weights were significantly decreased, and the levels of nerve growth factor and brain-derived neurotrophic factor protein were significantly increased in selected brain areas (compared to those in non-irradiated AD mice). …”
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1056por Perri, Anna, Rago, Vittoria, Malivindi, Rocco, Maltese, Lorenza, Lofaro, Danilo, Greco, Emanuela Alessandra, Tucci, Luigi, Bonofiglio, Renzo, Vergine, Margherita, La Vignera, Sandro, Chiefari, Eusebio, Brunetti, Antonio, Aversa, Antonio“…Several studies have demonstrated that the p75(NTR) low-affinity receptor of Nerve Growth Factor (NGF), is produced in abnormally large amounts in several human cancer types. …”
Publicado 2021
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1057“…PC12 cells were plated directly onto a CorMatrix flake or the well surface of a 12-well plate and cultured in RPMI-1640 medium and a medium supplemented with the nerve growth factor (NGF). The surface of the culture plates was modified with collagen type I (Col I). …”
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1058“…At the microenvironment of SCI, stem cells are capable of producing growth factors like brain-derived neurotrophic factor and nerve growth factor which triggers neuronal survival as well as axonal regrowth. …”
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1059por Poulaki, Smaragda, Rassouli, Olga, Liapakis, George, Gravanis, Achille, Venihaki, Maria“…Its synthetic, 17-spiro-epoxy analogue, BNN27, cannot be converted to estrogen or androgen as DHEA; it is a specific agonist of TrkA, the receptor of pain regulator Nerve Growth Factor (NGF), and it conserves the immunomodulatory properties of DHEA. …”
Publicado 2021
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1060“…Importantly, there is no pharmacological therapy with nerve growth factor for monkeys after SCI; thus, in this study, the changes that occurred in the brain were spontaneous. …”
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