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366041por Dagnachew, Shimelis, Tsegaye, Biniam, Awukew, Addissu, Tilahun, Meseret, Ashenafi, Hagos, Rowan, Tim, Abebe, Getachew, Barry, Dave J., Terefe, Getachew, Goddeeris, Bruno M.“…In the present work; questionnaire survey, cross-sectional and experimental studies were carried out to; a) assess the utilization of trypanocidal drugs; b) determine the prevalence of bovine trypanosomosis and; c) assess the drug resistant problems respectively in Tsetse and non-tsetse infested areas on NW Ethiopia. …”
Publicado 2017
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366042por Blackburn, Steven, McLachlan, Sarah, Jowett, Sue, Kinghorn, Philip, Gill, Paramjit, Higginbottom, Adele, Rhodes, Carol, Stevenson, Fiona, Jinks, Clare“…Less impact was reported on developing funding applications, managing or carrying out the research. The main cost of PPI for researchers was their time. …”
Publicado 2018
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366043por Mody, Aaloke, Sikazwe, Izukanji, Czaicki, Nancy L., Wa Mwanza, Mwanza, Savory, Theodora, Sikombe, Kombatende, Beres, Laura K., Somwe, Paul, Roy, Monika, Pry, Jake M., Padian, Nancy, Bolton-Moore, Carolyn, Holmes, Charles B., Geng, Elvin H.“…BACKGROUND: Although randomized trials have established the clinical efficacy of treating all persons living with HIV (PLWHs), expanding treatment eligibility in the real world may have additional behavioral effects (e.g., changes in retention) or lead to unintended consequences (e.g., crowding out sicker patients owing to increased patient volume). …”
Publicado 2018
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366044por Johnson, Samuel, Henschke, Nicholas, Maayan, Nicola, Mills, Inga, Buckley, Brian S, Kakourou, Artemisia, Marshall, Rachel“…We summarized dichotomous outcomes using risk ratios (RRs) and continuous outcomes using mean differences (MDs), and used meta‐analyses where appropriate. We carried out a subsidiary appraisal and analysis of studies with critical risk of bias for the primary outcome, as these are often cited to support using ribavirin. …”
Publicado 2018
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366045por Jenkins, David J. A., Kendall, Cyril W. C., Lamarche, Benoît, Banach, Monica S., Srichaikul, Korbua, Vidgen, Edward, Mitchell, Sandy, Parker, Tina, Nishi, Stephanie, Bashyam, Balachandran, de Souza, Russell J., Ireland, Christopher, Pichika, Sathish C., Beyene, Joseph, Sievenpiper, John L., Josse, Robert G.“…The primary outcome was change in HbA(1c). The study was carried out in a hospital clinical research centre and concluded in 2008. …”
Publicado 2018
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366046por Littman, Lisa“…Parents reported subjective declines in their AYAs’ mental health (47.2%) and in parent-child relationships (57.3%) since the AYA “came out” and that AYAs expressed a range of behaviors that included: expressing distrust of non-transgender people (22.7%); stopping spending time with non-transgender friends (25.0%); trying to isolate themselves from their families (49.4%), and only trusting information about gender dysphoria from transgender sources (46.6%). …”
Publicado 2018
