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367521por Volckmar, Julia, Gereke, Marcus, Ebensen, Thomas, Riese, Peggy, Philipsen, Lars, Lienenklaus, Stefan, Wohlleber, Dirk, Klopfleisch, Robert, Stegemann-Koniszewski, Sabine, Müller, Andreas J., Gruber, Achim D., Knolle, Percy, Guzman, Carlos A., Bruder, Dunja“…To determine whether this approach would as well be suitable to induce local antiviral effector T cells in the liver we compared different vaccine formulations based on either the targeting of DEC-205 or TLR2/6 on cross-presenting DCs or formulations not involving in vivo DC targeting. As read-outs we used in vivo hepatotropic adenovirus challenge, histology and automated multidimensional fluorescence microscopy (MELC). …”
Publicado 2017
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367522por Avidan, Ofir, Petrenko, Margarita, Becker, René, Beck, Sebastian, Linscheid, Michael, Pietrokovski, Shmuel, Jurkevitch, Edouard“…Only flp1, flp2 and flp4 were expressed; their respective gene knock-outs resulted in a complete loss of the predatory ability without losing the ability to adhere to prey cells. …”
Publicado 2017
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367523por Pahwa, Punam, Rana, Masud, Pickett, William, Karunanayake, Chandima P., Amin, Khalid, Rennie, Donna, Lawson, Josh, Kirychuk, Shelley, Janzen, Bonnie, Koehncke, Niels, Dosman, James“…Hence, the objectives are to: (i) describe the updated methodology of longitudinal SRHS—an extension of baseline survey methodology published earlier; (ii) compare baseline characteristics and the prevalences of respiratory health outcomes between drops-outs and completers; and (iii) summarize key findings based on baseline survey data. …”
Publicado 2017
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367524“…Behavioral performance was not significantly affected by prior sound exposure, with the exception of one bat after exposure to one sound. Even in this outlying case, performance recovered rapidly, by 10 min post-exposure. …”
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367525por Zimmermann, Tina, Maroso, Mattia, Beer, Annika, Baddenhausen, Sarah, Ludewig, Susann, Fan, Wenqiang, Vennin, Constance, Loch, Sebastian, Berninger, Benedikt, Hofmann, Clementine, Korte, Martin, Soltesz, Ivan, Lutz, Beat, Leschik, Julia“…Deteriorated neurogenesis in NSC-specific CB1 knock-outs additionally resulted in reduced long-term potentiation in the hippocampal formation. …”
Publicado 2018
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367526por Balliu, Brunilda, Durrant, Matthew, Goede, Olivia de, Abell, Nathan, Li, Xin, Liu, Boxiang, Gloudemans, Michael J., Cook, Naomi L., Smith, Kevin S., Knowles, David A., Pala, Mauro, Cucca, Francesco, Schlessinger, David, Jaiswal, Siddhartha, Sabatti, Chiara, Lind, Lars, Ingelsson, Erik, Montgomery, Stephen B.“…We identify 1291 and 294 genes differentially expressed and alternatively spliced with age, as well as 529 genes with outlying individual trajectories. Further, we observe a strong correlation of genetic effects on expression and splicing between the two ages, with a small subset of tested genes showing a reduction in genetic associations with expression and splicing in older age. …”
Publicado 2019
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367527por Woloszyk, Anna, Wolint, Petra, Becker, Anton S., Boss, Andreas, Fath, Weston, Tian, Yinghua, Hoerstrup, Simon P., Buschmann, Johanna, Emmert, Maximilian Y.“…Being compliant with the 3R-principles (replacement, reduction and refinement), the well-established and easy-to-handle CAM model offers many advantages such as low costs, immune-incompetence and short experimental times with high-grade read-outs when compared to conventional animal models. …”
Publicado 2019
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367528por Kautsar, Satria A, Blin, Kai, Shaw, Simon, Navarro-Muñoz, Jorge C, Terlouw, Barbara R, van der Hooft, Justin J J, van Santen, Jeffrey A, Tracanna, Vittorio, Suarez Duran, Hernando G, Pascal Andreu, Victòria, Selem-Mojica, Nelly, Alanjary, Mohammad, Robinson, Serina L, Lund, George, Epstein, Samuel C, Sisto, Ashley C, Charkoudian, Louise K, Collemare, Jérôme, Linington, Roger G, Weber, Tilmann, Medema, Marnix H“…Finally, we improved the user experience by adding new features such as query searches and a statistics page, and enabled direct link-outs to chemical structure databases. The repository is accessible online at https://mibig.secondarymetabolites.org/.…”
Publicado 2020
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367529por Holtgrewe, Manuel, Stolpe, Oliver, Nieminen, Mikko, Mundlos, Stefan, Knaus, Alexej, Kornak, Uwe, Seelow, Dominik, Segebrecht, Lara, Spielmann, Malte, Fischer-Zirnsak, Björn, Boschann, Felix, Scholl, Ute, Ehmke, Nadja, Beule, Dieter“…Variants passing the filter are listed with their annotations and many useful link-outs to genome browsers, other gene/variant data portals, and external tools for variant assessment. …”
