Mostrando 101 - 120 Resultados de 4,546 Para Buscar '"nonsense"', tiempo de consulta: 0.19s Limitar resultados
  1. 101
    “…Finally, we deal with the intrinsic ambiguities of emotions by interpreting the confusions between categories (‘fuzzy world’). We use acted nonsense speech from the GEMEP corpus, emotional ‘distractors’ as categories not entailed in the test set, real-life noises that mask the clear recordings, and different sizes of the training set for machine learning. …”
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  2. 102
    “…Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved and well-characterized biological mechanism that ensures the fidelity and regulation of gene expression. …”
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  3. 103
  4. 104
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  8. 108
    “…Nonsense-mediated decay (NMD) is a conserved mRNA quality control process that eliminates transcripts bearing a premature termination codon. …”
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  9. 109
    “…RESULTS: We have isolated five sup45-n (n from nonsense) mutations that cause nonsense substitutions in the following amino acid positions of eRF1: Y53 → UAA, E266 → UAA, L283 → UAA, L317 → UGA, E385 → UAA. …”
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  10. 110
    “…We have therefore hypothesized that suppression of splicing (SOS) at latent 5′ splice sites regulates alternative 5′ splice site selection in a way that prevents the production of toxic nonsense mRNAs and verified this idea by showing that the removal of such in-frame stop codons is sufficient to activate latent splicing. …”
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  11. 111
    por Metzstein, Mark M, Krasnow, Mark A
    Publicado 2006
    “…Nonsense-mediated mRNA decay (NMD) is a cellular surveillance mechanism that degrades transcripts containing premature translation termination codons, and it also influences expression of certain wild-type transcripts. …”
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  12. 112
    Publicado 1993
    “…The identification of this nonsense mutation provides us with a solid basis on which molecular mechanisms underlying the alteration in the neuronal cytoskeletal architecture in the mutant should be interpreted.…”
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  13. 113
    por Zia, Amin, Moses, Alan M
    Publicado 2011
    “…CONCLUSIONS: This demonstrates that the evolutionary conservation context of the sequences that harbour insertions, deletions and nonsense mutations can be used to predict and rank the effects of the mutations.…”
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  14. 114
  15. 115
    “…Nonsense Mediated Decay (NMD) degrades transcripts that contain a premature STOP codon resulting from mistranscription or missplicing. …”
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  16. 116
  17. 117
    “…In this study, we tested the hypothesis that the CLCNKB W610X mutation can be rescued in vitro using aminoglycoside antibiotics, which are known to induce translational read-through of a nonsense mutation. The CLCNKB cDNA was cloned into a eukaryotic expression vector and the W610X nonsense mutation was generated by site-directed mutagenesis. …”
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  18. 118
    “…Nonsense-mediated messenger RNA (mRNA) decay (NMD) is a mRNA degradation pathway that regulates a significant portion of the transcriptome. …”
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  19. 119
  20. 120
    “…Nonsense-mediated mRNA decay (NMD) limits the production of aberrant mRNAs containing a premature termination codon and also controls the levels of endogenous transcripts. …”
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