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1381por Kim, Hyunseong, Jeon, Wanjin, Hong, Jinyoung, Lee, Junseon, Yeo, Changhwan, Lee, Yoonjae, Baek, Seungho, Ha, Inhyuk“…In addition, GJD-induced Sirtuin1 activation accelerated elongation of new axons and formation of synapses via increased expression of nerve growth factor and brain-derived neurotrophic factor, as well as regeneration-related genes. …”
Publicado 2021
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1382“…Mechano-transcription of pain mediators such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) may lead to visceral hypersensitivity. …”
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1383por Kusakabe, Takuya, Sawaji, Yasunobu, Endo, Kenji, Suzuki, Hidekazu, Konishi, Takamitsu, Maekawa, Asato, Murata, Kazuma, Yamamoto, Kengo“…The molecular mechanism of discogenic low back pain (LBP) involves nonphysiological nerve invasion into a degenerated intervertebral disc (IVD), induced by nerve growth factor (NGF). Selective cyclooxygenase (COX)-2 inhibitors are mainly used in the treatment of LBP, and act by suppressing the inflammatory mediator prostaglandin E(2) (PGE(2)), which is induced by inflammatory stimuli, such as interleukin-1β (IL-1β). …”
Publicado 2021
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1384por Altunay, İlknur Kıvanç, Özkur, Ezgi, Uğurer, Ece, Baltan, Ecem, Aydın, Çiğdem, Serin, Erdinç“…Levels of neurotrophins (brain-derived neurotrophic factor, neurotrophin-3, nerve growth factor, glial cell line-derived neurotrophic factor) were determined by ELISA assays. …”
Publicado 2021
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1385por Garrido, Maritza P., Vallejos, Christopher, Girardi, Silvanna, Gabler, Fernando, Selman, Alberto, López, Fernanda, Vega, Margarita, Romero, Carmen“…Nerve growth factor (NGF) and its high-affinity receptor TRKA are overexpressed in epithelial ovarian cancer (EOC) displaying a crucial role in the disease progression. …”
Publicado 2022
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1386por Castellini, Cesare, Mattioli, Simona, Cotozzolo, Elisa, Pistilli, Alessandra, Rende, Mario, Bartolini, Desirée, Di Sante, Gabriele, Menchetti, Laura, Dal Bosco, Alessandro, Stabile, Anna Maria“…Background: Nerve Growth Factor (NGF) plays an important role in the reproductive system through its receptor’s interaction (p75(NTR)). …”
Publicado 2022
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1387por Colardo, Mayra, Petraroia, Michele, Lerza, Letizia, Pensabene, Daniele, Martella, Noemi, Pallottini, Valentina, Segatto, Marco“…Recent evidence suggests that nerve growth factor (NGF) may exert neurotrophic activity by influencing cell metabolism. …”
Publicado 2022
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1388por Matta, Ajay, Karim, Muhammad Zia, Gerami, Hoda, Benigno, Bettina Zoe, Cheng, Ivan, Mehrkens, Arne, Erwin, William Mark“…Discs injected with NTG-101 showed significantly lower levels of Nerve Growth Factor receptor (NGFr/TrkA, p = 0.0001), BDNF (p = 0.009), TrkB (p = 0.002) and CALCRL (p = 0.008) relative to PBS injections. …”
Publicado 2022
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1389“…We evaluated whether an increase in brain-derived neurotrophic factor (BDNF) and nerve-growth factor (NGF) levels, through transplantation of choline acetyltransferase (ChAT)-overexpressing neural stem cells (F3.ChAT), improved learning and memory in ovariectomized rats. …”
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1390“…Furthermore, GA obviously reduced the concentration of inflammatory cytokines in the sciatic nerves of diabetic rats and supernatants of high glucose-exposed RSC96 cells, then restored the decreased expression levels of nerve growth factor (NGF) and neuritin-1, and the increased expression levels of cleaved caspase-3 and neuron-specific enolase. …”