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366047por Cortese, Samuele, Adamo, Nicoletta, Del Giovane, Cinzia, Mohr-Jensen, Christina, Hayes, Adrian J, Carucci, Sara, Atkinson, Lauren Z, Tessari, Luca, Banaschewski, Tobias, Coghill, David, Hollis, Chris, Simonoff, Emily, Zuddas, Alessandro, Barbui, Corrado, Purgato, Marianna, Steinhausen, Hans-Christoph, Shokraneh, Farhad, Xia, Jun, Cipriani, Andrea“…Primary outcomes were efficacy (change in severity of ADHD core symptoms based on teachers' and clinicians' ratings) and tolerability (proportion of patients who dropped out of studies because of side-effects) at timepoints closest to 12 weeks, 26 weeks, and 52 weeks. …”
Publicado 2018
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366048por Vincent, Kathleen L., Moss, John A., Marzinke, Mark A., Hendrix, Craig W., Anton, Peter A., Pyles, Richard B., Guthrie, Kate M., Dawson, Lauren, Olive, Trevelyn J., Butkyavichene, Irina, Churchman, Scott A., Cortez, John M., Fanter, Rob, Gunawardana, Manjula, Miller, Christine S., Yang, Flora, Rosen, Rochelle K., Vargas, Sara E., Baum, Marc M.“…The crossover, open-label portion of the trial (N = 6) consisted of 7 d of continuous TDF pod-IVR use, a wash-out phase, and 7 d of continuous TDF-FTC pod-IVR use. …”
Publicado 2018
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366049por Lin, Haotian, Long, Erping, Ding, Xiaohu, Diao, Hongxing, Chen, Zicong, Liu, Runzhong, Huang, Jialing, Cai, Jingheng, Xu, Shuangjuan, Zhang, Xiayin, Wang, Dongni, Chen, Kexin, Yu, Tongyong, Wu, Dongxuan, Zhao, Xutu, Liu, Zhenzhen, Wu, Xiaohang, Jiang, Yuzhen, Yang, Xiao, Cui, Dongmei, Liu, Wenyan, Zheng, Yingfeng, Luo, Lixia, Wang, Haibo, Chan, Chi-Chao, Morgan, Ian G., He, Mingguang, Liu, Yizhi“…Ten-fold cross-validation and out-of-bag (OOB) methods were applied for internal validation. …”
Publicado 2018
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366050por Okujava, Rusudan, Garcia-Alcalde, Fernando, Haldimann, Andreas, Zampaloni, Claudia, Morrissey, Ian, Magnet, Sophie, Kothari, Nimmi, Harding, Ian, Bradley, Kenneth“…Additionally, MEM/NAC1:1 displayed MIC ≤8 mg/L for 33 out of 37 CAZ/AVI-resistant MDR EB isolates. MEM/NAC had a similar activity to MEM alone against Pseudomonas spp. and Acinetobacter spp. …”
Publicado 2018
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366051por Lassalle, Marion, Colas, Sandrine, Rudnichi, Annie, Zureik, Mahmoud, Dray-Spira, Rosemary“…Some caveats should be mentioned: severity of DCM or HF was not available and residual confounding cannot be ruled out despite considering many covariates. Our findings suggest that cardiac function should be regularly monitored in patients with metallic head THAs. …”
Publicado 2018
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366052por Shenfield, F., de Mouzon, J., Scaravelli, G., Kupka, M., Ferraretti, A.P., Prados, F.J., Goossens, V.“…MAIN RESULTS AND THE ROLE OF CHANCE: Out of 34 EIM members, we received answers regarding OoC regulations and funding conditions from 27, whilst 17 countries had recorded data for OoC, and 12 for OtC. …”
Publicado 2017
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366053por Favi, Evaldo, Puliatti, Carmelo, Sivaprakasam, Rajesh, Ferraresso, Mariano, Ambrogi, Federico, Delbue, Serena, Gervasi, Federico, Salzillo, Ilaria, Raison, Nicholas, Cacciola, Roberto“…Patients with BK viral load ≥ 1000 copies/mL were diagnosed BK-viremia and underwent histological assessment to rule out nephropathy. In case of BK-viremia, immunosuppression was minimized according to a prespecified protocol. …”
Publicado 2019
