“…As a result, all candidate and mapped biotargets of calycosin and meningitis were harvested before the vital targets of epidermal growth factor receptor (EGFR), tumor necrosis factor (TNF), epidermal growth factor (EGF), ataxia telangiectasia mutated protein (ATM), estrogen receptor alpha (ESR1), caspase-8 (CASP8), nerve growth factor (NGF) of calycosin-anti-meningitis were identified. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Western blot and RT-PCR results showed that the expression levels of type-Ⅰ and Ⅲ collagen in the PCL-treated rats were half of those in the control group after 12 weeks, while the expression level of nerve growth factor was approximately 3.5 times that found in the rats treated with medical chitosan hydrogel. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We have previously reported that phytochemicals from Abies holophylla exhibit anti-inflammatory and neuroprotective effects by decreasing nitrite production and increasing nerve growth factor production. However, the exact mechanism underscoring these effects has not been revealed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are trophic factors required by distinct population of sensory neurons during development of the nervous system. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…NPD1 stimulates the synthesis of brain-derived neurotrophic factor, nerve growth factor, and semaphorin 7A. RvD6i treatment of injured corneas modulates gene expression in the TG resulting in enhanced neurogenesis, decreased neuropathic pain, and increased sensitivity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The aims of our study were to evaluate the neuroprotective potential of viniferin in the nerve growth factor (NGF)-differentiated PC12 cells, a dopaminergic cellular model of Parkinson’s disease (PD) and assess its anti-inflammatory properties in a N9 microglia–neuronal PC12 cell co-culture system. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, IBC increased the expression of brain-derived neurotrophic factor and nerve growth factor. Furthermore, IBC inhibited the loss and induced the production of synaptophysin, a major synaptic vesicle protein. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, PNSCs showed therapeutic potential by releasing the neurotrophic factors, including glial cell-line-derived neurotrophic factor, insulin-like growth factor, nerve growth factor, and neurotrophin-3. PNSC abilities were also enhanced by their development into spheroids which secreted neurotrophic factors several times more than non-spheroid PNSCs and expressed several types of extra cellular matrix. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Upon activation, muscle glial–derived progenies expressed neurotrophic genes, including nerve growth factor receptor, which enables their isolation by FACS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, the expression of pain‐related inflammatory markers, such as nerve growth factor, cyclooxygenase‐2, and interleukin‐6 in the biopsied bladder tissues was significantly lower when the drug‐delivery IUC was used. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The present study proposes to combine chitosan benefic properties to the nanoparticles’ ability to transport different substances to specific locations and evaluate the effects of magnetic nanoparticles functionalized with chitosan (CMNPs) on peripheral nerve injuries’ rehabilitation by using an in vivo experimental model. (2) Methods: CMNPs treatment was administrated daily, orally, for 21 days to rats subjected to right sciatic nerve lesion and compared to the control group (no treatment) by analyzing the sciatic functional index, pain level, body weight, serum nerve growth factor levels and histology, TEM and EDX analysis at different times during the study. (3) Results: Animals treated with CMNPs had a statistically significant functional outcome compared to the control group regarding: sciatic functional index, pain-like behavior, total body weight, which were confirmed by the histological and TEM images. (4) Conclusions: The results of the study suggest that CMNPs appear to be a promising treatment method for peripheral nerve injuries.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We compare the outgrowth potential of Tet3 microspheres with that of commonly used nerve growth factor (NGF)‐loaded microspheres in an in vitro injury model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…P-CTX-2 increased the release of nerve growth factor and brain-derived neurotrophic factor in the co-culture supernatant, suggesting that those neurotrophins could contribute to the sensitization of the aforementioned receptors and channels. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nerve growth factor (NGF) and its precursor form, proNGF, are critical for neuronal survival and cognitive function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our previous research has confirmed that poly(D, L-lactic acid)/β-tricalcium phosphate/hyaluronic acid/chitosan/nerve growth factor (PDLLA/β-TCP/HA/CHS/NGF) NGCs have excellent physical and chemical properties, which can slowly release NGF and support cell adhesion and proliferation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Embryonic rat neural stem cells and primary neurons were maturated with either nerve growth factor, trans-retinoic acid or activators of cAMP-dependent protein kinase A (dibutyryl-cAMP, forskolin, theophylline). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Eye-drop recombinant human nerve growth factor (ed-rhNGF) has proved to recover the retina and optic nerve damage in animal models, including the unilateral optic nerve crush (ONC), and to improve visual acuity in humans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A thermo-ionically crosslinked gellan-xanthan hydrogel conduit loaded with electrospun PHBV-magnesium oleate-N-acetyl-cysteine (PHBV-MgOl-NAC) nanofibers was assessed for mechanical properties, nerve growth factor (NGF) release kinetics and PC12 viability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Many scalarane sesterterpenoids displayed a wide spectrum of valuable properties, such as antifeedant, antimicrobial, antifungal, antitubercular, antitumor, anti-HIV properties, cytotoxicity and stimulation of nerve growth factor synthesis, as well as anti-inflammatory activity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After 8 weeks of combined treatment, the autotomy behaviors were reduced in rats subjected to sciatic nerve transfection, the mRNA expression of nerve growth factor, a pain marker, in the proximal nerve stump was decreased, the density of regenerated axons was decreased, the thickness of the myelin sheath was increased, and the ratio of unmyelinated to myelinated axons was reduced. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso