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  1. 367461
    “…A total of 38 patients were randomized to receive combination therapy, while 30 continued on monotherapy (with placebo) (six drop outs in the combination group and three for each single drug group). …”
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    Topiramate plus nortriptyline in the preventive treatment of migraine: a controlled study for nonresponders
  2. 367462
    “…RESULTS: Liquid chromatography mass spectrometry (LC-MS), gas chromatography mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) spectroscopy were used to define the metabolome of all the possible knock-outs for the Δ9 desaturases, including for the first time intact lipids. …”
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    A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans
  3. 367463
    “…We also show that Nup214/CAN and Nup98 play no role in HIV-1 nuclear import per se: Nup214/CAN plays an indirect role in infectivity read-outs through its effect on mRNA export, while the reduction of expression of Nup98 shows a slight reduction in proviral integration. …”
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    Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration
  4. 367464
    “…The model was shown to perform well both for growth simulations in different media and gene essentiality analysis for single and double knock-outs. Further, the model was used as a scaffold for integrating transcriptomics, and flux data from four different conditions in order to identify transcriptionally controlled reactions, i.e. reactions that change both in flux and transcription between the compared conditions. …”
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    Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling
  5. 367465
    por Huygen, Kris
    Publicado 2014
    “…Using synthetic overlapping peptides, bio-informatic prediction programs and tetramer-binding studies, a number of immunodominant CD4(+) and CD8(+) T-cell epitopes have been identified in experimental animal models as well as in humans, using proliferation and Th1 cytokine secretion as main read-outs. The results from these studies are summarized in this review.…”
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    The Immunodominant T-Cell Epitopes of the Mycolyl-Transferases of the Antigen 85 Complex of M. tuberculosis
  6. 367466
    “…The current practice of floating tenders multiple times a year contributes to long lead times and stock-outs, and it hampers the manufacturer's or supplier's ability to plan and respond to the government's needs. …”
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    Strategic contracting practices to improve procurement of health commodities
  7. 367467
    “…Several guidelines have been developed for implementing standardized inpatient sign-outs, but no specific guidelines exist for outpatient handover. …”
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    A survey of primary care resident attitudes toward continuity clinic patient handover
  8. 367468
    “…Our findings highlight the need to define sufficient physiological read-outs for a given plasticity protocol and to develop predictive markers for targeted stimulation.…”
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    Efficacy and Interindividual Variability in Motor-Cortex Plasticity following Anodal tDCS and Paired-Associative Stimulation
  9. 367469
    “…Using pluripotency and cell growth as read-outs, we determined the optimal concentration of both basic fibroblast growth factor (bFGF) and neuregulin−1 beta 1 (NRG1β1). …”
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    Systematic optimization of human pluripotent stem cells media using Design of Experiments
  10. 367470
    “…The management practices of partial and total house clean-outs markedly altered soil profiles the house underlayment, thus reducing the risk of infiltration into the ground water near the farm. …”
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    Canonical Discrimination of the Effect of a New Broiler Production Facility on Soil Chemical Profiles as Related to Current Management Practices
  11. 367471
    “…A principal component analysis (PCA) model was constructed which, in combination with hierarchical cluster analysis (HCA), divided the samples into five groups. The outlying groups had different sets of dominant compounds in the extracts, which could be characterised by their elemental composition. …”
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    Chemical and Antimicrobial Profiling of Propolis from Different Regions within Libya
  12. 367472
    “…RESULTS: The process of creating quality indexes from standard DHS data was proven to be feasible, and initial results from Indonesia indicate particular disparities in the quality of care received by the poor as well as those living in outlying regions. CONCLUSIONS: The QI represents an important step forward in efforts to understand, measure and improve quality of MNCH care in developing countries.…”
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    Measuring Quality of Maternal and Newborn Care in Developing Countries Using Demographic and Health Surveys
  13. 367473
    “…Possible downstream consequences of these impacts are, e.g., local magnetopause reconnection, impulsive penetration of magnetosheath plasma into the magnetosphere, inner magnetospheric and boundary surface waves, drop outs and other variations in radiation belt electron populations, ionospheric flow enhancements, and magnetic field variations observed on the ground. …”
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    Geoeffective jets impacting the magnetopause are very common
  14. 367474
    por Smoliński, Adam, Howaniec, Natalia
    Publicado 2016
    “…Since the data set contained outliers, the construction of robust Partial Least Squares models for contaminated data set and the correct identification of outlying objects based on the robust scales were required. …”
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    Quantitative Modelling of Trace Elements in Hard Coal
  15. 367475
    “…Rationally designed perturbations (e.g., gene knock-outs) can be used to iteratively refine hypothetical models, suggesting an approach for high-throughput biological system analysis. …”
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    Linear fuzzy gene network models obtained from microarray data by exhaustive search
  16. 367476
    “…We show that although bats are present even in very densely populated urban centers, there is a large reduction in species richness compared to that of outlying areas, and that most habitat factors explaining their community composition and activity patterns are similar to those documented in less urbanized environments.…”
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    Patterns of Bat Distribution and Foraging Activity in a Highly Urbanized Temperate Environment
  17. 367477
    “…The purpose of this study was to revisit previously published results that suggested some sandflies to be arboreal and to rest on outlying plants by using Centers for Disease Control light traps to capture sandflies in vegetation, including banana plants and palmyra palm trees, in two previously sampled VL‐endemic Bihari villages. …”
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    Phlebotomine sandfly ecology on the Indian subcontinent: does village vegetation play a role in sandfly distribution in Bihar, India?
  18. 367478
    por Pedersen, Thomas Lin
    Publicado 2017
    “…The intersection and union sizes along the hierarchy are visualized using a composite dendrogram and icicle plot, which, in pangenome context, shows the evolution of pangenome and core size along the evolutionary hierarchy. Outlying elements, i.e. elements whose presence pattern do not correspond with the hierarchy, can be visualized using hierarchical edge bundles. …”
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    Hierarchical sets: analyzing pangenome structure through scalable set visualizations
  19. 367479
    “…Additional webtools and link-outs to assist in the downstream validation of candidate motifs are also provided. …”
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    FlyExpress 7: An Integrated Discovery Platform To Study Coexpressed Genes Using in Situ Hybridization Images in Drosophila
  20. 367480
    “…We applied resource selection functions to model habitat selection at three scales and analyzed for niche partitioning using the outlying mean index. Habitat selection of the two predators was mediated by spatial heterogeneity. …”
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    Spatial heterogeneity and scale‐dependent habitat selection for two sympatric raptors in mixed‐grass prairie
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