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1341por Baumeister, David, Eich, Wolfgang, Saft, Silvia, Geisel, Olga, Hellweg, Rainer, Finn, Anja, Svensson, Camilla I., Tesarz, Jonas“…This cross-sectional study set out to assess and compare brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in plasma samples from fibromyalgia patients and healthy controls. …”
Publicado 2019
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1342por Nan, Ligang, Qin, Tao, Xiao, Ying, Qian, Weikun, Li, Jie, Wang, Zheng, Ma, Jiguang, Ma, Qingyong, Wu, Zheng“…We found that HGF promotes PC cell migration and invasion by activating the HGF/c-Met pathway, and enhances the expression of nerve growth factor (NGF) and matrix metalloproteinase-9 (MMP9) in vitro. …”
Publicado 2019
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1343“…Nerve growth factor (NGF) is thought to play a key role in chronic pain felt by bladder pain syndrome/interstitial cystitis (BPS/IC) patients by activating its high affinity receptor tropomyosin-related kinase subtype A (Trk A). …”
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1344por Matsuzaki, Yuka, Maruta, Rina, Takaki, Keiko, Kotani, Eiji, Kato, Yasuko, Yoshimura, Ryoichi, Endo, Yasuhisa, Whitty, Ciara, Pernstich, Christian, Gandhi, Raj, Jones, Michael, Mori, Hajime“…Specifically, when nerve growth factor (NGF), a neurotrophin, was encapsulated into nanoparticles, its release was promoted by MMPs secreted by a PC12 neuronal cell line. …”
Publicado 2019
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1345“…Moreover, an increased expression of nerve growth factor (NGF) and vascular endothelial growth factor (VEGF) also contribute in Koebernization. …”
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1346por Garrido, Maritza P., Hurtado, Iván, Valenzuela-Valderrama, Manuel, Salvatierra, Renato, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen“…Epithelial ovarian cancer (EOC) is a lethal gynecological neoplasia characterized by extensive angiogenesis and overexpression of nerve growth factor (NGF). Here, we investigated the mechanism by which NGF increases vascular endothelial growth factor (VEGF) expression and the vasculogenic potential of EOC cells, as well as the contribution of the cyclooxygenase 2/prostaglandin E(2) (COX-2/PGE(2)) signaling axis to these events. …”
Publicado 2019
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1347por Li, Liheng, Cai, Jing, Yuan, Yang, Mao, Yanyan, Xu, Lei, Han, Yuechen, Li, Jianfeng, Wang, Haibo“…Polymerase chain reaction results showed that PRP releases growth factors, which include nerve growth factor and brain-derived neurotrophic factor. …”
Publicado 2019
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1348por Xhima, K., Markham-Coultes, K., Nedev, H., Heinen, S., Saragovi, H. U., Hynynen, K., Aubert, I.“…In animal models of injury and aging, nerve growth factor (NGF) enhances cholinergic cell survival and function, contributing to improved memory. …”
Publicado 2020
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1349por Lang Balija, Maja, Leonardi, Adrijana, Brgles, Marija, Sviben, Dora, Kurtović, Tihana, Halassy, Beata, Križaj, Igor“…Using a proteomics approach, we have identified 25 proteins in the venom that belong to seven protein families: snake venom metalloproteinase, serine protease, secreted phospholipase A(2), cysteine-rich secretory protein, snake C-type lectin-like protein, serine protease inhibitor and nerve growth factor. The Vipera ursinii ssp. venom was found to be distinctively insecticidal. …”
Publicado 2020
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1350“…Pain was treated mostly by antagonizing nerve growth factor (NGF) activity and its receptor tropomyosin-related kinase A (TrkA). …”
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1351por Zhang, Xiaohui, Muddana, Santosh, Kumar, Sangeetha Ravi, Burton, Joshua Nelson, Labroo, Pratima, Shea, Jill, Stocking, Parker, Siegl, Cornelia, Archer, Bonnie, Agarwal, Jayant, Ambati, Balamurali K.“…PURPOSE: Neurotrophic keratopathy is a degenerative disease that may be improved by nerve growth factor (NGF). Our aim was to investigate the use of pergolide, a dopamine (D1 and D2) receptor agonist known to increase the synthesis and release of NGF for regeneration of damaged corneal nerve fibers. …”
