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1481“…RFP expression was also shown by flow cytometry and replicating virus was cultured from exposed fetuses. Nerve growth factor and its TrkA receptor were upregulated in RSV- infected fetal lungs and co-localized with increased cholinergic innervation. …”
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1482“…Nerve growth factor (NGF), a member of the neurotrophin family, is responsible for the maintenance and survival of cholinergic neurons in the basal forebrain. …”
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1483por Basile, John R., Binmadi, Nada O., Zhou, Hua, Yang, Ying-Hua, Paoli, Antonio, Proia, Patrizia“…In this study, we demonstrate that exposure of supraphysiological doses of methandienone and 17-α-methyltestosterone are toxic to the neuron-like differentiated pheochromocytoma cell line PC12, as confirmed by toxicity on neurite networks responding to nerve growth factor and the modulation of the survival and apoptosis-related proteins ERK, caspase-3, poly (ADP-ribose) polymerase and heat-shock protein 90. …”
Publicado 2013
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1484“…Several neurotrophic signaling pathways are activated in the hippocampus of both wild type and FAD mice, including brain derived neurotrophic factor (BDNF) and nerve growth factor (NGF), and this increase is accompanied by the upregulation of the BDNF receptor, tyrosine kinase B (TrkB). …”
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1485por Reetz, Julia, Genz, Berit, Meier, Claudia, Kowtharapu, Bhavani S., Timm, Franziska, Vollmar, Brigitte, Herchenröder, Ottmar, Abshagen, Kerstin, Pützer, Brigitte M.“…Therefore, we designed a peptide of the nerve growth factor (NGF(p)) with specific affinity for the p75 neurotrophin receptor (p75NTR) present on HSCs. …”
Publicado 2013
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1486por Osikowicz, Maria, Longo, Geraldine, Allard, Simon, Cuello, A Claudio, Ribeiro-da-Silva, Alfredo“…We hypothesized that this sprouting and pain-related behavior were caused by an increase in nerve growth factor (NGF) levels. In this study, we investigated whether the inhibition of mature NGF degradation, using a matrix metalloproteinase 2 and 9 (MMP-2/9) inhibitor, was sufficient to reproduce a similar phenotype. …”
Publicado 2013
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1487por Park, Bit-Na-Ri, Kim, Seok Won, Cho, Sung-Rae, Lee, Ji Yong, Lee, Young-Hee, Kim, Sung-Hoon“…We analyzed the expression levels of regulators such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF) and histone deacetylase (HDAC) 1 in the brain following thoracic contusive SCI. …”
Publicado 2013
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1488“…Here we demonstrate that nerve growth factor (NGF) regulates the levels of IP(5) and IP(6) during PC12 differentiation. …”
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1489“…NHE5 knockdown reduces phosphorylation of Akt and Erk1/2 and impairs neurite outgrowth in response to nerve growth factor (NGF) treatment. Of interest, although both phosphoinositide 3-kinase–Akt and Erk signaling are activated by NGF-TrkA, NGF-induced Akt-phosphorylation appears to be more sensitively affected by perturbed endosomal pH. …”
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1490por Tamplenizza, Margherita, Lenardi, Cristina, Maffioli, Elisa, Nonnis, Simona, Negri, Armando, Forti, Stefania, Sogne, Elisa, De Astis, Silvia, Matteoli, Michela, Schulte, Carsten, Milani, Paolo, Tedeschi, Gabriella“…Our findings indicate that, in PC12 cells grown without Nerve Growth Factor (NGF), the roughness of nanostructured TiO(2) triggers neuritogenesis by activating the expression of nitric oxide synthase (NOS) and the phospho-extracellular signal-regulated kinase 1/2 (pERK1/2) signaling. …”
Publicado 2013
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1491por Choi, Sun-Il, Go, Jun, Kim, Ji-Eun, Lee, Young-Ju, Kwak, Moon-Hwa, Jung, Young-Jin, Hwang, Dae-Youn“…The concentration of nerve growth factor (NGF) in serum was also higher in AEtRLP7-treated Tg2576 mice than vehicle-treated Tg2576 mice. …”
Publicado 2013
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1492mTOR Signaling Cascade in Psoriatic Disease: Double Kinase mTOR Inhibitor a Novel Therapeutic Target“…In support of this hypothesis we have earlier reported that growth factors (nerve growth factor (NGF) and platelet-derived growth factor (PDGF)) and relevant cytokines (interleukin (IL)-17, IL-22) known to be critical for psoriasis, psoriatic arthritis, and rheumatoid arthritis activate the mTOR signaling system. …”
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1493por Baker, Simon C, Stahlschmidt, Jens, Oxley, Jon, Hinley, Jennifer, Eardley, Ian, Marsh, Fiona, Gillatt, David, Fulford, Simon, Southgate, Jennifer“…The nerve fascicles, which were positive for NFP, S100 and the p75 low-affinity nerve growth factor receptor (NGFR), were generally associated with a well-developed and in places, prominent, epithelial membrane antigen(+)/NGFR(+) perineurium. …”
Publicado 2013
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1494“…Neurotrophins including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) have neurogenesis, neurotrophic, or neuroprotective effects and are expressed in developing teeth. …”
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1495por JUNG, SUN-YOUNG, KIM, DAE-YOUNG, YUNE, TAE YOUNG, SHIN, DONG-HOON, BAEK, SANG-BIN, KIM, CHANG-JU“…Treadmill exercise enhanced hindlimb motor function and increased expression of nerve growth factor (NGF), NT-3 and IGF-1 in the SCI rats. …”
Publicado 2014
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1496mRNA-Mediated Gene Delivery Into Human Progenitor Cells Promotes Highly Efficient Protein Expressionpor Wiehe, Juliane M, Ponsaerts, Peter, Rojewski, Markus T, Homann, Joerg M, Greiner, Jochen, Kronawitter, Desiree, Schrezenmeier, Hubert, Hombach, Vinzenz, Wiesneth, Markus, Zimmermann, Oliver, Torzewski, Jan“…The truncated low affinity nerve growth factor receptor (ÄLNGFR) is a marker gene approved for human in vivo application. …”
Publicado 2007
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1497por Balzamino, Bijorn Omar, Biamonte, Filippo, Esposito, Graziana, Marino, Ramona, Fanelli, Francesca, Keller, Flavio, Micera, Alessandra“…Both Reelin and Nerve Growth Factor (NGF) exert crucial roles in retinal development. …”
Publicado 2014
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1498por Shin, Eun-Young, Lee, Chan-Soo, Yun, Cheong-Yong, Won, So-Yoon, Kim, Hyong-Kyu, Lee, Yong Hee, Kwak, Sahng-June, Kim, Eung-Gook“…Finally, stimulation with nerve growth factor induced transient dissociation of the NM II–GEF complex, which was closely correlated with the kinetics of Cdc42 and Rac1 activation. …”
Publicado 2014
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1499por Thauerer, Bettina, Voegele, Paul, Hermann-Kleiter, Natascha, Thuille, Nikolaus, de Araujo, Mariana E. G., Offterdinger, Martin, Baier, Gottfried, Huber, Lukas A., Baier-Bitterlich, Gabriele“…In this study, we investigated the role of LAMTOR2 in nerve growth factor (NGF)-mediated neuronal differentiation. …”
Publicado 2014
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1500“…Also, it has been shown that different subtypes of neural stem/progenitor cells (CD 34, CD 45, nestin) are involved in the innate repair of plasticity mechanisms by the injured brain, in which Nerve Growth Factor (NGF) acts as chemotactic agents to recruit such cells. …”
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