Publicado 2020
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367530por Ushie, Boniface Ayanbekongshie, Juma, Kenneth, Kimemia, Grace, Magee, Maggie, Maistrellis, Emily, McGovern, Terry, Casey, Sara E.“…At public and private health facilities, participants reported staffing shortages and increased stock-outs of family planning and safe abortion commodities. …”
Publicado 2020
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367531por Alex, Varsha, Motevasseli, Tahmineh, Freeman, William R., Jayamon, Jefy A., Bartsch, Dirk-Uwe G., Borooah, Shyamanga“…In normal eyes, all retinal layer volumes calculated by the two softwares were moderate-strongly correlated except OUTLY. In iAMD eyes, GCIPL, INL, ONL, INLY, TRV layer volumes were moderate-strongly correlated between softwares. …”
Publicado 2021
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367532por Bernard, Marie-Clotilde, Boudet, Florence, Pineda-Peña, Andrea-Clemencia, Guinet-Morlot, Françoise“…The RIG interference on PVRV-NG, observed transiently at Day 7, was similar to that on PVRV and tended to be lower than that on HDCV using both read-outs. In summary, the results generated in the hamster model showed that RIG induced similar or less interference on PVRV-NG than the standard-of-care vaccines.…”
Publicado 2022
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367533“…Random-effects meta-analysis and heterogeneity tests will be undertaken, and tests for publication bias, outlying highly-influential observations. If insufficient data is founded or studies are highly heterogeneous, a narrative synthesis will be conducted. …”
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367534por Kabwama, Steven Ndugwa, Wanyenze, Rhoda K., Kiwanuka, Suzanne N., Namale, Alice, Ndejjo, Rawlance, Monje, Fred, Wang, William, Lazenby, Siobhan, Kizito, Susan, Troeger, Christopher, Liu, Anne, Lindgren, Helena, Razaz, Neda, Ssenkusu, John, Sambisa, William, Bartlein, Rebecca, Alfvén, Tobias“…However, multi-month drug dispensing led to drug stock-outs while community drug distribution was associated with stigma. …”
Publicado 2022
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367535por Morris, John T., Enochs, Ian C., Besemer, Nicole, Viehman, T. Shay, Groves, Sarah H., Blondeau, Jeremiah, Ames, Cory, Towle, Erica K., Grove, Laura Jay W., Manzello, Derek P.“…Detailed comparison of reef types reveals that mid-channel reefs in the Florida Keys have the highest net carbonate production (0.84 kg CaCO(3) m(−2) year(−1)) and indicates that these reefs may be hold-outs for reef development throughout the region. …”
Publicado 2022
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367536por Eric S. Reyes, Marc, Camille M. Alday, Angeli, Jay J. Aurellano, Alexa, Raven R. Escala, Sahara, Ermelo V. Hernandez, Piolo, Esrom P. Matienzo, John, Marian R. Panaguiton, Khim, Charmaine C. Tan, Angeli, Zsila, Ágnes“…Lesbians also reported higher satisfaction with outness. Regarding IPV, gay men expressed slightly more favorable attitudes toward abuse, which could make them at risk of becoming victims or perpetrators. …”
Publicado 2022
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367537por Tefelska, Angelika Magdalena“…Previously published measurements of charged kaons were used to determine the K$^{∗}$(892)$^{0}$ to K^± multiplicity ratios, which allow to estimate time interval between chemical and kinetic freeze-outs. The obtained mass and width of K$^{∗}$(892)$^{0}$ mesons peak were presented and compared with the available world experimental data. …”
Publicado 2020
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367538por Zhang, Dengfeng“…The FE of the ITk-Strip detector, the ABCStar chip, is an ASIC with 256 channels that read outs the hit information collected on each silicon strip. …”
Publicado 2023
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367539por Dadari, Ibrahim, Ropiti, Laura, Patson, Aven, Okia, Philip, Narasia, Jenny, Hare’e, Timothy, Namohunu, Salome, Ogaoga, Divinal, Gaiofa, Jenny, Usuf, Effua“…Calculating vaccine wastage rates supports vaccine forecasting and prevents stock outs/over-stock at central and immunisation delivery facilities. …”
Publicado 2022
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367540“…One community particularly vulnerable to the impacts of surveillance is the queer community, where an outing, at least in the United States, imposes a potential loss of housing and employment and may subject the outed person to violence. Libraries–particularly public and school libraries–have once again become sites of conflict and resistance, with queer people and materials increasingly coming under attack both physically and legally. …”
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