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  1. 366021
    “…Such future metabolic signatures will: (1) provide predictive, prognostic, diagnostic, and surrogate markers of diverse disease states; (2) inform on underlying molecular mechanisms of diseases; (3) allow for sub-classification of diseases, and stratification of patients based on metabolic pathways impacted; (4) reveal biomarkers for drug response phenotypes, providing an effective means to predict variation in a subject’s response to treatment (pharmacometabolomics); (5) define a metabotype for each specific genotype, offering a functional read-out for genetic variants: (6) provide a means to monitor response and recurrence of diseases, such as cancers: (7) describe the molecular landscape in human performance applications and extreme environments. …”
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    Metabolomics enables precision medicine: “A White Paper, Community Perspective”
  2. 366022
    por Deakin, Claire T., Yasin, Shireena A., Simou, Stefania, Arnold, Katie A., Tansley, Sarah L., Betteridge, Zoe E., McHugh, Neil J., Varsani, Hemlata, Holton, Janice L., Jacques, Thomas S., Pilkington, Clarissa A., Nistala, Kiran, Wedderburn, Lucy R., Armon, Kate, Ellis‐Gage, Joe, Roper, Holly, Briggs, Vanja, Watts, Joanna, McCann, Liza, Roberts, Ian, Baildam, Eileen, Hanna, Louise, Lloyd, Olivia, Wadeson, Susan, Riley, Phil, McGovern, Ann, Ryder, Clive, Scott, Janis, Thomas, Beverley, Southwood, Taunton, Al‐Abadi, Eslam, Wyatt, Sue, Jackson, Gillian, Amin, Tania, Wood, Mark, VanRooyen, Vanessa, Burton, Deborah, Davidson, Joyce, Gardner‐Medwin, Janet, Martin, Neil, Ferguson, Sue, Waxman, Liz, Browne, Michael, Friswell, Mark, Swift, Alison, Jandial, Sharmila, Stevenson, Vicky, Wade, Debbie, Sen, Ethan, Smith, Eve, Qiao, Lisa, Watson, Stuart, Duong, Claire, Venning, Helen, Satyapal, Rangaraj, Stretton, Elizabeth, Jordan, Mary, Mosley, Ellen, Frost, Anna, Crate, Lindsay, Warrier, Kishore, Stafford, Stefanie, Hasson, Nathan, Maillard, Sue, Halkon, Elizabeth, Brown, Virginia, Juggins, Audrey, Smith, Sally, Lunt, Sian, Enayat, Elli, Kassoumeri, Laura, Beard, Laura, Glackin, Yvonne, Almeida, Beverley, Marques, Raquel, Dowle, Stefanie, Papadopoulou, Charis, Murray, Kevin, Ioannou, John, Suffield, Linda, Al‐Obaidi, Muthana, Lee, Helen, Leach, Sam, Smith, Helen, McMahon, Anne‐Marie, Chisem, Heather, Kingshott, Ruth, Wilkinson, Nick, Inness, Emma, Kendall, Eunice, Mayers, David, Etherton, Ruth, Bailey, Kathryn, Clinch, Jacqui, Fineman, Natalie, Pluess‐Hall, Helen, Vallance, Lindsay, Akeroyd, Louise, Leahy, Alice, Collier, Amy, Cutts, Rebecca, De Graaf, Hans, Davidson, Brian, Hartfree, Sarah, Pratt, Danny
    Publicado 2016
    “…This study was carried out to investigate whether histopathologic findings and myositis‐specific autoantibodies (MSAs) have prognostic significance in juvenile DM. …”
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    Muscle Biopsy Findings in Combination With Myositis‐Specific Autoantibodies Aid Prediction of Outcomes in Juvenile Dermatomyositis
  3. 366023
    “…Stigmella caryaefoliella (Clemens, 1861) and Zimmermannia bosquella (Chambers, 1878) are taken out of synonymy and re-instated as full species. …”
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    Revised classification and catalogue of global Nepticulidae and Opostegidae (Lepidoptera, Nepticuloidea)
  4. 366024
    “…Two targeted next-generation sequencing (NGS) gene panels, one composed of 56 genes and the other of 12 genes, were used for ultra-deep sequencing. To rule out potential NGS-based errors, orthogonal mutation validation was performed using digital PCR and Sanger sequencing. …”
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    Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study
  5. 366025
    “…EUC plus HAP showed better results than did EUC alone for the secondary outcomes of disability (adjusted mean difference −2·73 [–4·39 to −1·06]; p=0·001), days out of work (−2·29 [–3·84 to −0·73]; p=0·004), intimate partner physical violence in women (0·53 [0·29–0·96]; p=0·04), behavioural activation (2·17 [1·34–3·00]; p<0·0001), and suicidal thoughts or attempts (0·61 [0·45–0·83]; p=0·001). …”
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    The Healthy Activity Program (HAP), a lay counsellor-delivered brief psychological treatment for severe depression, in primary care in India: a randomised controlled trial
  6. 366026
    “…The fatty acid was extracted by hot and cold extraction method and the analyses were carried out by GC. The amino acid profile was done by the amino acid analyzer. …”
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    Chemical composition and pharmacological significance of Anethum Sowa L. Root
  7. 366027
    “…AIM: The study was undertaken to find out the physicochemical characteristics, selected processing-related parameters and activity of selected enzymes in Surti goat milk. …”
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    Comparison of Surti goat milk with cow and buffalo milk for physicochemical characteristics, selected processing-related parameters and activity of selected enzymes
  8. 366028
    “…Then, germination was carried out and pre-treated raw and pre-treated germinated sorghum grains were analyzed for total oil yield, fatty acid composition and unsaturated fatty acids (Un-SFA)/saturated fatty acids (SFA) ratio by gas chromatography. …”
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    Lipids characterization of ultrasound and microwave processed germinated sorghum