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1391por Podvin, Sonia, Jiang, Zhenze, Boyarko, Ben, Rossitto, Leigh-Ana, O’Donoghue, Anthony, Rissman, Robert A., Hook, Vivian“…Neuropeptidomics demonstrated distinct profiles of neuropeptides in AD compared to controls consisting of neuropeptides derived from chromogranin A (CHGA) and granins, VGF (nerve growth factor inducible), cholecystokinin, and others. …”
Publicado 2022
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1392“…Downstream of neurotrophins and their receptors, VGF was identified as a nerve growth factor (NGF)- and BDNF-inducible secreted protein and neuropeptide precursor that is produced and trafficked throughout the CNS, where its expression is greatly influenced by neuronal activity and exercise, and where several VGF-derived peptides modulate neuronal activity, function, proliferation, differentiation, and survival. …”
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1393por Gautier, Benoit, Meneux, Léna, Feret, Nadège, Audrain, Christine, Hudecek, Laetitia, Kuony, Alison, Bourdon, Audrey, Le Guiner, Caroline, Blouin, Véronique, Delettre, Cécile, Michon, Frédéric“…Second, we detect no adverse effect after AAV2/9-mediated nerve growth factor expression in the lacrimal gland. Only a transitory increase in tear flow is measured. …”
Publicado 2022
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1394por Ferraguti, Giampiero, Fanfarillo, Francesca, Tarani, Luigi, Blaconà, Giovanna, Tarani, Francesca, Barbato, Christian, Minni, Antonio, Ralli, Massimo, Francati, Silvia, Greco, Antonio, Petrella, Carla, Fiore, Marco“…In recent studies, the potential role of nerve growth factor (NGF) in male reproductive physiology has been proposed. …”
Publicado 2022
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1395por Biamonte, Filippo, Re, Agnese, Balzamino, Bijorn Omar, Ciasca, Gabriele, Santucci, Daniela, Napodano, Cecilia, Nocca, Giuseppina, Fiorita, Antonella, Marino, Mariapaola, Basile, Umberto, Micera, Alessandra, Callà, Cinzia Anna Maria“…Recent interest has been devoted to some neuronal manifestations and to increased levels of Nerve Growth Factor (NGF) and Brain-derived Neurotrophic Factor (BDNF) in the bloodstream during SARS-CoV-2 infection, neurotrophins that are well-known for their multifactorial actions on neuro-immune-endocrine and visual functions. …”
Publicado 2022
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1396“…Four-day pretreatment with nerve growth factor (NGF) resulted in an inhibitory effect on [(3)H]choline uptake. …”
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1397por Li, Qing, Liu, Wenbin, Hou, Wen, Wu, Xiaopei, Wei, Wenying, Liu, Jiawei, Hu, Yihe, Dai, Honglian“…The sustained release of Mg(2+) in Nd@WH can effectively promote the up-regulation of nerve growth factor (NGF) and vascular endothelial growth factor (VEGF). …”
Publicado 2022
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1398por Marsland, Mark, Dowdell, Amiee, Faulkner, Sam, Jobling, Phillip, Rush, Robert A., Gedye, Craig, Lynam, James, Griffin, Cassandra P., Baker, Mark, Marsland, Joanne, Jiang, Chen Chen, Hondermarck, Hubert“…Temozolomide (TMZ), the standard chemotherapeutic drug used in GBM, has limited benefit and alternate therapies are needed to improve GBM treatment. Nerve growth factor (NGF) and its precursor proNGF are increasingly recognized as stimulators of human tumor progression. …”
Publicado 2023
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1399por Mao, Xiaoyan, Li, Ting, Cheng, Junqiu, Tao, Meihan, Li, Zhiyuan, Ma, Yizhan, Javed, Rabia, Bao, Jie, Liang, Fang, Guo, Weihong, Tian, Xiaohong, Fan, Jun, Yu, Tianhao, Ao, Qiang“…Results: Our results demonstrate that BNC has a network of nanofibers and retains some bioactive molecules, including collagen I, collagen IV, laminin, fibronectin, glycosaminoglycans, nerve growth factor, and brain-derived neurotrophic factor. …”
Publicado 2023
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1400“…Furthermore, GAT229 attenuated nerve injuries by normalizing the brain-derived neurotrophic factor and the nerve growth factor mRNA expression levels in the DRG neurons. …”
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