Publicado 2020
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1352“…Herein, we focus on that the Nerve growth factor (NGF)/Tropomyosin‐related kinase A (TrkA), in pancreatic stellate cells‐pancreatic cancer cells (PSCs‐PC cells) co‐culture system, influences PC proliferation and invasion. …”
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1353por Liu, Bonan, Kou, Jiayuan, Li, Fuyan, Huo, Da, Xu, Jiaran, Zhou, Xiaoxi, Meng, Dehao, Ghulam, Murtaza, Artyom, Bobkov, Gao, Xu, Ma, Ning, Han, Dong“…The effects of LEO on learning and memory were examined using the Morris Water Maze (MWM) test, Novel object recognition test, and correlative indicators, including a neurotransmitter (acetylcholinesterase, AChE), a nerve growth factor (brain-derived neurotrophic factor, BDNF), a postsynaptic marker (PSD95), and presynaptic markers (synapsin-1, and synaptophysin), in APP/PS1 mice. …”
Publicado 2020
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1354por Habib, Abdella M., Nagi, Karim, Thillaiappan, Nagendra Babu, Sukumaran, VijayaKumar, Akhtar, Saghir“…In this review, we discuss pathways involved in pain sensing and processing primarily at the level of dorsal root ganglion (DRG) neurons and the potential interplay between vitamin D, its receptor (VDR) and known specific pain signaling pathways including nerve growth factor (NGF), glial-derived neurotrophic factor (GDNF), epidermal growth factor receptor (EGFR), and opioid receptors. …”
Publicado 2020
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1355por Jang, Myung-Soo, Han, Jin Hee, Kim, Dong-Ok, Woo, Gil, Kwon, Jae-Ik, Chung, Jun-Young, Lee, Bong-Jae, Yi, Jae-Woo“…Western blot was used to evaluate the expression level of nerve growth factor (NGF) and myelin basic protein (MBP) in the sciatic nerve. …”
Publicado 2020
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1356“…We also assessed some of the cellular/molecular processes that could be involved in the action of TSA, including the expression of neurotrophic factors (glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and brain-derived neurotrophic factor (BDNF)) as well as the TrkB receptor and its downstream signalling substrate— cAMP response element-binding protein (CREB). …”
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1357“…Compounds 9a, 9h, 9o, and 9q exhibited moderate nerve growth factor (NGF)-mediated neurite-outgrowth promoting effects in PC-12 cells at the concentration of 20 μm. …”
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1358por Atmaramani, Rahul R., Black, Bryan J., de la Peña, June Bryan, Campbell, Zachary T., Pancrazio, Joseph J.“…Here, we demonstrate that the addition of two inflammatory mediators associated with chronic inflammatory pain, nerve growth factor (NGF) and interleukin-6 (IL-6), to adult DRG neurons increases their firing rates on multi-electrode arrays in vitro. …”
Publicado 2020
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1359por Goto, Yoshikuni, Nakamura, Takahiro J., Ogawa, Kenji, Hattori, Akira, Tsujimoto, Masafumi“…Further, synchronously cultured PC12 cells on treatment with nerve growth factor (NGF) showed circadian expression patterns of P-LAP/IRAP and enzymatic activity during 24 h of incubation. …”
Publicado 2020
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1360“…Chromosomal rearrangements involving the NTRK1, NTRK2, and NTRK3 genes (NTRK genes), which encode the high-affinity nerve growth factor receptor (TRKA), brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) growth factor receptor (TRKB), and neurotrophin-3 (NT-3) growth factor receptor (TRKC) tyrosine kinases (TRK proteins), act as oncogenic drivers in a broad range of pediatric and adult tumor types. …”
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