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365941por Salas-Huetos, Albert, Ribas-Maynou, Jordi, Mateo-Otero, Yentel, Tamargo, Carolina, Llavanera, Marc, Yeste, Marc“…In terms of the presence or absence of miRNAs, and after applying the Livak method, 8 out of 10 miRNAs (bta-miR-10b, -138, -146b, -19b, -26a, -449a, -495, -7) were consistently detected in bovine sperm, whereas the other two (bta-miR-10a, and -34a) were absent. …”
Publicado 2023
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365942por Mangioni, Davide, Panigada, Mauro, Palomba, Emanuele, Bobbio, Chiara, Chatenoud, Liliane, Alagna, Laura, Fumagalli, Jacopo, Gori, Andrea, Grancini, Anna, Guzzardella, Amedeo, Lombardi, Andrea, Matinato, Caterina, Meli, Andrea, Muscatello, Antonio, Porretti, Laura, Tomasello, Mara, Trombetta, Elena, Valenti, Luca, Bandera, Alessandra, Grasselli, Giacomo“…Immune biomarkers to rule-in/rule-out VAP diagnosis, although promising, have not yet been validated. …”
Publicado 2023
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365943“…Yet, this is not happening in routine clinical practice both in primary and secondary care and patients fall out of safety netting resulting in AFF. We need robust pathway and safety netting for patients who are on long term treatment. …”
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365944por Gjorgjievski, Dragan, Stavrikj, Katarina, Jordan, Rachel, Adab, Peymane, Stanoevski, Gjorgji, Stamenova, Aleksandra, Krstevska, Emilija, Simonovska, Sara, Trpcheski, Fillip, Adams, Rachel, Easter, Christina, Rai, Kiran, Cheng, Kar Keung, Chi, Chunhua, Cooper, Brendan G., Correia-de-Sousa, Jaime, Dickens, Andrew P., Enocson, Alexandra, Gale, Nicola, Jolly, Kate, Jowett, Sue, Maglakelidze, Mariam, Maghlakelidze, Tamaz, Martins, Sonia, Sitch, Alice, Stelmach, Rafael, Turner, Alice, Williams, Siân, Farley, Amanda“…However, a small effect cannot be ruled out as the proportion quitting was low and therefore estimates were imprecise. …”
Publicado 2023
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365945por Bickendorf, Kate, Qi, Fang, Peirce, Kelli, Natalwala, Jay, Chapple, Vincent, Liu, Yanhe“…A search of MEDLINE, EMBASE, and the Cochrane Library for relevant studies was carried out on 10 October 2022, using key words relevant to ‘blastocyst collapse’ and ‘time-lapse imaging’. …”
Publicado 2023
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365946por Protopopoff, Natacha, Mosha, Jacklin F., Messenger, Louisa A., Lukole, Eliud, Charlwood, Jacques D., Wright, Alexandra, Kessy, Enock, Manjurano, Alphaxard, Mosha, Franklin W., Kleinschmidt, Immo, Rowland, Mark“…METHODS: A four-group cluster randomized trial (CRT) using a two-by-two factorial design was carried out between January 2014 and December 2017. A total of 48 clusters, were randomized in a 1:1:1:1 ratio to the following treatment groups, each intervention being provided once in 2015: 1/std-LLIN; 2/PBO-pyrethroid LLIN; 3/std-LLIN + Indoor Residual Spraying (IRS) and 4/PBO-Pyrethroid-LLIN + IRS. …”
Publicado 2023
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365947por Chiloiro, Sabrina, Giampietro, Antonella, Gessi, Marco, Lauretti, Liverana, Paolo, Mattogno Pier, Carlino, Angela, Olivi, Alessandro, RIndi, Guido, Pontecorvi, Alfredo, De Marinis, Laura, Doglietto, Francesco, Bianchi, Antonio“…Pts not-naïve to acromegaly therapies before surgery, with history of radiotherapy of head and neck within 10 years before pituitary surgery, with immune-related disease were ruled out. Results: Eighteen pts (41.9%) were fg-SRLs resistant: 14 were females (77.8%), with a median age of 36.5 (IQR:13) and with cavernous sinus invasion in 12 cases (66.7%). …”