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366054por D’Almeida, Olga, Mothar, Omar, Bondzie, Esther Apraku, Lieumo, Yolande, Tagne, Laure, Gupta, Sumeet, Volkert, Thomas, Levine, Stuart, Tagne, Jean-Bosco“…RESULTS: Due to their effectiveness as intracellular vesicles transporting miR-200c into, out, and between parts of the cells, miR-200c is encapsulated with cholesterol, an integral part of the biological membranes with very important physical properties of the vehicle. …”
Publicado 2019
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366055por Walters, Raymond K., Polimanti, Renato, Johnson, Emma C., McClintick, Jeanette N., Adams, Mark J., Adkins, Amy E., Aliev, Fazil, Bacanu, Silviu-Alin, Batzler, Anthony, Bertelsen, Sarah, Biernacka, Joanna M., Bigdeli, Tim B., Chen, Li-Shiun, Clarke, Toni-Kim, Chou, Yi-Ling, Degenhardt, Franziska, Docherty, Anna R., Edwards, Alexis C., Fontanillas, Pierre, Foo, Jerome C., Fox, Louis, Frank, Josef, Giegling, Ina, Gordon, Scott, Hack, Laura M., Hartmann, Annette M., Hartz, Sarah M., Heilmann-Heimbach, Stefanie, Herms, Stefan, Hodgkinson, Colin, Hoffmann, Per, Hottenga, Jouke Jan, Kennedy, Martin A., Alanne-Kinnunen, Mervi, Konte, Bettina, Lahti, Jari, Lahti-Pulkkinen, Marius, Lai, Dongbing, Ligthart, Lannie, Loukola, Anu, Maher, Brion S., Mbarek, Hamdi, McIntosh, Andrew M., McQueen, Matthew B., Meyers, Jacquelyn L., Milaneschi, Yuri, Palviainen, Teemu, Pearson, John F., Peterson, Roseann E., Ripatti, Samuli, Ryu, Euijung, Saccone, Nancy L., Salvatore, Jessica E., Sanchez-Roige, Sandra, Schwandt, Melanie, Sherva, Richard, Streit, Fabian, Strohmaier, Jana, Thomas, Nathaniel, Wang, Jen-Chyong, Webb, Bradley T., Wedow, Robbee, Wetherill, Leah, Wills, Amanda G., Boardman, Jason D., Chen, Danfeng, Choi, Doo-Sup, Copeland, William E., Culverhouse, Robert C., Dahmen, Norbert, Degenhardt, Louisa, Domingue, Benjamin W., Elson, Sarah L., Frye, Mark A., Gäbel, Wolfgang, Hayward, Caroline, Ising, Marcus, Keyes, Margaret, Kiefer, Falk, Kramer, John, Kuperman, Samuel, Lucae, Susanne, Lynskey, Michael T., Maier, Wolfgang, Mann, Karl, Männistö, Satu, Müller-Myhsok, Bertram, Murray, Alison D., Nurnberger, John I., Palotie, Aarno, Preuss, Ulrich, Räikkönen, Katri, Reynolds, Maureen D., Ridinger, Monika, Scherbaum, Norbert, Schuckit, Marc A., Soyka, Michael, Treutlein, Jens, Witt, Stephanie, Wodarz, Norbert, Zill, Peter, Adkins, Daniel E., Boden, Joseph M., Boomsma, Dorret I., Bierut, Laura J., Brown, Sandra A., Bucholz, Kathleen K., Cichon, Sven, Costello, E. Jane, de Wit, Harriet, Diazgranados, Nancy, Dick, Danielle M., Eriksson, Johan G., Farrer, Lindsay A., Foroud, Tatiana M., Gillespie, Nathan A., Goate, Alison M., Goldman, David, Grucza, Richard A., Hancock, Dana B., Harris, Kathleen Mullan, Heath, Andrew C., Hesselbrock, Victor, Hewitt, John K., Hopfer, Christian J., Horwood, John, Iacono, William, Johnson, Eric O., Kaprio, Jaakko A., Karpyak, Victor M., Kendler, Kenneth S., Kranzler, Henry R., Krauter, Kenneth, Lichtenstein, Paul, Lind, Penelope A., McGue, Matt, MacKillop, James, Madden, Pamela A. F., Maes, Hermine H., Magnusson, Patrik, Martin, Nicholas G., Medland, Sarah E., Montgomery, Grant W., Nelson, Elliot C., Nöthen, Markus M., Palmer, Abraham A., Pedersen, Nancy L., Penninx, Brenda W.J.H., Porjesz, Bernice, Rice, John P., Rietschel, Marcella, Riley, Brien P., Rose, Richard, Rujescu, Dan, Shen, Pei-Hong, Silberg, Judy, Stallings, Michael C., Tarter, Ralph E., Vanyukov, Michael M., Vrieze, Scott, Wall, Tamara L., Whitfield, John B., Zhao, Hongyu, Neale, Benjamin M., Gelernter, Joel, Edenberg, Howard J., Agrawal, Arpana“…To discover loci associated with AD and characterize the relationship between AD and other psychiatric and behavioral outcomes, we carried out the largest GWAS to date of DSM-IV diagnosed AD. …”
