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  1. 365361
    “…Despite individually seeking out alternative exercise options during lockdown, group average exercise capacity deteriorated even in this motivated and exercise-conscious group. …”
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    Closure of outpatient cardiac rehabilitation during the first COVID-19 lockdown in Austria in spring 2020 resulted in deteriorating physical exercise capacity: a mixed-methods study
  2. 365362
    “…As outcome we defined CPR, shock and in hospital death. RESULTS: Out of 198 patients 126 were male (63.6%) and 72 female (36.4%), with a mean age of 65±12 years. …”
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    Frequency and outcome of acute coronary syndrome during the Covid-19 pandemic
  3. 365363
    por Costa, Matthew L, Achten, Juul, Ooms, Alexander, Png, May Ee, Cook, Jonathan A, Lamb, Sarah E, Hedley, Helen, Dias, Joseph, Dritsaki, Melina, Dakin, Helen, Jones, Jonathan, Mckee, Andrew, Smith, Kevin, Hamadto, Mohamed, Gwilym, Steve, Chesser, Tim, Candal-Couto, Jaime, Hing, Caroline, Giddin, David, Johnston, Phil, Ullah, Aamer, Williams, John, Eardley, Will, Srinivasan, Makaram, Sampalli, Sridharrao, Farrar, Mark, Roberts, Chris, Mohanty, Khitish, MacLeod, Iain, Sarda, Praveen, Elseehy, Amr, Rossiter, Nigel, Warwick, David, Peach, Chris, MacKay, David, Benson, Richard, Watts, Adam, Young, Jonathan, Shah, Feisal, Lipscombe, Stephen, Ng, Aaron, Charalambous, Charalambos P, Sheriden, Barnaby, Theivendran, Kanthan, Sanjay, Pulimamidi, Nanda, Rajesh, Bateman, Antony, Butler, Michael, Keast-Butler, Oliver, McAndrew, Andrew, Chevannes, Wystan, Kankanalu, Pradeep, Wijendra, Asanka, Fontalis, Andreas, Afifi, Hytham, Killen, Marie-Clare, Higgin, Ryan, Wignadasan, Warran, Wong, Ken, Gibson, Catherine, Beale, Harry, Jennings, Bob, Kennedy, James, Williamson, Mark, Rasidovic, Damir, Jenner, Lydia, Tadros, John Baha, Milner, Steve, Duncan, James, Kerr, Sally, Nordin, Louise, Weston, Matt, Payton, Olivia, Oni, Tofi, Zhao, Craig, Gill, Sukhdeep, Iqbal, Mohammad, Killen, Marie-Clare, Aneiba, Khaled, Wignadasan, Warran, Pillai, Dilip, Hughes, Luke, Crosby, Jonathan, Whitehouse, Mike, Corbett, Thomas, Iqbal, Arshad, Buchan, Steph, Beddard, Laura, Vardhan, Venkat, Beamish, Becky, Jones, Matt, Holley, Jonathan, Morrell, Rebecca, Lerner, Robin, Draper, Kylea
    Publicado 2022
    “…MAIN OUTCOME MEASURES: The primary outcome measure was the Patient Rated Wrist Evaluation (PRWE) score at 12 months (five questions about pain and 10 about function and disability; overall score out of 100 (best score=0 and worst score=100)). …”
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    Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial
  4. 365364
    “…Whilst procedural caveats were identified by the public consultation, out of 2639 people contacted by PRINCIPLE following a positive test result, no one raised a concern about being approached. …”
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    Development and evaluation of rapid data-enabled access to routine clinical information to enhance early recruitment to the national clinical platform trial of COVID-19 community treatments
  5. 365365
    “…Three participants in the PE group and 1 participant in the CPT group were withdrawn from treatment, and 3 participants in each treatment dropped out owing to serious adverse events. CONCLUSIONS AND RELEVANCE: This randomized clinical trial found that although PE was statistically more effective than CPT, the difference was not clinically significant, and improvements in PTSD were meaningful in both treatment groups. …”
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    Comparison of Prolonged Exposure vs Cognitive Processing Therapy for Treatment of Posttraumatic Stress Disorder Among US Veterans: A Randomized Clinical Trial
  6. 365366
    “…Among which, 250 cases HPV-16 E6, 96 cases HPV-31 E6, 216 cases HPV-33 E6, 288 cases HPV-52 E6 and 405 cases HPV-58 E6 were successfully amplified, 17, 6, 6, 13, and 4 non-synonymous nucleotide mutations were respectively detected in HPV-16, 31, 33, 52, and 58 E6, 7 positive selection sites of α-9 HPV E6 were selected out (D32E of HPV-16 E6, K35N, K93N and R145I of HPV-33 E6, K93R of HPV-52 E6, K93N and R145K of HPV-58 E6). …”
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    The polymorphism analysis and epitope predicted of Alphapapillomavirus 9 E6 in Sichuan, China
  7. 365367
    “…The ER and human health risk assessment of Cu, Pb, and Zn were compared in an integrative and accurate manner after we reassessed the HM data mentioned in the literature. The synthesis carried out in this review provided the basis for us to consider Cu, Pb, and Zn as being of localized elevated levels. …”
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    Ecological-Health Risk Assessments of Heavy Metals (Cu, Pb, and Zn) in Aquatic Sediments from the ASEAN-5 Emerging Developing Countries: A Review and Synthesis
  8. 365368
    “…Questions were modelled after quality measures set out by the American Academy of Neurology, specifically eliciting information on falls, non-motor symptoms, exercise regime and medication-related symptoms. …”
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    A cross-sectional study of knowledge and practices in the management of patients with Parkinson’s disease amongst public practice-based general practitioners and geriatricians
  9. 365369
    “…To evaluate anti-cardiac fibrosis activity of recombinant LAP, an experimental study was carried out and is reported here. METHODS: The pET28a-LAP plasmid was constructed and transformed into E. coli C43 (DE3) competent cells. …”