Publicado 2023
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365948por Tessnow, Alex, Wyne, Kathleen L, Patrick Schneiderman, Chris, Pinsky, Brett, Guo, Dianlin, Barger, Bruce, Antunez Flores, Oscar“…Study Limitations: Claims data may incompletely capture the conditions and outcomes documented in the medical records and prevalence may be overestimated due to miss or rule out coding. The active surveillance of thyroid function conducted in NHANES might also have contributed to the differences. …”
Publicado 2023
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365949por Vidana Gamage, Hashni Epa, Shahoei, Sayyed Hamed, Albright, Samuel, Nguyen, Tiffany, Farmer, Rachel Elizabeth, Weisser, Erin, Bautista Rivas, Rafael Ovidio, Schane, Claire P, Wang, Yu, Nelczyk, Adam, Ma, Liqian, Tiwari, Srishti, Gupta, Anasuya Das, Bendre, Shruti, Apetoh, Lionel, Hergenrother, Paul, Nelson, Erik Russell“…In order to investigate the role of NR0B2 in vivo, we monitored the growth of tumors grafted into mice that had NR0B2 genetically knocked out in the myeloid lineage (NR0B2(fl/fl);LysMCre(+)) and respective control mice (NR0B2(wt/wt);LysMCre(+)). …”
Publicado 2023
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365950por Suryadevara, Varun, Rashmi, K G, Prasad, Aravind, Sunthoju, Venkatesh, Priyamvada, P S, Govindarajalou, Ramkumar, Sahoo, Jayaprakash, Kamalanathan, Sadishkumar, Naik, Dukhabandhu“…A detailed history was taken, and a physical examination was done to rule out secondary causes of osteoporosis. Serum creatinine, electrolytes, 25 hydroxy vitamin [25 (OH)D], and intact parathyroid hormone (iPTH) were analysed. …”
Publicado 2023
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365951por Papadimitriou, Dimitrios T, Dermitzaki, Eleni, Christopoulos, Panagiotis, Papagianni, Maria, Kleanthous, Kleanthis, Marakaki, Chrysanthi, Papadimitriou, Anastasios, Mastorakos, George“…From 4 pre-T1D, 1 negativized T1Ab (follow-up 1 yr), 1 with +HLA did not progress to T1D (follow-up 3.3 yrs) and 2 with +T1Ab developed T1D in 6m/3yrs. Three out of 8 children with T1D at presentation progressed immediately to overt disease, 5 showed complete remission for 1 yr (1m-2yrs). …”
Publicado 2023
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365952“…After conducting post-hoc analysis, it was found out that obese (≥30) group has highest mean of TSH (4.88±11.23) level, Age (28.97±4.04), B.P. count (120/77 (±11/±8)) and prevalence of acanthosis nigricans (34.2%). …”
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365953por Bénard, Élodie, Drolet, Mélanie, Laprise, Jean-François, Gingras, Guillaume, Jit, Mark, Boily, Marie-Claude, Bloem, Paul, Brisson, Marc“…The doses saved by introducing one-dose routine vaccination could offer the opportunity to vaccinate girls before they age out of the vaccination window of 9–14 years and, potentially, to vaccinate boys or older age groups. …”
Publicado 2023
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365954por Zhu, Lanlan, Li, Ping, Zhang, Guangyi, He, Zhiyong, Tao, Xingyu, Ji, Yicheng, Yang, Wenjing, Zhu, Xiaofang, Luo, Wanying, Liao, Wenjian, Chen, Chuanhui, Liu, Yang, Zhang, Wei“…Intriguingly, every mgrB-mutated CoR-hvKP isolate possessed at least two virulence genes akin to the pLVPK-like virulence plasmid, with iroB and rmpA2 standing out. Their virulence was empirically validated both in vitro and in vivo. …”
Publicado 2023