  9. 366029
    “…The objective of this work was to design and build a low cost portable laser device for stimulation of acupuncture points, considered here as small localized biosources (SLB), without stimulating any sensory nerves via shock or heat and to find out a suitable method for objectively evaluating its stimulating effect. …”
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    Design and testing of low intensity laser biostimulator
  10. 366030
    “…In order to evaluate the relative importance of TBI in the context of all injuries, proportions of TBI YLLs out of overall injury YLLs were calculated. The total number of TBI YLLs was estimated by extrapolating the pooled crude rate of TBI YLLs in the 16 analyzed countries to the total population of the 28 member states of the EU (EU-28). …”
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    Years of life lost due to traumatic brain injury in Europe: A cross-sectional analysis of 16 countries
  11. 366031
    “…Longitudinal analyses for HNO, HNOR and α angle were carried out using repeated measures ANOVA. An a priori power analysis utilizing data from a previous short-term study showed that 17 hips were required in order to obtain a power > 85% to find a change in HNOR of 0.02. …”
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    Long-term Osseous Remodeling after Femoral Head-neck Junction Osteochondroplasty
  12. 366032
    “…PLAIN ENGLISH SUMMARY: It is recommended that research studies are carried out with or by patients and the public through their involvement from the beginning and in as many stages as possible (known as PPI). …”
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    Combining PPI with qualitative research to engage ‘harder-to-reach’ populations: service user groups as co-applicants on a platform study for a trial
  13. 366033
    “…While literature on power and participation informs the debate, there are relatively few published case studies of how this can play out through the lived experience of PPI in research; early findings highlight key issues around access to knowledge, resources, and interpersonal respect. …”
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    Learning to work together – lessons from a reflective analysis of a research project on public involvement
  14. 366034
    por Jehangir, Asad, Parkman, Henry P
    Publicado 2017
    “…METHODS: Patients referred to our tertiary care academic center from May 2016 to July 2017, with established diagnosis or symptoms suggestive of Gp filled out the Patient Assessment of Upper GI Symptoms, abdominal pain and demographics questionnaires, and underwent gastric emptying and blood tests. …”
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    Chronic opioids in gastroparesis: Relationship with gastrointestinal symptoms, healthcare utilization and employment
  15. 366035
    por Rana, Suresh, Zheng, Yuanshui
    Publicado 2015
    “…The imaging, treatment planning, and beam delivery were carried out following the guidelines provided by the IROC. …”
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    Impact of grid size on uniform scanning and IMPT plans in XiO treatment planning system for brain cancer
  16. 366036
    “…All participants were included in the intention-to-treat analysis and per-protocol analysis, except for those who dropped out in the per-protocol analysis. The composite primary outcome was clearance of asexual parasites and fever by day 7, and absence of recrudescent infection by parasites with the same molecular markers from days 8 to 42 (defined as cure). …”
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    AQ-13, an investigational antimalarial, versus artemether plus lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria: a randomised, phase 2, non-inferiority clinical trial
  17. 366037
    “…Visual analog scale score compared at the time for administration of rescue analgesic between the groups come out to be statistically significant. CONCLUSION: Addition of 0.75 μg/kg dexmedetomidine to 0.5% levobupivacaine for supraclavicular plexus block shortens sensory and motor block onset time and extends sensory block, motor block, and analgesia duration.…”
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    Effect of Locally Administered Dexmedetomidine as Adjuvant to Levobupivacaine in Supraclavicular Brachial Plexus Block: Double-blind Controlled Study
  18. 366038
    “…This report summarizes the results of observational analyses carried out to assess the impact of these IRS campaigns on malaria incidence rates reported through local and district health systems before and after spraying. …”
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    An observational analysis of the impact of indoor residual spraying with non-pyrethroid insecticides on the incidence of malaria in Ségou Region, Mali: 2012–2015
  19. 366039
    “…Statistical analyses were carried out using Stata 13 software. We used the estimated population during the 3-year period based on the 2010 Brazilian Census to calculate person-years at risk. …”
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    T131. INCIDENCE OF FIRST-EPISODE PSYCHOSIS IN THE CATCHMENT AREA OF RIBEIRÃO PRETO, BRAZIL
  20. 366040
    “…MAIN RESULTS AND THE ROLE OF CHANCE: It was found that 609 out of 1401 identified proteins were common to the three follicle developmental stages investigated. …”
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    Protein profile of mouse ovarian follicles grown in vitro
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