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367381por Ma, Na, Sun, Mengni, Shi, Hanxing, Xue, Liangliang, Zhang, Min, Yang, Wenge, Dang, Yali, Qiao, Zhaohui“…The NTri-Multi-Apt was designed to carry many streptavidin-HRPs for colorimetric read-outs and a large load of Sybr green I in the dsDNA scaffold for the output of a fluorescent signal. …”
Publicado 2023
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367382“…We were particularly interested in learning whether any physicochemical characteristics of xenobiotics might account for outlying data points (i.e., poor prediction of human half-life from rat half-life). …”
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367383por Bylesjö, Max, Rantalainen, Mattias, Nicholson, Jeremy K, Holmes, Elaine, Trygg, Johan“…Incorporated is also a set of diagnostic tools and plot functions to simplify the visualisation of data, e.g. for detecting trends or for identification of outlying samples. The utility of the software package is demonstrated by means of a metabolic profiling data set from a biological study of hybrid aspen. …”
Publicado 2008
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367384“…A mixed prediction method that simulated random effects from both higher levels was best at identifying the outlying level two (farm-year) units of interest. It is concluded that this mixed prediction method, simulating random effects from both higher levels, is straightforward and may be of value in model criticism of multilevel logistic regression, a technique commonly used for animal health data with a hierarchical structure.…”
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367385“…Indeed, the 3D visual nature of the tool allows users to spot features in a data set, such as outlying markers and potential structural rearrangements that could cause problems with the estimation procedure and to account for them in their analysis. …”
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367386por Liu, Qiongming, Chen, Qing, Wang, Jian, Zhang, Ying, Zhou, Ying, Lin, Cong, He, Wei, He, Fuchu, Xu, Danke“…Compared to traditional resin-based coIP, MSIP results in higher sensitivity and enhanced throughput, with the additional benefit of digital read-outs. In addition, MSIP was shown to be a highly useful validation platform to confirm PPI candidates that have been identified from yeast two hybrid systems. …”
Publicado 2010
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367387“…In many organisms central nodes in the interaction network (hubs) play a crucial role for information and energy transport. Knock-outs of such hubs often lead to lethal phenotypes making them interesting drug targets. …”
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367388“…These measurements are corrupted with typical outlying patterns to numerically evaluate the algorithm performance with respect to the standard parity space algorithm. …”
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367389“…The fact that, in contrast to other RAS components, (P)RR knock-outs, even tissue-specific, are lethal, points to an important, (pro)renin-independent, function of the (P)RR. …”
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367390por Ower, Geoffrey D, Judge, Kevin A, Steiger, Sandra, Caron, Kyle J, Smith, Rebecca A, Hunt, John, Sakaluk, Scott K“…Longer trains and pulses likely promote greater mate attraction, but selection for longer intertrain durations suggests that energetic constraints may necessitate “time outs”. Playback trials confirmed the selection for longer train and pulse durations, and revealed significant stabilizing selection on dominant frequency, suggesting that the female auditory system is tightly tuned to the species-specific call frequency. …”
Publicado 2013
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367391por Cook, David A., Sorensen, Kristi J., Hersh, William, Berger, Richard A., Wilkinson, John M.“…METHODS: We conducted 11 focus groups at an academic medical center and outlying community sites. We included a purposive sample of 50 primary care and subspecialist internal medicine and family medicine physicians. …”
Publicado 2013
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367392por Gelius-Dietrich, Gabriel, Desouki, Abdelmoneim Amer, Fritzemeier, Claus Jonathan, Lercher, Martin J“…Publicly available implementations tend to be slow, impeding large scale analyses such as the genome-wide computation of pairwise gene knock-outs, or the automated search for model improvements. …”
Publicado 2013
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367393por Patel, Tulpesh, Blyth, Jacqueline C., Griffiths, Gareth, Kelly, Deirdre, Talcott, Joel B.“…However, the magnitude of these effects was significantly modulated by the stringency of data screening and the extent to which outlying values contributed to statistical analyses. …”
Publicado 2014
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367394por van Luijk, Judith, Bakker, Brenda, Rovers, Maroeska M., Ritskes-Hoitinga, Merel, de Vries, Rob B. M., Leenaars, Marlies“…Of the evaluated primary studies, 24.6% was randomized, 14.6% reported blinding of the investigator/caretaker, 23.9% blinded the outcome assessment, and 23.1% reported drop-outs. CONCLUSIONS: To improve the translation of animal data to clinical practice, systematic reviews of animal studies are worthwhile, but the internal validity of primary animal studies needs to be improved. …”
Publicado 2014
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367395por Halai, Reena, Croker, Daniel E., Suen, Jacky Y., Fairlie, David P., Cooper, Matthew A.“…However, label-free read outs gave consistently lower potency values in both native and transfected cells. …”
Publicado 2012
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367396
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367397por Tetko, Igor V., Sushko, Yurii, Novotarskyi, Sergii, Patiny, Luc, Kondratov, Ivan, Petrenko, Alexander E., Charochkina, Larisa, Asiri, Abdullah M.“…We found that compounds with reactive and unstable groups were overrepresented among outlying compounds. These compounds could decompose during storage or measurement, thus introducing experimental errors. …”
Publicado 2014
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367398por Mitou, Géraldine, Frentzel, Julie, Desquesnes, Aurore, Le Gonidec, Sophie, AlSaati, Talal, Beau, Isabelle, Lamant, Laurence, Meggetto, Fabienne, Espinos, Estelle, Codogno, Patrice, Brousset, Pierre, Giuriato, Sylvie“…Classical autophagy read-outs such as autophagosome visualization/quantification by electron microscopy and LC3-B marker turn-over assays were used to demonstrate autophagy induction and flux activation upon ALK inactivation. …”
Publicado 2015
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367399“…Therapists described their interaction with families of their clients in their earlier years of practice as a challenging and often overwhelming experience generating intense anger and frustration which sometimes led to acting outs and tempted them to give up their efforts to build an alliance with family members. …”
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367400“…Criteria based on reading speed and errors made in each sentence pair were used to exclude sentence pairs with more outlying characteristics, and to select the final group of sentence pairs. …”
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