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    Prokaryotic expression, purification and evaluation of anti-cardiac fibrosis activity of recombinant TGF-β latency associated peptide
  10. 365370
    “…Reducing m(6)A levels by knocking out METTL3 and overexpressing ALKBH5 suppressed 3D-spheroid generation in LUAD cells and intra-pulmonary tumor formation in mice. …”
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    The essential roles of m(6)A RNA modification to stimulate ENO1-dependent glycolysis and tumorigenesis in lung adenocarcinoma
  11. 365371
    “…Among our results, cg25713625 in the STEAP3 metalloreductase gene (STEAP3) stood out. Specifically, in comparing the highest cg25713625 DNAm trajectory group with the lowest, we observed significant associations (i.e., based on p-values less than an empirical significance threshold) with unfavorable GOS at 3 and 12 months (OR = 11.7, p = 0.0006 and OR = 15.6, p = 0.0018, respectively) and death at 3 and 12 months (OR = 19.1, p = 0.0093 and OR = 12.8, p = 0.0041, respectively). …”
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    Iron homeostasis pathway DNA methylation trajectories reveal a role for STEAP3 metalloreductase in patient outcomes after aneurysmal subarachnoid hemorrhage
  12. 365372
    “…Researchers wanted to find out more about this. They selected 3 medical articles about illnesses that affect different age groups: psoriasis (younger patients), multiple sclerosis (middle-aged patients), and rheumatoid arthritis (older patients). …”
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    Optimizing Readability and Format of Plain Language Summaries for Medical Research Articles: Cross-sectional Survey Study
  13. 365373
    “…The primary surgery was reported for 2129 grafts(92.7%).Out of those, foot and ankle procedure represented 97.4% of the procedures. …”
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    Donor Site Morbidity of Calcaneal, Distal and Proximal Tibial Cancellous Autografts in Foot and Ankle Surgery: A Systematic Review and Meta-Analysis of 2296 Grafts
  14. 365374
    “…Mean follow up was 2.9+/-0.2 (range from 2.7 to 3.1) months. 2 out of 3 patients simultaneously benefited of a Medial Calcaneal Displacement Osteotomy (MDCO 10mm) and a Lateral Column Lengthening (LCL 8mm). …”
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    Short-Term Outcomes of the Lapicotton Technique in the Treatment of Progressive Collapsing Foot Deformity
  15. 365375
    “…METHODS: This study was carried out as a national cross sectional survey. Clusters were selected across the whole country through probability proportional to size sampling with an urban/rural and demographic split that matched the national distribution of the population. …”
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    The unmet need for treatment of children with musculoskeletal impairment in Malawi
  16. 365376
    “…PATIENTS AND METHODS: The existing surgical setups for primary hip and knee arthroplasties in a university maximum care hospital with endoprosthesis center were simulated and analysed with a computer program and optimized setup suggestions were worked out, based on handover times, walking distance and ergonomic aspects determined in the program. …”
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    Increasing efficiency by optimizing table position for elective primary THA and TKA: a prospective monocentric pilot study
  17. 365377
    “…BACKGROUND: This study set out to investigate how incentives for mothers, health workers and boda–boda riders can improve the community-based referral process and deliveries in the rural community of Busoga region in Uganda. …”
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    Incentives for mothers, health workers and “boda–boda” riders to improve community-based referral process and deliveries in the rural community: a case of Busoga Region in Uganda
  18. 365378
    Publicado 2022
    “…Prespecified subgroup analyses were carried out for efficacy and safety outcomes by duration of symptoms, the presence of anti-spike neutralising antibodies, and other baseline factors. …”
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    Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial
  19. 365379
    “…We determined the level of CVD knowledge, risk perception and intention towards a healthy lifestyle in Antwerp and Nottingham using a percentage score out of 100. To identify independent socioeconomic determinants in CVD knowledge, risk perception, intention to PA and healthy diet, we performed multilevel multivariable modeling using the Antwerp dataset. …”
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    Level of cardiovascular disease knowledge, risk perception and intention towards healthy lifestyle and socioeconomic disparities among adults in vulnerable communities of Belgium and England
  20. 365380
    “…CONCLUSION: The PCI appears to be a low-cost intervention that generates a cost-effective benefit to patients from a NHS perspective if rolled out as part of routine care. Qualitative evidence has shown that the use of the PCI is supported by consultants in routine practice. …”
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    An Economic Evaluation Supported by Qualitative Data About the Patient Concerns Inventory (PCI) versus Standard Treatment Pathway in the Management of Patients with Head and Neck Cancer
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