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365955Publicado 2023“…Three pairs of small interfering RNAs targeting YKL-40 (si-YKL-40-1/2/3) and the negative control (NC) were designed and used to transfect A549 cells, respectively, and the expression of YKL-40 was determined by RT-qPCR and Western blot. si-YKL-40-3 was screened out for subsequent experiments. In A549 cells, si-YKL-40-3 and si-NC were transfected and, then, IL-1β (20 ng/mL) was added in for culturing. …”
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365956por Muthoka, Esther Nthenya, Usmael, Kedir, Embaye, Saba Mehari, Abebe, Abigiya, Mesfin, Tigist, Kazembe, Dorothy, Ahmedin, Mediha, Namuganza, Stella, Kahabuka, Monica, Atim, Mary Gorret, Manyazewal, Tsegahun“…Data was extracted from eligible studies and an aggregated data meta-analysis was carried out with data pooled as risk ratio (RR) with a 95% confidence interval (CI), using RevMan software (5.4). …”
Publicado 2023
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365957por Heald, Adrian H., Jenkins, David A., Williams, Richard, Mudaliar, Rajshekhar N., Khan, Amber, Syed, Akheel, Sattar, Naveed, Khunti, Kamlesh, Naseem, Asma, Bowden-Davies, Kelly A., Gibson, J. Martin, Ollier, William“…There is less data on outcomes for people with type 1 diabetes (T1D) following SARS-CoV-2 infection than for those with type 2 diabetes (T2D). In this study we set out to determine the relative likelihood of hospital admission following SARS-CoV-2 infection in people with T1D when compared to those without T1D. …”
Publicado 2023
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365958por Krauze, Andra V., Zhao, Yingdong, Li, Ming-Chung, Shih, Joanna, Jiang, Will, Tasci, Erdal, Cooley Zgela, Theresa, Sproull, Mary, Mackey, Megan, Shankavaram, Uma, Tofilon, Philip, Camphausen, Kevin“…Adjustment for age, sex, and other clinical covariates and hierarchical clustering of significant differentially expressed proteins was carried out, and Gene Set Enrichment analyses were performed using the Hallmark gene sets. …”
Publicado 2023
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365959por Linders, D. G. J., Deken, M. M., van Dam, M. A., Wasser, M. N. J. M., Voormolen, E. M. C., Kroep, J. R., van Dongen, G. A. M. S., Vugts, D., Oosterkamp, H. M., Straver, M. E., van de Velde, C. J. H., Cohen, D., Dibbets-Schneider, P., van Velden, F. H. P., Pereira Arias-Bouda, L. M., Vahrmeijer, A. L., Liefers, G. J., de Geus-Oei, L. F., Hilling, D. E.“…In six patients, a HER2-targeted PET/CT scan was acquired before and after NAT. Two out of six patients had residual tumor at microscopic analysis. …”
Publicado 2023
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365960por Stasi, Alessandra, Fiorentino, Marco, Franzin, Rossana, Staffieri, Francesco, Carparelli, Sabrina, Losapio, Rosa, Crovace, Alberto, Lacitignola, Luca, Cimmarusti, Maria Teresa, Murgolo, Francesco, Stufano, Monica, Cafiero, Cesira, Castellano, Giuseppe, Sallustio, Fabio, Ferrari, Chiara, Ribezzi, Mario, Brienza, Nicola, Schirinzi, Annalisa, Di Serio, Francesca, Grasso, Salvatore, Pontrelli, Paola, Tupin, Cyrille, Barbaras, Ronald, Keyserling-Peyrottes, Constance, Crovace, Antonio, Gesualdo, Loreto“…We investigated the effects of CER-001, an engineered HDL-mimetic, in a swine model of LPS-induced acute kidney injury (AKI) and a Phase 2a clinical trial, aiming to better understand its molecular basis in systemic inflammation and renal function. METHODS: We carried out a translational approach to study the effects of HDL administration on sepsis. …”
Publicado 2023
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