Publicado 2018
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366056“…Of note, this trial deviated from the protocol after three out of eight patients who had received doxycycline and rifampicin combination therapy experienced treatment failure. …”
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366057por Littlewood, Elizabeth, Ali, Shehzad, Badenhorst, Jay, Bailey, Della, Bambra, Clare, Chew-Graham, Carolyn, Coleman, Elizabeth, Crosland, Suzanne, Gascoyne, Samantha, Gilbody, Simon, Hewitt, Catherine, Jones, Claire, Keding, Ada, Kitchen, Charlotte, McMillan, Dean, Pearson, Caroline, Rhodes, Shelley, Sloan, Claire, Todd, Adam, Watson, Michelle, Whittlesea, Cate, Ekers, David“…Sample size: 20–30 participants Outcomes: Study implementation (recruitment and attrition rates), quality of data collection at baseline and 4 months and ESI adherence (number of contacts, DNA and drop out) as per objectives 1a/b Qualitative evaluation: Semi-structured interviews with up to 10 participants and ESI facilitators and focus group(s) (range of pharmacy staff n = 8–10) will be conducted to explore the acceptability of the intervention and feasibility of the study, training and study procedures. …”
Publicado 2019
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366058por Mothe, Beatriz, Manzardo, Christian, Sanchez-Bernabeu, Alvaro, Coll, Pep, Morón-López, Sara, Puertas, Maria C., Rosas-Umbert, Miriam, Cobarsi, Patricia, Escrig, Roser, Perez-Alvarez, Núria, Ruiz, Irene, Rovira, Cristina, Meulbroek, Michael, Crook, Alison, Borthwick, Nicola, Wee, Edmund G., Yang, Hongbing, Miró, Jose M., Dorrell, Lucy, Clotet, Bonaventura, Martinez-Picado, Javier, Brander, Christian, Hanke, Tomáš“…Added Value of this Study: The present study demonstrated the concept that epitopes subdominant in natural infection, when taken out of the context of the whole HIV-1 proteome and presented to the immune system by a potent simian adenovirus prime-poxvirus MVA boost regimen, can induce strong responses in patients on antiretroviral treatment and efficiently refocus HIV-1-specific T-cells to the protective epitopes delivered by the vaccine. …”
Publicado 2019
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366059por Nagbe, Thomas, Yealue, Kwuakuan, Yeabah, Trokon, Rude, Julius Monday, Fallah, Musoka, Skrip, Laura, Agbo, Chukwuemeka, Mouhamoud, Nuha, Okeibunor, Joseph Chukwudi, Tuopileyi, Roland, Talisuna, Ambrose, Yahaya, Ali Ahmed, Rajatonirina, Soatiana, Frimpong, Joseph Asamoah, Stephen, Mary, Hamblion, Esther, Nyenswah, Tolbert, Dahn, Bernice, Gasasira, Alex, Fall, Ibrahima Socé“…It was also established that 40% of health facilities have experienced a stock out of laboratory specimens packaging supplies in the past year. …”
Publicado 2019
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366060“…The difficulty of filtering out critical short half-life infusion alarms from nonurgent alarms is a key challenge for risk management for clinicians. …”
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