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41por Medina, Felipe S., Hunt, Gavin R., Gray, Russell D., Wild, J. Martin, Kubke, M. FabianaEnlace del recurso
Publicado 2013
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42“…It was shown that amyloid-β fragment 25-35 significantly inhibits the cell cycle progression of neural stem cells against the background of stimulation of their differentiation and reduced production of growth factors by neuroglia. The inhibitory role of ERK1/2 and p38 in relation to the proliferative activity of neural stem cells and the secretory activity of glial elements was revealed. …”
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46“…Since neuroglia respond effectively to stimuli within in vivo environments on the micron scale, adult glial physiology has remarkable synergy with microscale systems. …”
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47“…Two pioneering studies published a century ago –“Something about the physiological significance of neuroglia” (Ramón y Cajal, 1897) and “A contribution to the understanding of neuroglia in the human brain” (Ramón y Cajal, 1913)—focused on glial cells and their role in brain physiology. …”
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48“…In this review, we discuss what is currently known regarding the expression patterns of various mGluRs in neuroglia and how Aβ and tau alter the normal mGluR function in the neuroglia and contribute to the pathophysiology of AD.…”
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49“…Unembedded frozen sections and polyvinyl alcohol-embedded sections may be used to demonstrate the activities of DPNH-tetrazolium reductase localized in mitochondria and ergastoplasm, TPNH-tetrazolium reductase localized in mitochondria, ATPase (and/or apyrase or ADPase) in cell membranes, and acid phosphatase in lysosomes.(1) Among the observations recorded are: (1) the presence of lysosomes in all cells of the brain; (2) the presence of numerous large lysosomes near the nuclei of capillary endothelial cells; (3) a polarized arrangement of large lysosomes in epithelial cells of the ependyma and choroid plexus; (4) the presence of ATPase activity in the cell membranes of some neurons; (5) the presence of either an apyrase or combination of ATPase and ADPase in the cell membranes of neuroglia and capillaries; (6) the presence of both DPNH- and TPNH-tetrazolium reductase activities in neuroglia; (7) the presence of DPNH- and TPNH-tetrazolium reductase activities in mitochondria and of DPNH-tetrazolium reductase activity in Nissl substance. …”
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50por Zanette, Simone Azevedo, Dussan-Sarria, Jairo Alberto, Souza, Andressa, Deitos, Alicia, Torres, Iraci Lucena Silva, Caumo, Wolnei“…BACKGROUND: Fibromyalgia (FM) is conceptualized as a central sensitization (CS) condition, that presents high serum brain-derived neurotrophic factor (BDNF) and neuroglia activation. Although the S100B protein regulates neuroglia functions, it has been traditionally used as a proxy of central nervous system damage. …”
Publicado 2014
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51por Serwanski, David R., Rasmussen, Andrew L., Brunquell, Christopher B., Perkins, Scott S., Nishiyama, AkikoEnlace del recurso
Publicado 2018
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52“…However, these receptors are also present at neuroglia (astrocytes, oligodendrocytes) although at a considerably lower density. …”
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53por Choi, Songyeon, Kim, Kyeongmin, Kwon, Minjee, Bai, Sun Joon, Cha, Myeounghoon, Lee, Bae Hwan“…The aim of this study was to investigate pain alleviation effects after neuroglia inhibition in the IC during the early or late phase of pain development. …”
Publicado 2022
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55por Renz-Polster, Herbert, Tremblay, Marie-Eve, Bienzle, Dorothee, Fischer, Joachim E.“…Here we explore the hypothesis that a common denominator of the pathobiological processes in ME/CFS may be central nervous system dysfunction due to impaired or pathologically reactive neuroglia (astrocytes, microglia and oligodendrocytes). …”
Publicado 2022
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56“…In recent years, it has been recognized that different families of neuroglia are not merely support cells for neurons but rather key and active elements in the physiology and pathology of the nervous system. …”
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58por Hopkins, Seantel, Gottipati, Manoj K., Montana, Vedrana, Bekyarova, Elena, Haddon, Robert C., Parpura, VladimirEnlace del recurso
Publicado 2018
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59por Vanderheyden, William M., Lefton, Micah, Flores, Carlos C., Owada, Yuji, Gerstner, Jason R.Enlace del recurso
Publicado 2022
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60“…BACKGROUND: We have found that acetate supplementation significantly reduces neuroglia activation and pro-inflammatory cytokine release in a rat model of neuroinflammation induced with lipopolysaccharide. …”
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